| Basic information |
| Official Symbol | ZNF135 |
| Description | zinc finger protein 135 |
| Other Aliases | ZNF61, ZNF78L1, pHZ-17, pT3 |
| Other Description | zinc finger protein 135 (clone pHZ-17); zinc finger protein 61; zinc finger protein 78-like 1 (pT3) |
| Mutation type | premature termination 100:K->TAA |
| Location | Scaffold144336_1:637335 631244 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| ZNF135 |
CAGGAGCAAGTGACCTTTGAGGACGTGGTTGTGGACTTCACTCAGGAGGA GTGGAGGCAGCTGGAACCTGCCCAGAGGACTCTGTTCCGTGATGTGATGC TGGAGACCCTCAGGCTCCTGATCTCTGTGGGATATTGGTTTCCGAAGCCA GAAGTCATCTCCCTACTGGAACAGGAGGTAGAGCCATGGGCACTGGACTC CAGAATTCCCCAAGGTGTGTGCAACAGGAATTAATGGACATTTCCATTTT CTGTTCTTTCAGACTTGGAAACTCCACTTTCAGTTTCAAAGCTAGGCATC TCTGAAGAAACATGCAACACTGTCATTGAGGTAAGAAGACTCCTGTGGGG TGGCCTGTGGTACTCTAGGGGTGAGGACACTGAGGGCCACTGGGAATGGA GTCTCAAAAGTTCAGTGAACTGTGTGGTGCAAGCAGCCTTCACATCTGTG AAGACTCCCACCCAGAAGGAATGTCAGGGAAACAGGTTTGGGGAAAACCT GAATATGAGCTCTAATCTCCCAGTTCAACCAATGACTCCTGAAAGACAGG GTCCTCCCATGTGGGGAACACGTGGAAAGAGGGAGAAACTGGACTCAAAG TTAAATGCTCCACAGAAAACCTATGCAAGAGAGAAATCTTACAGATGTCA GGAATGTGGAAAGGACTTTAATCATAGCTCAGCACTCATTGAACACCACC GAACGCACACAGGAGAGAGACCTTATAAATGTCAGGAATGTGGAAAAGGC TTCCGAAACAGCTCTGCACTTACCAAACACCAGAGAATCCACACTGGGGA AAAACCCTATAAATGCACTCAATGTGGGAGGACCTTCAACCAAATTGCTC CACTGATCCAGCACCAGAGAACTCACACAGGTGAGAAGCCCTATGAGTGC AGTGAGTGTGGGAAATCCTTCAGTTTTAGGTCTTCTTTCAGCCAGCATGA GAGGACTCACACGGGTGAGAAGCCCTATGAGTGCAGTGAATGTGGGAAGG CCTTCCGGCAGAGTATTCACCTCACACAACACCTACGAATCCACACTGGA GAGAAACCTTATCAGTGTGGAGAGTGTGGCAAGGCTTTCAGCCACAGCTC ATCCTTGACCAAACACCAGCGAATTCACACTGGAGAAAAGCCCTATGAGT GCCATGAGTGTGGGAAAGCCTTCACCCAGATCACGCCACTGATTCAGCAT CAGAGGACCCACACAGGAGAGAAGCCTTATGAGTGCAGTGAGTGTGGGAA GGCCTTTAGCCAGAGCACACTCCTGACTGAGCACCGGAGGATTCACACGG GTGAGAAGCCATATGGATGCAATGAGTGTGGCAAAACCTTCAGTCACAGC TCTTCACTAAGCCAGCATGAGCGGACACACACAGGAGAAAAGCCCTATGA GTGTAGTCAGTGTGGGAAGGCCTTCCGGCAGAGCACACACCTCACTCAGC ACCAGAGAATCCACACAGGGGAAAAACCCTATGAATGTAATGACTGTGGC AAGGCCTTCAGCCATAGCTCATCCCTAACAAAACATCAGCGGATCCACAC TGGGGAGAAACCCTATGAATGTAATGAATGTGGCAGAGCCTTCAGCCAGC TTGCTCCCCTTATTCAGCATCAGAGGATCCACACAGGAGAGAAGCCCTAT GAGTGTAATGAGTGTAGCAGAGCCTTCAGCCAGAGCTCCCTTCTCATAGA ACACCAGAGGATTCACACCAAGGAAAAGCCCTATGGGTGCAATGAATGCG GGAAATCTTTTAGTCACAGCTCATCACTCAGCCAGCATGAAAGGACACAC ACTGGGGAAAAGCCCTATGAATGTCAGGATTGTGGAAAATCCTTCAGGCA GAGCACCCACCTCACTCAGCACCGGAGAATCCACACAGGAGAGAAGCCGT ATGAGTGTGGGAACTGTGGGAAGGCCTTTACACACAGCTCCTCCCTTACC AAGCACCAGAGAACTCATACTGGA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 682 | 23 | 682 | Premature termination 100:K->TAA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
ArgGluGlnValThrPheGluAspValValValGlyPheSerGlnGluGluTrpGlyGln
|||||||||||||||||||||||||||||| ||| |||||||||||| |||
GlnGluGlnValThrPheGluAspValValValAspPheThrGlnGluGluTrpArgGln
CAGGAGCAAGTGACCTTTGAGGACGTGGTTGTGGACTTCACTCAGGAGGAGTGGAGGCAG
LeuLysProAlaGlnArgThrLeuTyrArgAspValMetLeuAspThrPheArgLeuLeu
||| |||||||||||||||||| ||||||||||||||| ||| |||||||||
LeuGluProAlaGlnArgThrLeuPheArgAspValMetLeuGluThrLeuArgLeuLeu
CTGGAACCTGCCCAGAGGACTCTGTTCCGTGATGTGATGCTGGAGACCCTCAGGCTCCTG
ValSerVal{G} >>>> Target Intron 1 >>>> {ly}HisTrpLeuProLys
||||||{|} 1498 bp {||} ||| ||||||
IleSerVal{G}++ ++{ly}TyrTrpPheProLys
ATCTCTGTG{G}gt ag{GA}TATTGGTTTCCGAAG
ProAsnValIleSerLeuLeuGluGlnGluAlaGluLeuTrpAlaValGluSerArgLeu
||| |||||||||||||||||||||||| ||| |||||| ||||||
ProGluValIleSerLeuLeuGluGlnGluValGluProTrpAlaLeuAspSerArgIle
CCAGAAGTCATCTCCCTACTGGAACAGGAGGTAGAGCCATGGGCACTGGACTCCAGAATT
ProGlnGlyValTyr >>>> Target Intron 2 >>>> ProGluIleLysGlyH
|||||||||||| 2620 bp
ProGlnGlyValCys-+ +-AsnArgAsn***TrpT
CCCCAAGGTGTGTGCct aaAACAGGAATTAATGGA
isPheGlnPheLeuLeuLeuSerAspLeuGluThrArgProLysValLysLeuSerValL
||| ||| |||||||||||||||||| |||||||||
hrPheProPheSerValLeuSerAspLeuGluThr------------ProLeuSerValS
CATTTCCATTTTCTGTTCTTTCAGACTTGGAAACT------------CCACTTTCAGTTT
euLysGlnGlyIleSerGluGluIleSerAsnSerValIleLeuValGluArgPheLeuT
||| ||||||||||||||| ||| |||||| ||| ||| ||||
erLysLeuGlyIleSerGluGluThrCysAsnThrValIleGluValArgArgLeuLeuT
CAAAGCTAGGCATCTCTGAAGAAACATGCAACACTGTCATTGAGGTAAGAAGACTCCTGT
rpAspGlyLeuTrpTyrCysArgGlyGluAspThrGluGlyHisTrpGluTrpSerCysG
|| |||||||||||| ||||||||||||||||||||||||||||||||||||
rpGlyGlyLeuTrpTyrSerArgGlyGluAspThrGluGlyHisTrpGluTrpSerLeuL
GGGGTGGCCTGTGGTACTCTAGGGGTGAGGACACTGAGGGCCACTGGGAATGGAGTCTCA
luSerLeuGluSerLeuAlaValProValAlaPheThrProValLysThrProValLeuG
||| ||| ||||||||| ||||||||||||
ysSerSerValAsnCysValValGlnAlaAlaPheThrSerValLysThrProThrGlnL
AAAGTTCAGTGAACTGTGTGGTGCAAGCAGCCTTCACATCTGTGAAGACTCCCACCCAGA
luGlnTrpGlnArgAsnGlyPheGlyGluAsnIleSerLeuAsnProAspLeuProHisG
||| ||| |||||||||||| |||||| |
ysGluCysGlnGlyAsnArgPheGlyGluAsnLeuAsnMetSerSerAsnLeuProValG
AGGAATGTCAGGGAAACAGGTTTGGGGAAAACCTGAATATGAGCTCTAATCTCCCAGTTC
lnProMetThrProGluArgGlnSerProHisThrTrpGlyThrArgGlyLysArgGluL
||||||||||||||||||||||| ||| |||||||||||||||||||||||||
lnProMetThrProGluArgGlnGlyProProMetTrpGlyThrArgGlyLysArgGluL
AACCAATGACTCCTGAAAGACAGGGTCCTCCCATGTGGGGAACACGTGGAAAGAGGGAGA
ysProAsp<-><->LeuAsnValLeuGlnLysThrCysValLysGluLysProTyrLysC
|| ||| |||||| ||||||||| |||||| ||| |
ysLeuAspSerLysLeuAsnAlaProGlnLysThrTyrAlaArgGluLysSerTyrArgC
AACTGGACTCAAAGTTAAATGCTCCACAGAAAACCTATGCAAGAGAGAAATCTTACAGAT
ysGlnGluCysGlyLysAlaPheSerHisSerSerAlaLeuIleGluHisHisArgThrH
||||||||||||||||| ||| ||||||||||||||||||||||||||||||||||
ysGlnGluCysGlyLysAspPheAsnHisSerSerAlaLeuIleGluHisHisArgThrH
GTCAGGAATGTGGAAAGGACTTTAATCATAGCTCAGCACTCATTGAACACCACCGAACGC
isThrGlyGluArgProTyrGluCysHisGluCysLeuLysGlyPheArgAsnSerSerA
|||||||||||||||||||| ||| |||||| ||||||||||||||||||||||
isThrGlyGluArgProTyrLysCysGlnGluCysGlyLysGlyPheArgAsnSerSerA
ACACAGGAGAGAGACCTTATAAATGTCAGGAATGTGGAAAAGGCTTCCGAAACAGCTCTG
laLeuThrLysHisGlnArgIleHisThrGlyGluLysProTyrLysCysThrGlnCysG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
laLeuThrLysHisGlnArgIleHisThrGlyGluLysProTyrLysCysThrGlnCysG
CACTTACCAAACACCAGAGAATCCACACTGGGGAAAAACCCTATAAATGCACTCAATGTG
lyArgThrPheAsnGlnIleAlaProLeuIleGlnHisGlnArgThrHisThrGlyGluL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lyArgThrPheAsnGlnIleAlaProLeuIleGlnHisGlnArgThrHisThrGlyGluL
GGAGGACCTTCAACCAAATTGCTCCACTGATCCAGCACCAGAGAACTCACACAGGTGAGA
ysProTyrGluCysSerGluCysGlyLysSerPheSerPheArgSerSerPheSerGlnH
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysProTyrGluCysSerGluCysGlyLysSerPheSerPheArgSerSerPheSerGlnH
AGCCCTATGAGTGCAGTGAGTGTGGGAAATCCTTCAGTTTTAGGTCTTCTTTCAGCCAGC
isGluArgThrHisThrGlyGluLysProTyrGluCysSerGluCysGlyLysAlaPheA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
isGluArgThrHisThrGlyGluLysProTyrGluCysSerGluCysGlyLysAlaPheA
ATGAGAGGACTCACACGGGTGAGAAGCCCTATGAGTGCAGTGAATGTGGGAAGGCCTTCC
rgGlnSerIleHisLeuThrGlnHisLeuArgIleHisThrGlyGluLysProTyrGlnC
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgGlnSerIleHisLeuThrGlnHisLeuArgIleHisThrGlyGluLysProTyrGlnC
GGCAGAGTATTCACCTCACACAACACCTACGAATCCACACTGGAGAGAAACCTTATCAGT
ysGlyGluCysGlyLysAlaPheSerHisSerSerSerLeuThrLysHisGlnArgIleH
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysGlyGluCysGlyLysAlaPheSerHisSerSerSerLeuThrLysHisGlnArgIleH
GTGGAGAGTGTGGCAAGGCTTTCAGCCACAGCTCATCCTTGACCAAACACCAGCGAATTC
isThrGlyGluLysProTyrGluCysHisGluCysGlyLysAlaPheThrGlnIleThrP
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
isThrGlyGluLysProTyrGluCysHisGluCysGlyLysAlaPheThrGlnIleThrP
ACACTGGAGAAAAGCCCTATGAGTGCCATGAGTGTGGGAAAGCCTTCACCCAGATCACGC
roLeuIleGlnHisGlnArgThrHisThrGlyGluLysProTyrGluCysGlyGluCysG
|||||||||||||||||||||||||||||||||||||||||||||||||| |||||||
roLeuIleGlnHisGlnArgThrHisThrGlyGluLysProTyrGluCysSerGluCysG
CACTGATTCAGCATCAGAGGACCCACACAGGAGAGAAGCCTTATGAGTGCAGTGAGTGTG
lyLysAlaPheSerGlnSerThrLeuLeuThrGluHisArgArgIleHisThrGlyGluL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
lyLysAlaPheSerGlnSerThrLeuLeuThrGluHisArgArgIleHisThrGlyGluL
GGAAGGCCTTTAGCCAGAGCACACTCCTGACTGAGCACCGGAGGATTCACACGGGTGAGA
ysProTyrGlyCysAsnGluCysGlyLysThrPheSerHisSerSerSerLeuSerGlnH
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysProTyrGlyCysAsnGluCysGlyLysThrPheSerHisSerSerSerLeuSerGlnH
AGCCATATGGATGCAATGAGTGTGGCAAAACCTTCAGTCACAGCTCTTCACTAAGCCAGC
isGluArgThrHisThrGlyGluLysProTyrGluCysSerGlnCysGlyLysAlaPheA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
isGluArgThrHisThrGlyGluLysProTyrGluCysSerGlnCysGlyLysAlaPheA
ATGAGCGGACACACACAGGAGAAAAGCCCTATGAGTGTAGTCAGTGTGGGAAGGCCTTCC
rgGlnSerThrHisLeuThrGlnHisGlnArgIleHisThrGlyGluLysProTyrGluC
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
rgGlnSerThrHisLeuThrGlnHisGlnArgIleHisThrGlyGluLysProTyrGluC
GGCAGAGCACACACCTCACTCAGCACCAGAGAATCCACACAGGGGAAAAACCCTATGAAT
ysAsnAspCysGlyLysAlaPheSerHisSerSerSerLeuThrLysHisGlnArgIleH
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysAsnAspCysGlyLysAlaPheSerHisSerSerSerLeuThrLysHisGlnArgIleH
GTAATGACTGTGGCAAGGCCTTCAGCCATAGCTCATCCCTAACAAAACATCAGCGGATCC
isThrGlyGluLysProTyrGluCysAsnGlnCysGlyArgAlaPheSerGlnLeuAlaP
||||||||||||||||||||||||||||| ||||||||||||||||||||||||||||
isThrGlyGluLysProTyrGluCysAsnGluCysGlyArgAlaPheSerGlnLeuAlaP
ACACTGGGGAGAAACCCTATGAATGTAATGAATGTGGCAGAGCCTTCAGCCAGCTTGCTC
roLeuIleGlnHisGlnArgIleHisThrGlyGluLysProTyrGluCysAsnGlnCysG
||||||||||||||||||||||||||||||||||||||||||||||||||||| |||
roLeuIleGlnHisGlnArgIleHisThrGlyGluLysProTyrGluCysAsnGluCysS
CCCTTATTCAGCATCAGAGGATCCACACAGGAGAGAAGCCCTATGAGTGTAATGAGTGTA
lyArgAlaPheSerGlnSerSerLeuLeuIleGluHisGlnArgIleHisThrLysGluL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
erArgAlaPheSerGlnSerSerLeuLeuIleGluHisGlnArgIleHisThrLysGluL
GCAGAGCCTTCAGCCAGAGCTCCCTTCTCATAGAACACCAGAGGATTCACACCAAGGAAA
ysProTyrGlyCysAsnGluCysGlyLysSerPheSerHisSerSerSerLeuSerGlnH
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysProTyrGlyCysAsnGluCysGlyLysSerPheSerHisSerSerSerLeuSerGlnH
AGCCCTATGGGTGCAATGAATGCGGGAAATCTTTTAGTCACAGCTCATCACTCAGCCAGC
isGluArgThrHisThrGlyGluLysProTyrGluCysHisAspCysGlyLysSerPheA
|||||||||||||||||||||||||||||||||||||| |||||||||||||||||||
isGluArgThrHisThrGlyGluLysProTyrGluCysGlnAspCysGlyLysSerPheA
ATGAAAGGACACACACTGGGGAAAAGCCCTATGAATGTCAGGATTGTGGAAAATCCTTCA
rgGlnSerThrHisLeuThrGlnHisArgArgIleHisThrGlyGluLysProTyrAlaC
|||||||||||||||||||||||||||||||||||||||||||||||||||||||| |
rgGlnSerThrHisLeuThrGlnHisArgArgIleHisThrGlyGluLysProTyrGluC
GGCAGAGCACCCACCTCACTCAGCACCGGAGAATCCACACAGGAGAGAAGCCGTATGAGT
ysArgAspCysGlyLysAlaPheThrHisSerSerSerLeuThrLysHisGlnArgThrH
|| ||||||||||||||||||||||||||||||||||||||||||||||||||||
ysGlyAsnCysGlyLysAlaPheThrHisSerSerSerLeuThrLysHisGlnArgThrH
GTGGGAACTGTGGGAAGGCCTTTACACACAGCTCCTCCCTTACCAAGCACCAGAGAACTC
isThrGly
||||||||
isThrGly
ATACTGGA
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