| Basic information |
| Official Symbol | TUBA1C |
| Description | tubulin, alpha 1c |
| Other Aliases | TUBA6, bcm948 |
| Other Description | alpha-tubulin 6; tubulin alpha-1C chain; tubulin alpha-6 chain; tubulin, alpha 6 |
| Mutation type | Insert and frame-shift 32-33:A-K^AC |
| Location | Scaffold145652_1:2631653 2578943 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| TUBA1C |
ATGACAGCCCAGTTTAATGGGGTGGAGGAGCATGGGAGGGATGTGTGCTT TGTGTGCTTGGAACTGGTTCCTTCAAATGGATCCTTTCTGAACTCACCGC AAAACATCTCTAACTGGATTCTTATTTACTTTACCAGAACACCTCAGGTC CCTGCGCTTTTTAACACATGCACATCCAGCAAAAGCAGAGGAGAACCTGG CTCTCTCTCAAAGCGTGAGTGCATCTCCATCCACGTCGGCCAGGCTGGTG TCCAGATCGGCAATGCCTGCTGGGAGCTCTACTGCCTGGAACACGGCATC CAGCCCGATGGCCAGATGCCAAGTGACAAGACCATTGGGGGAGGAGATGA CTCCTTCAACACCTTCTTCAGCGAGACGGGCGCCGGCAAGCATGTGCCCA GGGCCGTGTTTGTAGACCTGGAACCCACAGTCATCGATGAAGTTCGCACT GGCACCTACCGCCAGCTCTTCCACCCTGAGCAGCTCATCACAGGCAAGGA AGATGCTGCCAATAACTATGCCCGCGGGCACTACACCATCGGCAAGGAGA TCATCGACCTCGTCTTGGACAGAATTCGCAAGCTGGCTGACCAGTGCACA GGTCTGCAGGGCTTCTTGGTTTTCCACAGCTTTGGTGGGGGAACTGGTTC TGGCTTCCCCTCCCTGCTGATGGAGCGGCTCTCAGTGGATTATGGCAAGA AGTCCAAGCTGGAGTTCTCCATCTACCCAGCCCCCCAGGTCTCCACGGCT GTCGTTGAGCCCTACAACTCCATCCTCACCACCCACACCACCCTGGAGCA CTCTGACTGTGCCTTCATGGTAGACAACGAGGCCATCTATGACATCTGTC GTAGAAACCTCGACATTGAACGCCCAACCTACACTAACCTCAACCGCCTT ATTAGCCAGATTGTGTCCTCCATCACTGCTTCTCTTAGATTTGATGGAGC CCTGAATGTCGATCTGACAGAATTCCAGACCAACCTGGTGCCCTGTCCCC GCATCCACTTCTCTCTGGCCACATATGCCCCTGTCATCTCTGCTGAGAAA GCCTTCCATGAACAGCTTTCTGTAACAGAGATCAACAAGGCTTGCTTTGA GCCTGCCAACCAGATGGTGAAATGCGACCCTCGCCATGGTAAATACATGG CTTGTTGCCTGTTGTACCGTGGCGATGTGGTTCCCAAAGATGTCAATGCT GCCATTGCCACCATCAAGACCAAGCGCACCATCCAGTTTGTGGATTGGTG CCCCACTGGCTTTAAGGTTGGCATTAACTACCAGCCTCCCACTGTGGTGC CTGGGGGAGACCTGGCCAAGGTGCAGCGTGCTGTGTGCATGCTGAGCAAC ACCACAGCCATTGCTGAGGCCTGGGCTCGCCTGGACCACAAGTTTGACCT GATGTATGCCAAGCGTGCCTTCGTTCACTGGTACGTAGGTGAGGGGATGG AGGAAGGAGAGTTTTCTGAGGCCCGAGAGGACATGGCTGCCCTTGAGAAG GATTATGAGGAGGTTGGAGCAGACAGTGCTGAGGGGGAGGATGAGGGTGA AGAGTAT |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 519 | 1 | 519 | Insert and frame-shift 32-33:A-K^AC |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetThrAlaTrpPheAsnGlyValGluGluLeuGlyArgAspGluCysPheValCysLeu
||||||||| |||||||||||||||||| ||||||||| |||||||||||||||
MetThrAlaGlnPheAsnGlyValGluGluHisGlyArgAspValCysPheValCysLeu
ATGACAGCCCAGTTTAATGGGGTGGAGGAGCATGGGAGGGATGTGTGCTTTGTGTGCTTG
GluLeuAspProSerAsnGlySerPheLeuAsnAla--LysLeuTyrIleSerAsnTrpI
|||||| |||||||||||||||||||||||| ## |||||||||||||
GluLeuValProSerAsnGlySerPheLeuAsnSer##ProGlnAsnIleSerAsnTrpI
GAACTGGTTCCTTCAAATGGATCCTTTCTGAACTCAACCCGCAAAACATCTCTAACTGGA
leLeuIleTyrPheThrArgThrLeuGlnLeuProAlaProPheAsnThrCysThrSerS
||||||||||||||||||||||| ||| |||||| |||||||||||||||||||
leLeuIleTyrPheThrArgThrProGlnValProAlaLeuPheAsnThrCysThrSerS
TTCTTATTTACTTTACCAGAACACCTCAGGTCCCTGCGCTTTTTAACACATGCACATCCA
erLysSerArgGlyGluProGlyCysAspSerLys >>>> Target Intron 1 >>
||||||||||||||||||||||| |||||| 48446 bp
erLysSerArgGlyGluProGlySerLeuSerLys++
GCAAAAGCAGAGGAGAACCTGGCTCTCTCTCAAAGgt
>> ArgGluCysIleSerIleHisValGlyGlnAlaGlyValGlnIleGlyAsnAlaCy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||
++ArgGluCysIleSerIleHisValGlyGlnAlaGlyValGlnIleGlyAsnAlaCy
agCGTGAGTGCATCTCCATCCACGTCGGCCAGGCTGGTGTCCAGATCGGCAATGCCTG
sTrpGluLeuTyrCysLeuGluHisGlyIleGlnProAspGlyGlnMetProSerAspLy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sTrpGluLeuTyrCysLeuGluHisGlyIleGlnProAspGlyGlnMetProSerAspLy
CTGGGAGCTCTACTGCCTGGAACACGGCATCCAGCCCGATGGCCAGATGCCAAGTGACAA
sThrIleGlyGlyGlyAspAspSerPheAsnThrPhePheSerGluThrGlyAlaGlyLy
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sThrIleGlyGlyGlyAspAspSerPheAsnThrPhePheSerGluThrGlyAlaGlyLy
GACCATTGGGGGAGGAGATGACTCCTTCAACACCTTCTTCAGCGAGACGGGCGCCGGCAA
sHisValProArgAlaValPheValAspLeuGluProThrValIle{A} >>>> Targ
||||||||||||||||||||||||||||||||||||||||||||||{|}
sHisValProArgAlaValPheValAspLeuGluProThrValIle{A}++
GCATGTGCCCAGGGCCGTGTTTGTAGACCTGGAACCCACAGTCATC{G}gt
et Intron 2 >>>> {sp}GluValArgThrGlyThrTyrArgGlnLeuPheHisPr
184 bp {||}||||||||||||||||||||||||||||||||||||||
++{sp}GluValArgThrGlyThrTyrArgGlnLeuPheHisPr
ag{AT}GAAGTTCGCACTGGCACCTACCGCCAGCTCTTCCACCC
oGluGlnLeuIleThrGlyLysGluAspAlaAlaAsnAsnTyrAlaArgGlyHisTyrTh
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
oGluGlnLeuIleThrGlyLysGluAspAlaAlaAsnAsnTyrAlaArgGlyHisTyrTh
TGAGCAGCTCATCACAGGCAAGGAAGATGCTGCCAATAACTATGCCCGCGGGCACTACAC
rIleGlyLysGluIleIleAspLeuValLeuAspArgIleArgLysLeu >>>> Targ
|||||||||||||||||||||||||||||||||||||||||||||||||
rIleGlyLysGluIleIleAspLeuValLeuAspArgIleArgLysLeu++
CATCGGCAAGGAGATCATCGACCTCGTCTTGGACAGAATTCGCAAGCTGgt
et Intron 3 >>>> AlaAspGlnCysThrGlyLeuGlnGlyPheLeuValPheHis
2522 bp ||||||||||||||||||||||||||||||||||||||||||
++AlaAspGlnCysThrGlyLeuGlnGlyPheLeuValPheHis
agGCTGACCAGTGCACAGGTCTGCAGGGCTTCTTGGTTTTCCAC
SerPheGlyGlyGlyThrGlySerGlyPheThrSerLeuLeuMetGluArgLeuSerVal
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
SerPheGlyGlyGlyThrGlySerGlyPheProSerLeuLeuMetGluArgLeuSerVal
AGCTTTGGTGGGGGAACTGGTTCTGGCTTCCCCTCCCTGCTGATGGAGCGGCTCTCAGTG
AspTyrGlyLysLysSerLysLeuGluPheSerIleTyrProAlaProGlnValSerThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AspTyrGlyLysLysSerLysLeuGluPheSerIleTyrProAlaProGlnValSerThr
GATTATGGCAAGAAGTCCAAGCTGGAGTTCTCCATCTACCCAGCCCCCCAGGTCTCCACG
AlaValValGluProTyrAsnSerIleLeuThrThrHisThrThrLeuGluHisSerAsp
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaValValGluProTyrAsnSerIleLeuThrThrHisThrThrLeuGluHisSerAsp
GCTGTCGTTGAGCCCTACAACTCCATCCTCACCACCCACACCACCCTGGAGCACTCTGAC
CysAlaPheMetValAspAsnGluAlaIleTyrAspIleCysArgArgAsnLeuAspIle
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
CysAlaPheMetValAspAsnGluAlaIleTyrAspIleCysArgArgAsnLeuAspIle
TGTGCCTTCATGGTAGACAACGAGGCCATCTATGACATCTGTCGTAGAAACCTCGACATT
GluArgProThrTyrThrAsnLeuAsnArgLeuIleSerGlnIleValSerSerIleThr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluArgProThrTyrThrAsnLeuAsnArgLeuIleSerGlnIleValSerSerIleThr
GAACGCCCAACCTACACTAACCTCAACCGCCTTATTAGCCAGATTGTGTCCTCCATCACT
AlaSerLeuArgPheAspGlyAlaLeuAsnValAspLeuThrGluPheGlnThrAsnLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaSerLeuArgPheAspGlyAlaLeuAsnValAspLeuThrGluPheGlnThrAsnLeu
GCTTCTCTTAGATTTGATGGAGCCCTGAATGTCGATCTGACAGAATTCCAGACCAACCTG
ValProTyrProArgIleHisPheProLeuAlaThrTyrAlaProValIleSerAlaGlu
|||||| ||||||||||||||| |||||||||||||||||||||||||||||||||
ValProCysProArgIleHisPheSerLeuAlaThrTyrAlaProValIleSerAlaGlu
GTGCCCTGTCCCCGCATCCACTTCTCTCTGGCCACATATGCCCCTGTCATCTCTGCTGAG
LysAlaTyrHisGluGlnLeuThrValAlaGluIleThrAsnAlaCysPheGluProAla
|||||| |||||||||||| ||| |||||| ||||||||||||||||||
LysAlaPheHisGluGlnLeuSerValThrGluIleAsnLysAlaCysPheGluProAla
AAAGCCTTCCATGAACAGCTTTCTGTAACAGAGATCAACAAGGCTTGCTTTGAGCCTGCC
AsnGlnMetValLysCysAspProArgHisGlyLysTyrMetAlaCysCysLeuLeuTyr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AsnGlnMetValLysCysAspProArgHisGlyLysTyrMetAlaCysCysLeuLeuTyr
AACCAGATGGTGAAATGCGACCCTCGCCATGGTAAATACATGGCTTGTTGCCTGTTGTAC
ArgGlyAspValValProLysAspValAsnAlaAlaIleAlaThrIleLysThrLysArg
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ArgGlyAspValValProLysAspValAsnAlaAlaIleAlaThrIleLysThrLysArg
CGTGGCGATGTGGTTCCCAAAGATGTCAATGCTGCCATTGCCACCATCAAGACCAAGCGC
ThrIleGlnPheValAspTrpCysProThrGlyPheLysValGlyIleAsnTyrGlnPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrIleGlnPheValAspTrpCysProThrGlyPheLysValGlyIleAsnTyrGlnPro
ACCATCCAGTTTGTGGATTGGTGCCCCACTGGCTTTAAGGTTGGCATTAACTACCAGCCT
ProThrValValProGlyGlyAspLeuAlaLysValGlnArgAlaValCysMetLeuSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ProThrValValProGlyGlyAspLeuAlaLysValGlnArgAlaValCysMetLeuSer
CCCACTGTGGTGCCTGGGGGAGACCTGGCCAAGGTGCAGCGTGCTGTGTGCATGCTGAGC
AsnThrThrAlaValAlaGluAlaTrpAlaArgLeuAspHisLysPheAspLeuMetTyr
|||||||||||| |||||||||||||||||||||||||||||||||||||||||||||
AsnThrThrAlaIleAlaGluAlaTrpAlaArgLeuAspHisLysPheAspLeuMetTyr
AACACCACAGCCATTGCTGAGGCCTGGGCTCGCCTGGACCACAAGTTTGACCTGATGTAT
AlaLysArgAlaPheValHisTrpTyrValGlyGluGlyMetGluGluGlyGluPheSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
AlaLysArgAlaPheValHisTrpTyrValGlyGluGlyMetGluGluGlyGluPheSer
GCCAAGCGTGCCTTCGTTCACTGGTACGTAGGTGAGGGGATGGAGGAAGGAGAGTTTTCT
GluAlaArgGluAspMetAlaAlaLeuGluLysAspTyrGluGluValGlyAlaAspSer
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
GluAlaArgGluAspMetAlaAlaLeuGluLysAspTyrGluGluValGlyAlaAspSer
GAGGCCCGAGAGGACATGGCTGCCCTTGAGAAGGATTATGAGGAGGTTGGAGCAGACAGT
AlaAspGlyGluAspGluGlyGluGluTyr
||| ||||||||||||||||||||||||
AlaGluGlyGluAspGluGlyGluGluTyr
GCTGAGGGGGAGGATGAGGGTGAAGAGTAT
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