E-mail:  birui@mail.kiz.ac.cn
Education and Professinal Appointment:
2018.01 - Current: Associate professor; Kunming Institute of Zoology, Chinese Academy of Sciences
2015.01 - 2017.12: Assistant professor; Kunming Institute of Zoology, Chinese Academy of Sciences
2009.09 - 2014.12: Ph.D., Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming, Yunnan Province, China
2005.09 - 2009.06: Bachelor, School of Life Science, Yunnan University, Kunming, Yunnan Province, China

First author (#) and Corresponding author (*):

1.  Guo H, Guo L, Yuan Y, Liang XY, Bi R*. 2022. 
    Co-occurrence of m.15992A>G and m.15077G>A Is Associated With a High Penetrance of Maternally Inherited Hypertension in a Chinese Pedigree.
    Am J Hypertens, 35(1):96-102.

2. Zheng Q#, Bi R#, Xu M, Zhang D-F, Tan L-W, Lu Y-P, Yao Y-G*. 2021.
    Exploring the genetic association of the ABAT gene with Alzheimer's disease.
     Mol Neurobiol, 58(5):1894-1903

3. Bi R*, Zhang W, Zhang D-F, Xu M, Fan Y, Hu Q-X, Jiang H-Y, Tan L, Li T, Fang Y, Zhang C, Yao Y-G*. 2018.
    Genetic association of the cytochrome c oxidase-related genes with Alzheimer's disease in Han Chinese. 
    Neuropsychopharmacology, 43: 2264 - 2276.

4. Wang D#, Fan Y#, Malhi M#, Bi R#, Wu Y, Xu M, Yu X-F, Long H, Li Y-Y, Zhang D-F*, Yao Y-G*. 2018. 
   Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese. 
   Am J Hum Genet, 102: 794 – 805.

5. Bi R#, Kong L-L#, Xu M, Li G-D, Zhang D-F, Alzheimer’s Disease Neuroimaging Initiative, Li T, Fang Y, Zhang C, Zhang B, Yao Y-G*, 
   The Arc gene confers genetic susceptibility to Alzheimer’s disease in Han Chinese. 
    Mol Neurobiol, 55: 1217-1226.

6. Li H#, Bi R#, Fan Y, Wu Y, Tang Y, Li Z, He Y, Zhou J, Tang J*, Chen X*, Yao Y-G*. 2017.
   mtDNA heteroplasmy in monozygotic twins discordant for schizophrenia.
   Mol Neurobiol, 54: 4343-4352.

7. Xiang Q, Bi R*, Xu M, Zhang D-F, Tan L, Zhang C, Fang Y, Yao Y-G*. 2017.
   Rare genetic variants of the transthyretin gene are associated with Alzheimer’s disease in Han Chinese.
   Mol Neurobiol, 54: 5192-5200.

8. Bi R, Tang J, Zhang W, Li X, Chen SY, Yu D, Chen X, Yao YG*. 2016.
   Mitochondrial genome variations and functional characterization in Han Chinese families with schizophrenia.
   Schizophr Res, 171(1-3):200-206.

9. Wang HZ#, Bi R#, Hu QX, Xiang Q, Zhang C, Zhang DF, Zhang W, Ma X, Guo W, Deng W, Zhao L, Ni P, Li M, Fang Y, Li T, Yao YG*. 2016. 
   Validating GWAS-identified risk loci for Alzheimer's disease in Han Chinese populations. 
   Mol Neurobiol, 53(1):379-390.

10. Wang HZ#, Bi R#, Zhang DF, Li GD, Ma XH, Fang Y, Li T, Zhang C, Yao YG*.
    Neprilysin confers genetic susceptibility to Alzheimer's disease in Han Chinese.
    Mol Neurobiol, 53: 4883-92.

11. Guo L, Yuan Y, Bi R*. 2016.
     Mitochondrial DNA mutation m.5512A > G in the acceptor-stem of mitochondrial tRNATrp causing maternally inherited essential hypertension.
     Biochem Biophys Res Commun, 479: 800-807.

12. Bi R, Logan I, Yao Y-G*. 2016.
     Leber hereditary optic neuropathy: a mitochondrial disease unique in many ways. In: H. Singh, S.-S. Sheu. (eds). 
     Pharmacology of Mitochondria. Handbook of Experimental Pharmacology, 240:309-336

13. Bi R, Zhang W, Yu D, Li X, Wang HZ, Hu QX, Zhang C, Lu W, Ni J, Fang Y, Li T, Yao YG*. 2015.
    Mitochondrial DNA haplogroup B5 confers genetic susceptibility to Alzheimer's disease in Han Chinese.
   Neurobiol Aging, 36:1604 e7-16.

14. Bi R, Zhao L, Zhang C, Lu W, Feng JQ, Wang Y, Ni J, Zhang J, Li GD, Hu QX, Wang D, Yao YG*, Li T*. 2014.
     No association of the LRRK2 genetic variants with Alzheimer's disease in Han Chinese individuals.
     Neurobiol Aging, 2014, 35:444 e5-9.

15. Bi R, Zhang AM, Jia X, Zhang Q, Yao YG*. 2012.
    Complete mitochondrial DNA genome sequence variation of Chinese families with mutation m.3635G>A and Leber hereditary optic neuropathy.
    Mol Vis, 18:3087-3094.

16. Bi R, Zhang AM, Yao YG*. 2011.
    Leber's hereditary optic neuropathy.
    Ophthalmology, 118: 1489 - 1489 e1481.

17. Bi R#, Li WL#, Chen MQ, Zhu Z, Yao YG*. 2011.
     Rapid identification of mtDNA somatic mutations in gastric cancer tissues based on the mtDNA phylogeny. 
     Mutat Res, 709-710:15-20.

18. Bi R, Zhang AM, Zhang W, Kong QP, Wu BL, Yang XH, Wang D, Zou Y, Zhang YP, Yao YG*. 2010. 
     The acquisition of an inheritable 50-bp deletion in the human mtDNA control region does not affect the mtDNA copy number in peripheral blood cells. 
     Hum Mutat, 31(5):538-543.

19. Bi R, Zhang AM, Yu D, Chen D, Yao YG*. 2010.
     Screening the three LHON primary mutations in the general Chinese population by using an optimized multiplex allele-specific PCR. 
     Clin Chim Acta, 411(21-22):1671-1674.

Patent Application:

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