| Basic information |
| Official Symbol | DNAJC4 |
| Description | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| Other Aliases | DANJC4, HSPF2, MCG18 |
| Other Description | dnaJ homolog subfamily C member 4; dnaJ-like protein HSPF2; heat shock 40kD protein 2; multiple endocrine neoplasia type 1 candidate protein number 18 |
| Mutation type | Insert and frame-shift 212-213:F-C^C |
| Location | Scaffold000273_1:969470 972372 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| DNAJC4 |
ATGCCACCCCTGTTGTCCCTGCACCTGTGCCGGCTGTGGCTCCGCAGCCC CCCTACACGGCTCCTCGGAGCCGGCCGGGCAGCGAGGTCTGGCCCCAGTA ATTATTATGAACTGTTGGGGGTACATCCTGGTGCCAGTCCTGAAGAAGTT AAGCGAGCTTTCTTCACCAAGTCCAAAGAGCTGCATCCTGACCGGGACCC TGGGAACCCAGCCCTGCACAGCCGCTTTGTGGAGCTGAATGAGGCATACC ACGTGCTCAGCCGTGAGCAGAGCCGCCGTAGCTATGACCACCAGCTCCGC TCAGCCAGTCCCCCAAGGCCTCCAGGAACCACAGCCCACCCCAACTCTGC CAAACAGACACACAGCAGCTCCTGGACACATCCCAATGCACATTACTGGG CCCAGTTTCATGATGTGAGGCCACAGGGGGCCTGGGCAAGGCAGCAGCAG CACAAGCACAACCAGCGTGTGCTGGGGTACTGCCTTCTGCTCATGCTGGC AGGCATGGGCCTGCACTACGTGGCCTTCAGAAAGTTGGAGCAGGTACACC GCAGCTTCATGGATGAAAAGGATCGGATCATCACAGCCATCTACAACGAC ACACGGGCACGGGCCAGGTCTGTCTGCTCCATCTGCCCCCTGCCCCCTGC TCCTGGTACCATTCTCCAAGATCCTGACCCAGACACCCAGGTTCTCTCTC CTCCAGGGCCAACAGAGCCAGGCTCCAGCAGGAGC |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 249 | 1 | 246 | Insert and frame-shift 212-213:F-C^C |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
MetProProLeuLeuProLeuArgLeuCysArgLeuTrpProArgAsnProProSerArgLe
||||||||||||||| ||| ||||||||||||||| ||| |||||| |||||
MetProProLeuLeuSerLeuHisLeuCysArgLeuTrpLeuArgSerProProThrArgLe
ATGCCACCCCTGTTGTCCCTGCACCTGTGCCGGCTGTGGCTCCGCAGCCCCCCTACACGGCT
uLeuGlyAlaAlaAlaGlyGln >>>> Target Intron 1 >>>> ArgSerArgPr
|||||||||| 918 bp |||||| ||
uLeuGlyAlaGlyArgAlaAla++ +-ArgSerGlyPr
CCTCGGAGCCGGCCGGGCAGCGgt acAGGTCTGGCCC
oSerThrTyrTyrGluLeuLeuGlyValHisProGlyAlaSerThrGluGluValLysArgA
|||| |||||||||||||||||||||||||||||||||||| ||||||||||||||||
oSerAsnTyrTyrGluLeuLeuGlyValHisProGlyAlaSerProGluGluValLysArgA
CAGTAATTATTATGAACTGTTGGGGGTACATCCTGGTGCCAGTCCTGAAGAAGTTAAGCGAG
laPhePheSerLysSerLysGlu >>>> Target Intron 2 >>>> LeuHisProA
|||||||| |||||||||||| 495 bp ||||||||||
laPhePheThrLysSerLysGlu++ ++LeuHisProA
CTTTCTTCACCAAGTCCAAAGAGgt agCTGCATCCTG
spArgAspProGlyAsnProSerLeuHisSerArgPheValGluLeuSerGluAlaTyrArg
|||||||||||||||||||| |||||||||||||||||||||||| |||||||||
spArgAspProGlyAsnProAlaLeuHisSerArgPheValGluLeuAsnGluAlaTyrHis
ACCGGGACCCTGGGAACCCAGCCCTGCACAGCCGCTTTGTGGAGCTGAATGAGGCATACCAC
ValLeuSerArgGluGlnSerArgArgSerTyrAspAspGlnLeuArgSerGlySerProPr
|||||||||||||||||||||||||||||||||||| |||||||||||| ||||||||
ValLeuSerArgGluGlnSerArgArgSerTyrAspHisGlnLeuArgSerAlaSerProPr
GTGCTCAGCCGTGAGCAGAGCCGCCGTAGCTATGACCACCAGCTCCGCTCAGCCAGTCCCCC
oLysSerProArgThrThrValHisAspLysSerAlaHisGlnThrHis{Se} >>>> Ta
| ||| |||||| ||| |||||| |||||||||{||}
oArgProProGlyThrThrAlaHisProAsnSerAlaLysGlnThrHis{Se}++
AAGGCCTCCAGGAACCACAGCCCACCCCAACTCTGCCAAACAGACACAC{AG}gt
rget Intron 3 >>>> {r}SerSerTrpThrProProAsnAlaGlnTyrTrpSerGln
85 bp {|}|||||||||||| ||||||||| |||||| |||
++{r}SerSerTrpThrHisProAsnAlaHisTyrTrpAlaGln
ag{C}AGCTCCTGGACACATCCCAATGCACATTACTGGGCCCAG
PheHisSerValArgProGlnGlyProGlnLeuArgGlnGlnGlnHisLysGlnAsnLysGl
|||||| ||||||||||||||| |||||||||||||||||| |||
PheHisAspValArgProGlnGlyAlaTrpAlaArgGlnGlnGlnHisLysHisAsnGlnAr
TTTCATGATGTGAGGCCACAGGGGGCCTGGGCAAGGCAGCAGCAGCACAAGCACAACCAGCG
nValLeuGlyTyrCysLeuLeuLeuMetLeuAlaGlyMetGlyLeuHisTyrIleAlaPhe{
||||||||||||||||||||||||||||||||||||||||||||||||||| ||||||{
gValLeuGlyTyrCysLeuLeuLeuMetLeuAlaGlyMetGlyLeuHisTyrValAlaPhe{
TGTGCTGGGGTACTGCCTTCTGCTCATGCTGGCAGGCATGGGCCTGCACTACGTGGCCTTC{
Ar} >>>> Target Intron 4 >>>> {g}LysValLysGlnMetHisLeuAsnPhe
||} 669 bp {|}||| ||| ||| |||
Ar}++ ++{g}LysLeuGluGlnValHisArgSerPhe
AG}gt ag{A}AAGTTGGAGCAGGTACACCGCAGCTTC
MetAspGluLysAspArgIleIleThrAlaPheTyrAsnGluAlaArgAlaArgAlaArgSe
|||||||||||||||||||||||||||||| |||||| |||||||||||||||||
MetAspGluLysAspArgIleIleThrAlaIleTyrAsnAspThrArgAlaArgAlaArgSe
ATGGATGAAAAGGATCGGATCATCACAGCCATCTACAACGACACACGGGCACGGGCCAGGTC
rValProAlaLeuPhe-CysSerLeuLeuProValGlnGluProHisPheGlyIleProIle
|||| #||| ||| ||| |||
rValCysSerIle---#CysProLeuProProAlaProGlyThrIleLeuGlnAspProAsp
TGTCTGCTCCATC---CTGCCCCCTGCCCCCTGCTCCTGGTACCATTCTCCAAGATCCTGAC
ProThrThrGlnValProSerProProGlyProThrGluAlaSerPheSerArgSer
||| ||||||||| ||||||||||||||||||||| |||||||||
ProAspThrGlnValLeuSerProProGlyProThrGluProGlySerSerArgSer
CCAGACACCCAGGTTCTCTCTCCTCCAGGGCCAACAGAGCCAGGCTCCAGCAGGAGC
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