| Basic information |
| Official Symbol | EMR3 |
| Description | egf-like module containing, mucin-like, hormone receptor-like 3 |
| Other Aliases | UNQ683/PRO1562 |
| Other Description | EGF-like module receptor 3; EGF-like module-containing mucin-like hormone receptor-like 3; egf-like module-containing mucin-like receptor 3 |
| Mutation type | Delete and frame-shift 633:G->GC |
| Location | Scaffold138060_1:2066430 2089207 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| EMR3 |
GAAGATACCTGTCCTCTATGCCCCGTAAACTCTTCCTGTGTCAATGGAACTTACTGTACC TGTAACTCCGGGTTCACTTCTAGATCTGGACAGATATTCTTCACATTCATCTTAGAGACA TGTAACGTTAATGAATGCCAGCCACCCACTAGCATATATTGTGGCGTCCATGCTGAATGT CATAACACAGAAGGAAGTTTCTACTGTAGCTGTGTCCCTGGATACCAGCTCCGCTCGGGA GGCGAAAAATTCAGGTCGGCCAGTGAGAACACCTGTCAGAGTAAGAAAATTCTTGTCTTC TTAATGTCTTTAAAGTTGCAAAAGGTCATTAACAAATTCGAGTCACTTCTCACCAATGAG ACTTTATGGCAAACAGGAGAGAAGCAAGAAATCGCATCTGCGGCCACTTCTATCCTCCAG AATGTGGAATCAAACGTTCTAGAAACTGCTCTGAAAGCCCCACAGCAAGAAGTGCAGAAA ATCCAAAACAATACACTGGTTGAAACTCGAGTGGTTTCCAATAATTGCTCTGATGAAAGA AAGATATTTGACCTCAACGTCCAAATGAACACCATGGACATCCATTGCAATGACATCATC CAGGGAAACATACAACCCAGTGCAGTCGCCTTTATTGCATATTCTTCCCTTGGGAACATC ATAAATGCAACCTTCTTTGAAAACTTGGATGAGAAAGATCGGGTTTACCTGAACTCCCAG GTAGTGAGTGCTGCTATCGGACCTGAAAGAAACATGTCTCTCTCCACACCTGTTAATATG ACTCTGCAGCATCTGAAGATGAATCCAAGTAGCAAAAAGGCCTTCTGTGTGTACTGGAAA AGCACAGGCGGGGGCGGCCACTGGTCTAGGGATGGCTGCTTCCTCGTGCAAATGAACACA AGCCACACCACATGCAGCTCCACCCACCTGTCCAGTTTCGCCGTTCTCATGGCCTTCACC AGCCAGGACGAGGACCCTGTGCTGACCATCATCACCTACGTGGGGCTGGGCCTGTCTCTG CTGTGCCTCTTCCTGGCAGCCCTCACCTTCCTCCTGTGCAGAACCATCCAGAACATCAGC ACCTCCCTGCACCTGCAGCTCTCGCTCTGCCTCTTCCTGGCCCACCTCCTCTTCCTCACG GCCATCGACCAAACCGAACCCGAGGTGCTGTGTGCCGTCATCGCGGGAGCCTTGCACTAC CTGTACCTGGCCTCCTTCACCTGGATGCTGCTGGAGGGCCTGCACCTGCTCCTCACCGCG CGGAACCTCATGGTGGTCAACTACTCCAGCGTGAACAGATTCATGAAGCGGCTCATGTAC CCTGTGGGTTATGGAGTCCCCGCTGTGGTTGTGGCTGTCTCTGCAGGAGTCAGGCCTGGC CTTTACGGAACACCTGCCTGCTGGCTCCGCCTGGACCACGGATTCATCTGGGTCTTCCTT GGTCCTGTCTGTGTCATTATCTGTGTGAATTTCTTATTTTTTCTCTTGGTCCTTTGGATT TTGAAAAGGAAACTTTCCTCCCTCAACAGTGATGTGTCAACCATTCAGAACACAATGCTG ACGTTCAAAGCACTGGCTCAGCTCTTCATCTTGGGCTGCACCTGGTGTCTGGGCCTCCTG CAGGTGGGTCCAGGTGCCCAGGTCATGGCCTATCTCTTCACCATCATCAACACCCTGCAG GGAGTCTTCATCTTCCTGGTCTACTGCCTTCTCAGCCAACAGGTAAACACTGACCACTTT AAATGGTATCGAGAAGCCATGAAATCCAAATTCGAGTCTGAGACGTATACACTTTCCAGC AAGTCTGCCCTGACTCAAAGCCC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 652 | 25 | 638 | Delete and frame-shift 633:G->GC |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
LysThrSerCysAlaLysCysProProAsnAlaSerCysValAsnAsnThrHisCysThr
||| |||||| ||| |||||||||||| ||| ||||||
GluAspThrCysProLeuCysProValAsnSerSerCysValAsnGlyThrTyrCysThr
GAAGATACCTGTCCTCTATGCCCCGTAAACTCTTCCTGTGTCAATGGAACTTACTGTACC
CysAsnHisGlyTyrThrSerGlySerGlyGlnLysLeuPheThrPheProLeuGluThr
|||||| ||| |||||| ||||||||| ||||||||| |||||||||
CysAsnSerGlyPheThrSerArgSerGlyGlnIlePhePheThrPheIleLeuGluThr
TGTAACTCCGGGTTCACTTCTAGATCTGGACAGATATTCTTCACATTCATCTTAGAGACA
CysAsn{A} >>>> Target Intron 1 >>>> {sp}IleAsnGluCysThrPro
||||||{|} 555 bp {||} ||||||||| |||
CysAsn{A}++ ++{sp}ValAsnGluCysGlnPro
TGTAAC{G}gt ag{AC}GTTAATGAATGCCAGCCA
ProTyrSerValTyrCysGlyPheAsnAlaValCysTyrAsnValGluGlySerPheTyr
||| ||| ||||||||| ||| ||| ||| |||||||||||||||
ProThrSerIleTyrCysGlyValHisAlaGluCysHisAsnThrGluGlySerPheTyr
CCCACTAGCATATATTGTGGCGTCCATGCTGAATGTCATAACACAGAAGGAAGTTTCTAC
CysGlnCysValProGlyTyrArgLeuHisSerGlyAsnGluGlnPheSerAsnSerAsn
||| ||||||||||||||| ||| |||||| ||| |||
CysSerCysValProGlyTyrGlnLeuArgSerGlyGlyGluLysPheArgSerAlaSer
TGTAGCTGTGTCCCTGGATACCAGCTCCGCTCGGGAGGCGAAAAATTCAGGTCGGCCAGT
GluAsnThrCysGlnAspThrThrSerSerLysThrThr{G} >>>> Target Intr
||||||||||||||| { } 6034 bp
GluAsnThrCysGlnSerLysLysIleLeuValPheLeu{V}++
GAGAACACCTGTCAGAGTAAGAAAATTCTTGTCTTCTTA{G}gt
on 2 >>>> {lu}GlyArgLysGluLeuGlnLysIleValAspLysPheGluSerLeu
{ } ||||||||| |||||||||||||||
--{al}MetSerLeuLysLeuGlnLysValIleAsnLysPheGluSerLeu
tt{TA}ATGTCTTTAAAGTTGCAAAAGGTCATTAACAAATTCGAGTCACTT
LeuThrAsnGlnThrLeuTrpArgThrGluGlyArgGlnGluIleSerSerThrAlaThr
||||||||| ||||||||| ||| ||||||||| ||| ||||||
LeuThrAsnGluThrLeuTrpGlnThrGlyGluLysGlnGluIleAlaSerAlaAlaThr
CTCACCAATGAGACTTTATGGCAAACAGGAGAGAAGCAAGAAATCGCATCTGCGGCCACT
ThrIleLeuArgAspValGluSerLysValLeuGluThrAlaLeuLysAspProGluGln
|||||| ||||||||| ||||||||||||||||||||| ||| |||
SerIleLeuGlnAsnValGluSerAsnValLeuGluThrAlaLeuLysAlaProGlnGln
TCTATCCTCCAGAATGTGGAATCAAACGTTCTAGAAACTGCTCTGAAAGCCCCACAGCAA
LysValLeuLysIleGlnAsnAspSerVal{A} >>>> Target Intron 3 >>>>
||| |||||||||||| {|} 1236 bp
GluValGlnLysIleGlnAsnAsnThrLeu{A}++
GAAGTGCAGAAAATCCAAAACAATACACTG{G}gt
{la}IleGluThrGlnAlaIleThrAspAsnCysSerGluGluArgLysThrPheAsn
{||} |||||| ||||||||| ||||||||| |||
++{la}ValGluThrArgValValSerAsnAsnCysSerAspGluArgLysIlePheAsp
ag{CT}GTTGAAACTCGAGTGGTTTCCAATAATTGCTCTGATGAAAGAAAGATATTTGAC
LeuAsnValGlnMetAsnSerMetAspIleArgCysSerAspIleIleGlnGlyAspThr
|||||||||||||||||| ||||||||| ||| |||||||||||||||
LeuAsnValGlnMetAsnThrMetAspIleHisCysAsnAspIleIleGlnGlyAsnIle
CTCAACGTCCAAATGAACACCATGGACATCCATTGCAATGACATCATCCAGGGAAACATA
Gln{G} >>>> Target Intron 4 >>>> {ly}ProSerAlaIleAlaPheIle
|||{|} 295 bp {||}||||||||| |||||||||
Gln{G}++ ++{ly}ProSerAlaValAlaPheIle
CAA{G}gt ag{GC}CCCAGTGCAGTCGCCTTTATT
SerTyrSerSerLeuGlyAsnIleIleAsnAlaThrPhePheGluGluMetAspLysLys
|||||||||||||||||||||||||||||||||||||||||| ||| |||
AlaTyrSerSerLeuGlyAsnIleIleAsnAlaThrPhePheGluAsnLeuAspGluLys
GCATATTCTTCCCTTGGGAACATCATAAATGCAACCTTCTTTGAAAACTTGGATGAGAAA
AspGlnValTyrLeuAsnSerGlnValValSerAlaAlaIleGlyProLysArgAsnVal
||| |||||||||||||||||||||||||||||||||||||||||| ||||||
AspArgValTyrLeuAsnSerGlnValValSerAlaAlaIleGlyProGluArgAsnMet
GATCGGGTTTACCTGAACTCCCAGGTAGTGAGTGCTGCTATCGGACCTGAAAGAAACATG
SerLeuSerLysSerValThrLeuThrPheGlnHisValLys >>>> Target Intr
||||||||| ||| ||| |||||| ||| 1085 bp
SerLeuSerThrProValAsnMetThrLeuGlnHisLeuLys++
TCTCTCTCCACACCTGTTAATATGACTCTGCAGCATCTGAAGgt
on 5 >>>> MetThrProSerThrLysLysValPheCysValTyrTrpLysSerThrG
||| |||||| |||||| |||||||||||||||||||||||||
++MetAsnProSerSerLysLysAlaPheCysValTyrTrpLysSerThrG
agATGAATCCAAGTAGCAAAAAGGCCTTCTGTGTGTACTGGAAAAGCACAG
lyGlnGlySerGlnTrpSerArgAspGlyCysPheLeuIleHisValAsnLysSerHisT
|| ||| |||||||||||||||||||||||| ||| |||||||
lyGlyGlyGlyHisTrpSerArgAspGlyCysPheLeuValGlnMetAsnThrSerHisT
GCGGGGGCGGCCACTGGTCTAGGGATGGCTGCTTCCTCGTGCAAATGAACACAAGCCACA
hrMetCysAsnCysSerHisLeuSerSerPheAlaValLeuMetAlaLeuThrSerGln
|| ||| |||||||||||||||||||||||||||||| |||||||||
hrThrCysSerSerThrHisLeuSerSerPheAlaValLeuMetAlaPheThrSerGln+
CCACATGCAGCTCCACCCACCTGTCCAGTTTCGCCGTTCTCATGGCCTTCACCAGCCAGg
>>>> Target Intron 6 >>>> GluGluAspProValLeuThrValIleThrTy
2594 bp |||||||||||||||||| ||||||||
+ ++AspGluAspProValLeuThrIleIleThrTy
t agGACGAGGACCCTGTGCTGACCATCATCACCTA
rValGlyLeuSerValSerLeuLeuCysLeuLeuLeuAlaAlaLeuThrPheLeuLeuCy
|||||||||| ||||||||||||||| ||||||||||||||||||||||||||
rValGlyLeuGlyLeuSerLeuLeuCysLeuPheLeuAlaAlaLeuThrPheLeuLeuCy
CGTGGGGCTGGGCCTGTCTCTGCTGTGCCTCTTCCTGGCAGCCCTCACCTTCCTCCTGTG
sLysAlaIleArgAsnThrSerThrSerLeuHisLeuGlnLeuSerLeuCysLeuPheLe
| ||| ||| |||||||||||||||||||||||||||||||||||||||||
sArgThrIleGlnAsnIleSerThrSerLeuHisLeuGlnLeuSerLeuCysLeuPheLe
CAGAACCATCCAGAACATCAGCACCTCCCTGCACCTGCAGCTCTCGCTCTGCCTCTTCCT
uAlaHisLeuLeuPheLeuValGlyIleAspArgThrGluProLys >>>> Target
||||||||||||||||||| |||||| ||||||||| 168
uAlaHisLeuLeuPheLeuThrAlaIleAspGlnThrGluProGlu++
GGCCCACCTCCTCTTCCTCACGGCCATCGACCAAACCGAACCCGAGgt
Intron 7 >>>> ValLeuCysSerIleIleAlaGlyAlaLeuHisTyrLeuTyrLeu
6 bp ||||||||| ||||||||||||||||||||||||||||||
++ValLeuCysAlaValIleAlaGlyAlaLeuHisTyrLeuTyrLeu
agGTGCTGTGTGCCGTCATCGCGGGAGCCTTGCACTACCTGTACCTG
AlaAlaPheThrTrpMetLeuLeuGluGlyValHisLeuPheLeuThrAlaArgAsnLeu
||| |||||||||||||||||||||||| |||||| ||||||||||||||||||
AlaSerPheThrTrpMetLeuLeuGluGlyLeuHisLeuLeuLeuThrAlaArgAsnLeu
GCCTCCTTCACCTGGATGCTGCTGGAGGGCCTGCACCTGCTCCTCACCGCGCGGAACCTC
ThrValValAsnTyrSerSerIleAsnArgLeuMetLysTrpIleMetPheProValGly
|||||||||||||||||| |||||| |||||| ||| |||||||||
MetValValAsnTyrSerSerValAsnArgPheMetLysArgLeuMetTyrProValGly
ATGGTGGTCAACTACTCCAGCGTGAACAGATTCATGAAGCGGCTCATGTACCCTGTGGGT
TyrGlyValProAlaValThrValAlaIleSerAlaAlaSerTrpProHisLeuTyrGly
|||||||||||||||||| |||||| |||||| ||| |||||||||
TyrGlyValProAlaValValValAlaValSerAlaGlyValArgProGlyLeuTyrGly
TATGGAGTCCCCGCTGTGGTTGTGGCTGTCTCTGCAGGAGTCAGGCCTGGCCTTTACGGA
ThrAlaAsp{Ar} >>>> Target Intron 8 >>>> {g}CysTrpLeuHisLeu
||| {||} 1956 bp {|}||||||||| |||
ThrProAla{Ar}++ ++{g}CysTrpLeuArgLeu
ACACCTGCC{CG}gt ag{A}TGCTGGCTCCGCCTG
AspGlnGlyPheMetTrpSerPheLeuGlyProValCysAlaIlePheSer >>>> Ta
||| |||||| ||| |||||||||||||||||| |||
AspHisGlyPheIleTrpValPheLeuGlyProValCysValIleIleCys++
GACCACGGATTCATCTGGGTCTTCCTTGGTCCTGTCTGTGTCATTATCTGTgt
rget Intron 9 >>>> AlaAsnLeuValLeuPheIleLeuValPheTrpIleLeuL
597 bp ||| ||| |||||| ||||||||||
++ValAsnPheLeuPhePheLeuLeuValLeuTrpIleLeuL
agGTGAATTTCTTATTTTTTCTCTTGGTCCTTTGGATTTTGA
ysArgLysLeuSerSerLeuAsnSerGluValSerThrIleGlnAsnThr{Ar} >>>>
|||||||||||||||||||||||||| |||||||||||||||||||||{||}
ysArgLysLeuSerSerLeuAsnSerAspValSerThrIleGlnAsnThr{Ar}++
AAAGGAAACTTTCCTCCCTCAACAGTGATGTGTCAACCATTCAGAACACA{AG}gt
Target Intron 10 >>>> {g}MetLeuAlaPheLysAlaThrAlaGlnLeuPhe
2037 bp {|}|||||| ||||||||| ||||||||||||
++{g}MetLeuThrPheLysAlaLeuAlaGlnLeuPhe
ag{G}ATGCTGACGTTCAAAGCACTGGCTCAGCTCTTC
IleLeuGlyCysThrTrpCysLeuGlyLeuLeuGlnValGlyProAlaAlaGlnValMet
||||||||||||||||||||||||||||||||||||||||||||| ||||||||||||
IleLeuGlyCysThrTrpCysLeuGlyLeuLeuGlnValGlyProGlyAlaGlnValMet
ATCTTGGGCTGCACCTGGTGTCTGGGCCTCCTGCAGGTGGGTCCAGGTGCCCAGGTCATG
AlaTyrLeuPheThrIleIleAsnSerLeuGlnGlyPhePheIlePheLeuValTyrCys
|||||||||||||||||||||||| ||||||||| |||||||||||||||||||||
AlaTyrLeuPheThrIleIleAsnThrLeuGlnGlyValPheIlePheLeuValTyrCys
GCCTATCTCTTCACCATCATCAACACCCTGCAGGGAGTCTTCATCTTCCTGGTCTACTGC
LeuLeuSerGlnGlnValGlnLysGlnTyrGln >>>> Target Intron 11 >>>
|||||||||||||||||| 2861 bp
LeuLeuSerGlnGlnValAsnThrAspHisPhe-+
CTTCTCAGCCAACAGGTAAACACTGACCACTTTtt
> LysTrpPheArgGluIleValLysSerLysSerGluSerGluThrTyrThrLeuSer
|||||| |||||| ||||||||| ||||||||||||||||||||||||
-+LysTrpTyrArgGluAlaMetLysSerLysPheGluSerGluThrTyrThrLeuSer
ggAAATGGTATCGAGAAGCCATGAAATCCAAATTCGAGTCTGAGACGTATACACTTTCC
SerLysMetGlyProAspSerLysPro
|||||| |||||||||||||||
SerLysSer---ProAspSerLysPro
AGCAAGTCTGC#CCTGACTCAAAGCCC
//
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