| Basic information |
| Official Symbol | C12orf28 |
| Description | NA |
| Other Aliases | NA |
| Other Description | NA |
| Mutation type | Insert and frame-shift 645-646:I-S^TT |
| Location | Scaffold000168_1:548929 640387 + |
| Wiki | Wikipedia GeneCard |
| Sequence |
| C12orf28 |
TTTGCAGCACAGGGGGCCAACGGCACTCTGGAGAACCCAGCCCTAGATAC AAGCCTACTGGAAGAGTTCCTGGGCAATGACTTCGATTTGGGGGCCTTGC AACGCCAGCTCCCAGATACCCCACCCTATTCTGCATCAGACCCATGCTCT CCTCCACAGATCAAAGGTGCATGCTGCCGGACCCCGAGGCCCACAGCTGG GAGGACTCTGGCCACTCTTCTCCACCCCGCAGCTGTTCCCGGGATGTTGC CTGCACACCCACCCCTGAGCACTCTGGGAAAGAGCAACTCCGGCCAAACC CAGAGCAGCTTTCACAACTGCTATCCGAACACCAGTCATCCCGCCGCCCC GCTGCACCAATCTGTGTTCTCCCATCTGGGGAGCTGTTCTAACCCCCAGC AGCCTCTGTGCCACAGCCACAGAGCCTCATTGCCTCCAACCAAGAAGAGA AAGCACGCACAGGCACTGGACGACTCCGGGGACTGCCGAGAGTGGGCCTA CCACTCCAGACCAATGACAAGTACGAGTCACAGCAGTGAAATACAGGACC ATGACAATGAGGGTCAGAACGAGATGCTTGCAGACCAATGTGCTCCTGTT CTGAAGTGGCAGCCATACCAAAGTGATCCTTGGCACAGCTTATTAAACAG TCACTATGAAAAACTTCCTGATGTGGGCTATCGCGTTGTCACAGACAAAG GATTTAATTTTTCACCAGCAGATGAAGCTTTTGTTTGCCAAAAGAAGAAT CATTTTCAGATAACCATCCACATCCAAGTTTGGGGAAGTCCAAAATTTGT TAAAACACAAATGGGCCTAAAGCCAATAGAAATGTTTTACTTGAAAGCTT TTGGAATTAAGGTAGAAGCCACCAATCAAATAATTGCTATTGAACAGTCC CAAGCAGATAGGAGCAAAAAGATATTCAATCCTGTTAAAATCAACCTGCT GACTGACCAGGTCACGAAAGTAACGCTGGGACGATTACACTTTAGTGAGA CCACAGCAAATAATATGAGAAAGAAAGGAAAACCGAATCCTGACCAGAGA TACTTCATGTTGGTGGTTGGACTATACGCTGCTAACCAGGACCAGTTCTA CTTGTTGTCTGCCCACATCTCTGAAAGGATCATTGTAAGGGCCTCTAACC CTGGGCAATTTGAAAATGACAGTGATGCATTATGGCAGCGAGGACAAGTT CCAGAATCTGTTGTCTGTCATGGTCGAGTAGGTATAAACACAAATGCACC GGACGAAGCCCTGGTTGTCTGTGGCAACGTGAAAGTGATGGGAACAGTCA TGCACCCCTCTGACAGCCGGGCAAAGCAGAATATCCAGGAGGTAGACACA AATGAACAGCTGAGAAGAATAGCCCAAATGAGGATTGTTGAATATGACTA CAAACCTGAATTTGCATCTGCAATGGGAATAAACACTGCCCATCAAACAG GAATGATTGCCCAGGAGGTGCAAGAGATCCTGCCTAGAGCTGTAAGAGAG GTTGGTGATGTCACCTGCGAAAATGGAGAAAAGTTGGAGAACTTCCTCAT GGTCGATAAGGATCAAATCTTTATGGAAAATGTAGGTGCTGTGAAGCAAC TCTGCAAACTAACCAACAATCTTGAAGAAAGAATAGAAGAGTTAGAGATA TGGAACAGAAAGCTTGCCCGGCTAAAGCGGCTTAGTAGCTGGAAGTCCTC AGTCAGTGAAGCAAGTTCAATCAGCAAATTTAGCAGAGCTGTTAGTTCAT CTTCTCCAAGAAGGGCCATTCACAAAAAATCCAACAAGGTTTATTTTTCA GGAAAAAAGCAATCGTGTCCTAACTGGGTTTTCCAGACCTTGGTTATAGC TCTAATTGCTGTGATGGCATTTTGTCCTCTCTCACTAATCATTGTCCTCC GCTCCTCCAGCAATATCACCAGCTCTCAGGAGCCAGCTCTTCCACCCACA GCCTCCCCCTCA |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 695 | 14 | 668 | Insert and frame-shift 645-646:I-S^TT |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
PheGluAlaGlnGlyAlaAsnGlyThrLeuGluAsnProAlaLeuAspThrSerLeuLeu
||| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
PheAlaAlaGlnGlyAlaAsnGlyThrLeuGluAsnProAlaLeuAspThrSerLeuLeu
TTTGCAGCACAGGGGGCCAACGGCACTCTGGAGAACCCAGCCCTAGATACAAGCCTACTG
GluGluPheLeuGlyAsnAspPheAspLeuGlyAla{Le} >>>> Target Intron
||||||||||||||||||||||||||||||||||||{||} 13677 bp
GluGluPheLeuGlyAsnAspPheAspLeuGlyAla{Le}++
GAAGAGTTCCTGGGCAATGACTTCGATTTGGGGGCC{TT}gt
1 >>>> {u}GlnArgGlnLeuProAspThrProProTyrSerAlaSerAspSerCys
{|}|||||||||||||||||||||||||||||||||||||||||| |||
++{u}GlnArgGlnLeuProAspThrProProTyrSerAlaSerAspProCys
ag{G}CAACGCCAGCTCCCAGATACCCCACCCTATTCTGCATCAGACCCATGC
SerProProGlnValLys{G} >>>> Target Intron 2 >>>> {ly}AlaCys
|||||||||||| |||{|} 96 bp {||}||||||
SerProProGlnIleLys{G}++ ++{ly}AlaCys
TCTCCTCCACAGATCAAA{G}gt ag{GT}GCATGC
TyrProThrLeuArgProThrAlaGlyArgThrProAlaProPheLeuHisProThrAla
||| ||||||||||||||||||||| ||| ||||||||| |||
CysArgThrProArgProThrAlaGlyArgThrLeuAlaThrLeuLeuHisProAlaAla
TGCCGGACCCCGAGGCCCACAGCTGGGAGGACTCTGGCCACTCTTCTCCACCCCGCAGCT
AlaProAlaMetProProMetHisProLeuGlnSerThrSerGlyMetGlyAspSerCys
||| ||| ||| |||||| |||||| ||| |||
ValProGlyMetLeuProAlaHisProProLeuSerThrLeuGlyLysSerAsnSerGly
GTTCCCGGGATGTTGCCTGCACACCCACCCCTGAGCACTCTGGGAAAGAGCAACTCCGGC
GlnIleHisGlyGlyPheHisSerCysHisSerAsnAlaSerHisLeuAlaThrProLeu
||| |||||| ||| ||| |||||| ||| ||||||
GlnThrGlnSerSerPheHisAsnCysTyrProAsnThrSerHisProAlaAlaProLeu
CAAACCCAGAGCAGCTTTCACAACTGCTATCCGAACACCAGTCATCCCGCCGCCCCGCTG
AspGlnSerValSerSerHisLeuGlyIleGlyCysSerTyrProGlnGlnProLeuCys
||||||||| |||||||||||| |||||| ||||||||||||||||||
HisGlnSerValPheSerHisLeuGly---SerCysSerAsnProGlnGlnProLeuCys
CACCAATCTGTGTTCTCCCATCTGGGG---AGCTGTTCTAACCCCCAGCAGCCTCTGTGC
HisSerPro{Gl} >>>> Target Intron 3 >>>> {y}AlaSerLeuProPro
|||||| { } 744 bp { }|||||||||||||||
HisSerHis{Ar}++ ++{g}AlaSerLeuProPro
CACAGCCAC{AG}gt ag{A}GCCTCATTGCCTCCA
ThrLysLysArgLysCysThrGlnAlaLeuGluAspSerGlyGluCysArgValTrpAla
||||||||||||||| ||||||||| ||||||||| |||||| ||||||
ThrLysLysArgLysHisAlaGlnAlaLeuAspAspSerGlyAspCysArgGluTrpAla
ACCAAGAAGAGAAAGCACGCACAGGCACTGGACGACTCCGGGGACTGCCGAGAGTGGGCC
CysHisCysArgPro{M} >>>> Target Intron 4 >>>> {et}ThrSerArg
||| ||||||{|} 15415 bp {||}||||||
TyrHisSerArgPro{M}++ ++{et}ThrSerThr
TACCACTCCAGACCA{A}gt ag{TG}ACAAGTACG
SerArgSerSerGluValGlnAspProAspSerGluGlyGlnAsnArgMetProThrAsp
||| ||||||||| |||||| ||| |||||||||||| ||| |||
SerHisSerSerGluIleGlnAspHisAspAsnGluGlyGlnAsnGluMetLeuAlaAsp
AGTCACAGCAGTGAAATACAGGACCATGACAATGAGGGTCAGAACGAGATGCTTGCAGAC
GlnCysSerProAlaLeuLysTrpGlnProCysHisSerValProTrpHisSerLeuLeu
|||||| ||| ||||||||||||||| ||| ||||||||||||||||||
GlnCysAlaProValLeuLysTrpGlnProTyrGlnSerAspProTrpHisSerLeuLeu
CAATGTGCTCCTGTTCTGAAGTGGCAGCCATACCAAAGTGATCCTTGGCACAGCTTATTA
AsnSerHisTyrGluLys{Le} >>>> Target Intron 5 >>>> {u}ProAsp
||||||||||||||||||{||} 7093 bp {|}||||||
AsnSerHisTyrGluLys{Le}++ ++{u}ProAsp
AACAGTCACTATGAAAAA{CT}gt ag{T}CCTGAT
ValGlyTyrArgValValThrAspLysGlyPheAsnPheSerProAlaAspGluAlaPhe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValGlyTyrArgValValThrAspLysGlyPheAsnPheSerProAlaAspGluAlaPhe
GTGGGCTATCGCGTTGTCACAGACAAAGGATTTAATTTTTCACCAGCAGATGAAGCTTTT
ValCysGlnLysLysAsnHisPheGlnIleThrIleHisIleGlnValTrpGlySerPro
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ValCysGlnLysLysAsnHisPheGlnIleThrIleHisIleGlnValTrpGlySerPro
GTTTGCCAAAAGAAGAATCATTTTCAGATAACCATCCACATCCAAGTTTGGGGAAGTCCA
LysPheValGluThrGluMetGlyLeuLysProIleGluMetPheTyrLeuLysValPhe
||||||||| ||| |||||||||||||||||||||||||||||||||||| |||
LysPheValLysThrGlnMetGlyLeuLysProIleGluMetPheTyrLeuLysAlaPhe
AAATTTGTTAAAACACAAATGGGCCTAAAGCCAATAGAAATGTTTTACTTGAAAGCTTTT
GlyThrLys >>>> Target Intron 6 >>>> ValGluAlaThrAsnGlnIleI
||| ||| 1854 bp ||||||||||||||||||||||
GlyIleLys++ ++ValGluAlaThrAsnGlnIleI
GGAATTAAGgt agGTAGAAGCCACCAATCAAATAA
leAlaIleGluGlnSerGlnAlaAspArgSerLysLysIlePheAsnProVal{Ly} >
|||||||||||||||||||||||||||||||||||||||||||||||||||||{||}
leAlaIleGluGlnSerGlnAlaAspArgSerLysLysIlePheAsnProVal{Ly}++
TTGCTATTGAACAGTCCCAAGCAGATAGGAGCAAAAAGATATTCAATCCTGTT{AA}gt
>>> Target Intron 7 >>>> {s}IleAspLeuLeuAlaAspGlnValThrLysV
1175 bp {|}||| |||||| ||||||||||||||||
++{s}IleAsnLeuLeuThrAspGlnValThrLysV
ag{A}ATCAACCTGCTGACTGACCAGGTCACGAAAG
alThrLeuGlyArgLeuHisPheSerGluThrThrAlaAsnAsnMetArgLysLysGlyL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
alThrLeuGlyArgLeuHisPheSerGluThrThrAlaAsnAsnMetArgLysLysGlyL
TAACGCTGGGACGATTACACTTTAGTGAGACCACAGCAAATAATATGAGAAAGAAAGGAA
ysProAsnProAspGln{Ar} >>>> Target Intron 8 >>>> {g}TyrPheM
|||||||||||||||||{||} 3299 bp {|}|||||||
ysProAsnProAspGln{Ar}++ ++{g}TyrPheM
AACCGAATCCTGACCAG{AG}gt ag{A}TACTTCA
etLeuValValGlyLeuTyrAlaAlaAsnGlnAspGlnPheTyrLeuLeuSerAlaHisI
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
etLeuValValGlyLeuTyrAlaAlaAsnGlnAspGlnPheTyrLeuLeuSerAlaHisI
TGTTGGTGGTTGGACTATACGCTGCTAACCAGGACCAGTTCTACTTGTTGTCTGCCCACA
leSerGluArgIleIleValArg >>>> Target Intron 9 >>>> AlaSerAs
||||||||||||||||||||||| 10987 bp ||||||||
leSerGluArgIleIleValArg++ ++AlaSerAs
TCTCTGAAAGGATCATTGTAAGGgt agGCCTCTAA
nProGlyGlnPheGluAsnAspSerAspAlaLeuTrpGlnArgGlyGlnValProGluSe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nProGlyGlnPheGluAsnAspSerAspAlaLeuTrpGlnArgGlyGlnValProGluSe
CCCTGGGCAATTTGAAAATGACAGTGATGCATTATGGCAGCGAGGACAAGTTCCAGAATC
rIleValCysHisGlyArgValGlyIleAsnThrAspAlaProAspGluAlaLeuValVa
| |||||||||||||||||||||||||||||| |||||||||||||||||||||||
rValValCysHisGlyArgValGlyIleAsnThrAsnAlaProAspGluAlaLeuValVa
TGTTGTCTGTCATGGTCGAGTAGGTATAAACACAAATGCACCGGACGAAGCCCTGGTTGT
lCysGlyAsnMetLysValMetGlyThrIleMetHisProSerAspSerArgAlaLysGl
|||||||||| ||||||||||||||| |||||||||||||||||||||||||||||
lCysGlyAsnValLysValMetGlyThrValMetHisProSerAspSerArgAlaLysGl
CTGTGGCAACGTGAAAGTGATGGGAACAGTCATGCACCCCTCTGACAGCCGGGCAAAGCA
nAsnIleGlnGlu >>>> Target Intron 10 >>>> ValAspThrAsnGluGl
||||||||||||| 8141 bp |||||||||||||||||
nAsnIleGlnGlu++ ++ValAspThrAsnGluGl
GAATATCCAGGAGgt agGTAGACACAAATGAACA
nLeuLysArgIleAlaGlnMetArgIleValGluTyrAspTyrLysProGluPheAlaSe
|||| |||||||||||||||||||||||||||||||||||||||||||||||||||||
nLeuArgArgIleAlaGlnMetArgIleValGluTyrAspTyrLysProGluPheAlaSe
GCTGAGAAGAATAGCCCAAATGAGGATTGTTGAATATGACTACAAACCTGAATTTGCATC
rAlaMetGlyIleAsnThrAlaHisGlnThr{G} >>>> Target Intron 11 >>
|||||||||||||||||||||||||||||||{|} 809 bp
rAlaMetGlyIleAsnThrAlaHisGlnThr{G}++
TGCAATGGGAATAAACACTGCCCATCAAACA{G}gt
>> {ly}MetIleAlaGlnGluValGlnGluIleLeuProArgAlaValArgGluValG
{||}||||||||||||||||||||||||||||||||||||||||||||||||||||
++{ly}MetIleAlaGlnGluValGlnGluIleLeuProArgAlaValArgGluValG
ag{GA}ATGATTGCCCAGGAGGTGCAAGAGATCCTGCCTAGAGCTGTAAGAGAGGTTG
lyAspValThrCysGlyAsnGlyGluThrLeuGluAsnPheLeuMetValAspLys >>
|||||||||||||| ||||||||| |||||||||||||||||||||||||||
lyAspValThrCysGluAsnGlyGluLysLeuGluAsnPheLeuMetValAspLys++
GTGATGTCACCTGCGAAAATGGAGAAAAGTTGGAGAACTTCCTCATGGTCGATAAGgt
>> Target Intron 12 >>>> AspGlnIlePheMetGluAsnValGlyAlaValL
17125 bp ||||||||||||||||||||||||||||||||||
++AspGlnIlePheMetGluAsnValGlyAlaValL
agGATCAAATCTTTATGGAAAATGTAGGTGCTGTGA
ysGlnLeuCysLysLeuThrAsnAsnLeuGluGluArgIleGluGluLeuGluIleTrpA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ysGlnLeuCysLysLeuThrAsnAsnLeuGluGluArgIleGluGluLeuGluIleTrpA
AGCAACTCTGCAAACTAACCAACAATCTTGAAGAAAGAATAGAAGAGTTAGAGATATGGA
snArgLysLeuAlaArgLeuLysArgLeuSerSerTrpLysSerSerAlaSerGluAlaS
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||
snArgLysLeuAlaArgLeuLysArgLeuSerSerTrpLysSerSerValSerGluAlaS
ACAGAAAGCTTGCCCGGCTAAAGCGGCTTAGTAGCTGGAAGTCCTCAGTCAGTGAAGCAA
erThrIle{Se} >>>> Target Intron 13 >>>> {r}LysSerSerArgAla
|| |||{||} 856 bp {|}||| |||||||||
erSerIle{Se}++ ++{r}LysPheSerArgAla
GTTCAATC{AG}gt ag{C}AAATTTAGCAGAGCT
ValSerAlaSerSerProArgArgAlaValHisLysLysAsnAsnLys >>>> Targe
|||||| |||||||||||||||||| ||||||||| ||||||
ValSerSerSerSerProArgArgAlaIleHisLysLysSerAsnLys++
GTTAGTTCATCTTCTCCAAGAAGGGCCATTCACAAAAAATCCAACAAGgt
t Intron 14 >>>> ValTyrPheSerGlyLysArgGlnAlaCysProAsnTrpVal
5278 bp |||||||||||||||||| ||| |||||||||||||||
++ValTyrPheSerGlyLysLysGlnSerCysProAsnTrpVal
agGTTTATTTTTCAGGAAAAAAGCAATCGTGTCCTAACTGGGTT
PheGlnThrLeuValIleThrLeuIleAlaValMetAlaPhe{Cy} >>>> Target
|||||||||||||||||| |||||||||||||||||||||{||} 29
PheGlnThrLeuValIleAlaLeuIleAlaValMetAlaPhe{Cy}++
TTCCAGACCTTGGTTATAGCTCTAATTGCTGTGATGGCATTT{TG}gt
Intron 15 >>>> {s}ProLeuSerLeuIleIle--SerPhePhePheSerSerAsn
46 bp {|}||||||||||||||||||## |||||||||
++{s}ProLeuSerLeuIleIle##ValLeuArgSerSerSerAsn
ag{T}CCTCTCTCACTAATCATTTTGTCCTCCGCTCCTCCAGCAAT
IleThrSerSerGlnGluProAlaLeuLeuProThrAlaSerSerSer
||||||||||||||||||||||||||| |||||||||||| |||
IleThrSerSerGlnGluProAlaLeuProProThrAlaSerProSer
ATCACCAGCTCTCAGGAGCCAGCTCTTCCACCCACAGCCTCCCCCTCA
//
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