| Basic information |
| Official Symbol | PGPEP1L |
| Description | pyroglutamyl-peptidase I-like |
| Other Aliases | NA |
| Other Description | pyroglutamyl-peptidase 1-like protein |
| Mutation type | Insert and frame-shift 174-175:V-G^A |
| Location | Scaffold138490_1:530759 527665 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| PGPEP1L |
CTGCAGGAGCTCTCCCAGCTGGGCCTGGGGAACGACGTGGAGGTGGAACT GCGGACCCTTCAGTTGCCTGTGGATTACAGGGAGGCTGAGAAGAGGGTTA CCAGAATCTGGAAAGATCTACGACCTCACCTCGTGGTGCACGTGGGTGTA GACGCCTCCGCCAAGGTCATCTTTCTGGAACAGTGCGGCAAGAACCGAGG CTACGCGGACGCCGACATCCGGGGTTTCCGGCCAGAGGGCGGTGTGTGCA TCCCTGGTGGCCCGGAAGTGATCGAGTCCAGGGTCAGCATGAAGGCAATC TGCAAGCGTGTTGGAGTGCAAGAGGTCGAAGTGGCTTTTTCCCGCGACGC CGGCAGATACGTTTGCGATTACACCTATTACCTGTCTCTACGTCGTGGAC ACGGCTGTGCAGCCCTCATCCATGTCCCTCCGCTGTCGCAAGGGCTCCCG GCCAGCCTGTTGGGAAAAGCCTTGCAAGTCATCATCCGGGAAATGCTGGA AGAGACCGGCAAGCCCAGGTTCAAAGCCTGGTTCACAGAAAACTCAACCC CAGCGATTCTGCCGAAGGGA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 196 | 6 | 195 | Insert and frame-shift 174-175:V-G^A |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
LeuValGluLeuSerLysLeuGlyLeuGlyAsnGluThrValValGlnLeuArgThrLeuGl
||| ||||||||| ||||||||||||||| ||| ||||||||||||
LeuGlnGluLeuSerGlnLeuGlyLeuGlyAsnAspValGluValGluLeuArgThrLeuGl
CTGCAGGAGCTCTCCCAGCTGGGCCTGGGGAACGACGTGGAGGTGGAACTGCGGACCCTTCA
uLeuProValAspTyrArgGluAlaLysArgArgValThrGlyIleTrpGluAspHisGlnP
|||||||||||||||||||||||| ||||||||| |||||| ||| |
nLeuProValAspTyrArgGluAlaGluLysArgValThrArgIleTrpLysAspLeuArgP
GTTGCCTGTGGATTACAGGGAGGCTGAGAAGAGGGTTACCAGAATCTGGAAAGATCTACGAC
roGln >>>> Target Intron 1 >>>> LeuValValHisValGlyMetAspThrA
|| 1331 bp |||||||||||||||||| |||
roHis++ ++LeuValValHisValGlyValAspAlaS
CTCACgt agCTCGTGGTGCACGTGGGTGTAGACGCCT
laAlaLysAlaIleIleLeuGluGlnSerGlyLysAsnGlnGlyTyrArgAspAlaAspIle
|||||| ||| ||||||||| ||||||||| |||||| ||||||||||||
erAlaLysValIlePheLeuGluGlnCysGlyLysAsnArgGlyTyrAlaAspAlaAspIle
CCGCCAAGGTCATCTTTCTGGAACAGTGCGGCAAGAACCGAGGCTACGCGGACGCCGACATC
ArgSerPheTrpProGluGlyGlyValCysLeuProGlySerProAspValLeuGluSerGl
||| ||| |||||||||||||||||| |||||| ||| ||| ||||||
ArgGlyPheArgProGluGlyGlyValCysIleProGlyGlyProGluValIleGluSerAr
CGGGGTTTCCGGCCAGAGGGCGGTGTGTGCATCCCTGGTGGCCCGGAAGTGATCGAGTCCAG
yValCysMetLysAlaValCysLysArgValAlaValGluGlyValAspValIlePheSerA
||| ||||||||| |||||||||||| ||| ||| ||| |||||||
gValSerMetLysAlaIleCysLysArgValGlyValGlnGluValGluValAlaPheSerA
GGTCAGCATGAAGGCAATCTGCAAGCGTGTTGGAGTGCAAGAGGTCGAAGTGGCTTTTTCCC
rgAspAlaGly{Ar} >>>> Target Intron 2 >>>> {g}TyrValCysAspTyr
|||||||||||{||} 1193 bp {|}|||||||||||||||
rgAspAlaGly{Ar}++ ++{g}TyrValCysAspTyr
GCGACGCCGGC{AG}gt ag{A}TACGTTTGCGATTAC
ThrTyrTyrLeuSerLeuHisHisGlyLysGlyCysAlaAlaLeuIleHisValProProLe
|||||||||||||||||| ||| ||||||||||||||||||||||||||||||||
ThrTyrTyrLeuSerLeuArgArgGlyHisGlyCysAlaAlaLeuIleHisValProProLe
ACCTATTACCTGTCTCTACGTCGTGGACACGGCTGTGCAGCCCTCATCCATGTCCCTCCGCT
uSerArgGlyLeuProAlaSerLeuLeuGlyArgAlaLeuArgValIleIleGlnGluMetL
|||| |||||||||||||||||||||||| |||||| ||||||||| |||||||
uSerGlnGlyLeuProAlaSerLeuLeuGlyLysAlaLeuGlnValIleIleArgGluMetL
GTCGCAAGGGCTCCCGGCCAGCCTGTTGGGAAAAGCCTTGCAAGTCATCATCCGGGAAATGC
euGluGluVal-GlyLysProLysHisArgAlaGlnPheGluGluAsnSerThrMetValLe
|||||||| #||||||||| ||| ||| ||||||||||||
euGluGluThr#GlyLysProArgPheLysAlaTrpPheThrGluAsnSerThrProAlaIl
TGGAAGAGACCAGGCAAGCCCAGGTTCAAAGCCTGGTTCACAGAAAACTCAACCCCAGCGAT
uProAlaLysGly
||||||
eLeuProLysGly
//
|