| Basic information |
| Official Symbol | ASPM |
| Description | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| Other Aliases | RP11-32D17.1, ASP, Calmbp1, MCPH5 |
| Other Description | abnormal spindle-like microcephaly-associated protein |
| Mutation type | premature termination 3080:K->TAA |
| Location | Scaffold000453_1:163191 115226 - |
| Wiki | Wikipedia GeneCard |
| Sequence |
| ASPM |
NNGGCTTCCCCGCCCCTCCTGTCGCTCAGCCACTTCTGCAGATCTCCTTT TGTTTGCTTCGGGGACGTGCGCCTGGGGACCTCGCGGACGCTGCCTCTGG CGGTGCAGAACCCGAACCAAGAGGTGGCCGAAGTGCGGATTTCTCAGTTC CCGGCCGCAGACCTGGGCTTCACCGTGTCGCCGCGCAGTTTCGTGTTGCA GCCTGAAGAAAAAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAG GCCGAGTAAGAGCCACTGTGACATTTCTTGTAAATGATGTTCTGAAACAC CAAGCCATATTACTAGGAAATGCAGAAGAGCAGAAAAAGAAACAGAGGAG TCTTTGGGATACCACTAATAAGAAAAAAAGTTCAGCTTCTTCAAGTCATA ACAAAAGGATTTCAAATTCTCAAAATATTAATAAGACATTCAGTGTTGCT CAAAATGTTGATAGAGTTAGGAGCCCACTGCAAGCTTGTGAAAATCTGGC AATGAATGAAGGCTGTTCCCCAACAGAAAACAATTTTTTAACACTTGAAG AAAATAAAATTCTTATATCACCCATTAGCCCTGCTTTGAAAGAATGCCAC AGTGAAATTTGCTTACCGCTCTCTGTACGTCGATCTACCACCTACTCATC TCTTCATGCCTCCGAAAATGGAGAGACGTTGAAAACAGAAAATGGCAACG TCGCAAAAGATTTTAATTGTAATGAGGAAGTCATAACTGAACGTTCCTTT AATTCCATAAATACTAATGACCAAAGTGGAGAGAATAAACTGACTCTTAC CCCAAACTACTCAACTTTGAATATTACACAAAGCCACACACATTTCCTAA GTCCAGATTCTTTTGTAAATAATAGCCGTACAGCTAATAATGGGCTAGAA TTAGTGACATGTCTTACATCAGAGACATTTATGAGAGATAATTCAAAGCC TGTATATTTGGAATCTAACACTGTACGTGAAACTTATCGGACAATTTTAA GTCCAAATTCTTTTATAAATGATAGTTATGGAATAAATCAACCTCTAGAA TCAGAGTCAGTAAATCCCATTTTATCCCCACATCAATTTGTCAAAGACAA TATGACATATATATGTACATCTCAGCCAACATGTAAATTGCTATCATCAC CAAATGAAAATTCTCAGATCCCAGAGCTTCAGAACTGGAGAAAAAGTGAA GTTTTGCCATGCATTTCTAAATGTCAGGGTTCAAAGTCTCCCCAAGCTAT TTTCAAAGAACTCAAAGCTGTAGAAACAAAGTCGAATAGCAACAGTTTCA CAGCACAAAATCATTCTAAATTTTCTGCAGTTCAGGATATTTCTAGTCAC AGCCACAAAAAACAACCTAAGAGACGCCCAATACTTTCTGCCACTGTTAC TAAAAGGAAGCTTATCCATGCCAGAGAAAACAAAACTGAGATGAATAAAC CGAAAGCAAAAAAATGTCTCAACAACGCAGTAGGTGAATGTGAAAAAGTA ACAGATACTCCAAAAGAGAAAGAAGCTTTTCTTTCTTATCTTCCAATTAT AGAGCCAATATTAAGTAAATCTAAGAGTTATAAAGAAGCAGTGACTCCTT CAATGGTTACTCGTAAAAGAAAGAGTGATGAAAACCTGGAAGCTGCAAAT GTGAGGGTTGTGGTTACAGAACACATAGGGGTGCAAGAAATCAAAAGAAT TCATTTTTCTCCCTCTGAACCCAAAACATCAACTGTAAAAAAAACAAAAA AGGTGATAACACCCATCTCAAAAAGCAACAGAGAGAAATTAAGCCTGAAG AAGAAAACTGATTCATTCATATTCAAAACTCCTACTTCTAAACCAAACAA AAGGACAAAGCCCGTTATTGCTGTGGCACAGTCCAGTCTGACCTTCATAA AACCATTAAAAACAGATATTCCTAGACATCCAATGCCTTTTGCTGCAAAA AACATGTTTTACGATGAACGTTGGAAGGAAAAACAGGAACAGGGCTTCAC TTGGTGGCTAAATTTTATATTAACTCCTGATGACTTCACTGTAAAAACAA ATATTTCTGAAGTAAATGCTGCTACTCTCTTTTTGGGAGTAGAGAATCAA CATAAAACCAGTGTTCCTAGGGCACCTACGAAAGATGAAGTGTCTCTCCG AGCTTATACTGCGCGGTGCAGGATGAACAGGTTACGCCGTGCAGCTTGCC GTTTATTTACTTCTGAAAAAATGGTCAAGGCTATTAAAAAGCTTGAAATT GAAATTGAAGCTAGGCGGTTAATCGTTCGAAAAGATAGACACCTCTGGAA AGATATAGGAGAACGCCAGAAAGTCTTGAATTGGTTGTTGTCATATAATC CTCTGTGGCTTCGAATTGGCCTAGAGACAGTTTATGGAGAACTCATAGCT TTGGAAGGCAACAGCGATGTCACAGGGCTGGCTATGTTTATTCTGAATCG CTTGCTTTGGAATCCTGATATAGCAGCTGAGTATAGACACCCTTCTGTTC CTCATCTTTACAGAGATGGCCATGAAGAAGCTTTGTCCAAGTTTACACTG AAAAAGTTATTGTTGTTGGTCTGTTTCCTTGACTATGCTAAAATTTCCAG ACTTATTGATCATGATCCTTGTCTCTTCTGTAAAGATGCCAAATTCAAGG CAAGTAAGGAAATTCTTCTGGCTTTTTCACGTGATTTCCTAAGTGGTGAA GGTGACCTTTCTCGTCACCTTAGCTTCCTGGGATTACCTGTTAACCATGT TCAGACACCATTTGATGAATTTGATTTTTCTGTTACAAATCTTGCTGTAG ACTTGCAGTGCGGCGTGCGTCTTGTGAGAACCATGGAACTTCTCACACAG AATTGGGATCTCTCAAAGAAACTCAGGCTTCCTGCAATAAGTCGTCTTCA AAAGATGCACAACGTGGACATTGTTCTTCAAGTTCTTAAGTCACGAGGAA TTCAATTAAATGATGAGCATGGAAATACAATTCTATCTAAGGACATAGTA GACAGACACAGAGAAAAAACTCTTGGGCTGCTTTGGAAAATAGCATTTGC TTTTCAGGTGGATATTTCCCTTAATTTAGACCAATTAAAGGAAGAAATTG ACTTTTTAAAATGTGCACGGAGTATAAAGAAAACAATGTCTGCACTATCT TGCCGATCTGATGCTGTTATTAATAAGAAAAAAGAAAAAATGAATAGTGG TCCTTTTGAGCAATATAGTGAAAAAATAAACTTATTGATGGATTGGGTAA ATGCTGTTTGTGCCTTCTACAATAAACAAGTGGAGAACTTCACAGTGTCA TTCTCTGACGGCCGGGTGTTGTGTTACCTGATCCACCACTACCATCCTTG CTATGTGCCTTTTGACGCTATATGCCAGCGCACTACTCAGACTGTGGAGT GCACCCAGACCGGTTCCGTGGTGTTAAATTCATCGTCTGAATCCGATGAT AGTTCTCTGGATATGTCTCTTAAAGCATCTGAAAATGAAAATAATTCAGG ATTATACAAAGAACTCTTAGAAAATGAAAAGAAAAATTTTCATTTGATTA GCTCTGCAGTAAGAGACCTTGGTGGAGTACCTGCTATGATTCATCATTCA GACATGTCAAATACAATTCCAGATGAAAAGGTTGTTATTACCTATTTGTC GTTTCTTTGTGCAAGGCTTTTGGATCTTCGCAAAGAAATAAGAGCTGCTC GACTTATACAAACCATGTGGAGAAAATATAAACTAAAAACGTACCTAAAA TACCACCAGGAAAGAGACAAAGCTGCAAGAATTATTCAATCAGCTGTAAT CAATTTTCTAACCAAACGACGACTGAAAAAAGAGGTTCATGCAGTGCTGG TCATTCAGAAACACTGGCGAAGAATCTTAGCACAGAGAAAATTAAAGGAA AAACTGGAAAAAGTGCAAAATAAATCAGCATCTGTTATTCAGAGATATTG GAGAAGATACTCCACTAGAAAAAGATTTCTCAAGTTGAAACATTACTCAA TCATCCTGCAATCTAGAATAAGAATGATAATTGCTGTCACATCTTATAAA CGATATCTGTGGGCAACAGTTACAATTCAGAGATATTGGCGGGCTTATTT AAGAAGAAAACAAGATCAACAAAGATATGAAATGCTAAGATCAGCTACCC TTGTAATCCAGGCTAGGTTCAGAAGATGGAAGCGATGTAAGATGCTATTA CAAATAAAAGCTACAAGAATATTACAAAGAGCTTTCAGAGAATGGCATTT CAGGAAACGCGCTAAAGAAGAAAAGTCTGCTGTTATCATACAGTCATGGT ATAGAATGCACAAAGAACTGAGGAAATATATGTATATTAGATCTTGTATT GTTACCATTCAGAGAAGATTTCGGTGTTTTCAAGCCCAAAAATTATATAA AAGAAAAAAAGAGTGTATACTGACTATTCAGAAGTACTTCAGAGCATATC TGAATGGGAAGACGGAGCGCACCAAGTATTTGCAGAAACGAGCTGCAGCC CTTCAGCTTCAGGCTGCTTATAGGAGAATGCAAGCTCGTAACTTACACAG ACGAGCTAGAGCTGCTCATGTTCTTCAGTCATATTGGAGGATGAGACAAG TCAGACTGCAATTTTTAAACCTCAAGAAGGTTGTTATCAAAATGCAGGCA CATATAAGAAAACATCAACAATTACAGAAATATAAGAAGATGAAGGAAGC AGCACTTGTAATTCAGACCCATTTCCGAGCTTACCTTTCAGCCAGGAGAG TTCTGGCATCTTATCAGAAAACTCGTTCTGCTGTCATTGTTTTACAGTCT GCATATAGAAGAATGAAAGCCAGGAAAACATTTATTCGGATTCTCACATC TGTTGTAAAGATTCAATCATATTATCGTGCTTATATTTCCAGAAAGAAAT TTCTGAGCCTGAAAAATGCTACAATAAAATTGCAATCAATTGTCAAGATG AAGCAAACACGTAAACAATATTTACATTTAAGAACAGCTGCAGTGTTTAT CCAGCAATGGTACCGTTCCCAAAAAATAGCTACACAAAAGAGAGAAGAAT ATACACAGATGCGGGAATCTTGTATCAAGCTGCAAGCTTTGGTTAGAGGC TTCCTGGTCCGAAAGCAGATGAGTTTGCAAAGAAAAGCTGCTGTTTCACT CCAGTCTTATTTCAGAATGAGAAAGATGCGGCAGCACTACTTGAAAATTT ATAAGGCAACTGCTGTCATCCAGAAACACTATCATGCATACAAAGCACGA GTCTACGAGAGGAAGAACTTCTTGCAAGTCAAAAGAGCAGCGACTTGTCT GCAAGCAGCTTACAGAGGCTATAAAGTGCGCCAACTCATAAAACGACAAT CTGTAGCCGCACTTAAAATTCAAGCTGTCTTTAGGGGGCATAGTAAAAGG GTGAAATATCAGTCTGTGCTGCAGTCTGCTGTGAAGATTCAGAGATGGTA CAGGGCATACAAGACTGTTTATAATGTAAGAACACATTTTTTGAAGATGA GAGCAGCTGTGATTTCTCTCCAGTCAGCCTACCGTGGCTGGAAAGTTCGG AAACAGATCAGAAGGGAACAGCAAGCTGCAATGAAGATTCAGTCTTGTTT TAGGATGGTCAGGGCCCAGAAACAGTTCAGATTGTTAAAAACAGCAGTAA TAGTCATCCAACAACATCTGAGAGCATGGACCGCAGGAAAGAAACAACGT ATGGAGTATCTTGAACTCCGTCGTGCAGTCCTGATACTTCAGTCTGCCTG GAAGGGAAGGACACTGAGAAGACAGATTCAAAGGCAACACAAGTGTGCTG TCATCATTCAGTCATACTATAGGATGTACGTGCAACAACAGAAGTGGAAA TCCATGAAAAAAGCTGCTCTTCTGATTCAAATGTATTATAGGGCTTACAG TACTGGAAGAAAACAGCATCGATTATATCTGAAAACAAAAGCAGCTGCAG TAGTTTTACAGTCCACATATCGGGGTAAGAAAGTGAGAAAAAGAATAAAG GATTGCAACAAAGCAGCAGTCACTATTCAGTGTACATATAGAGCTTATAA AGCCAGAAAGAAATATGCAATGTATAGAGCTTCAGCTATTACAATTCAGA GATGGTATAGAGGTATTACAATTGCAAGCCATCTACATGAGGAATATCTT ACTTTAAAGAAGACTGCAGTTAAAATCCAAGCCGTTTATAGAGGGATTAG AGTAAGAAGACATATTAAACACATGCACATGGCAGCCACTTTTATTAAAG CCACATTTAAAATGCATCAGTCAAGAGTGAAATACCATAAAATGAGAACA GCGGCTATTGTCATTCAAGTAAGATATAGAGCATATTATCAAGGTAGAGT TCAGCGTGAAAAGTATCTGACAATTTTGAAAGCCATCCATGTTCTTCAGG CAAGTTTTAGAGGAGCGAGAGTTAGACAGAGTCTAAGAAAGATGCAGATT GCAGCCACACTCATTCAGTCATACTATAGAAGACACAAACAACAAGCATA TTTTAATAAGTTAAAAAGGGTAACAGAAACAGTACAACAAAGATATCGGG CACTGAAGGAAAGAAACATGCAGTTTCAAAGGTATAACAAATTGAGGCAT TCTGTGATACGCATTCAGGCTGGTTTCAGGGGCTGGAAAGTTAGACGACA TTTGAAGATTATGCATCTAGCTGCAACCCTTATTCAGAGAAGATTTAGAA TGCTAATGATGAGAAGAAGATTCCTATCGCTCAGGAAAACTGTTGTTTGG ATTCAGAGAAAATATCGTGCAAATCTTCATGCCAGACATCACTTACGACA GTTCCTTTGGTTACGAAAGGCAATTATTAAAATCCAGTCATTATACAGAG GATGGACAGTAAGGAAGAAGATGCGAGAGATGCACATGGCTGCTGCTTGT ATCCAGGCTACTTTCAAAATGCACAGAGCACGTGTGAGACACCAGGCTTT GAAACAGGCCTCAGTCGTGATCCAACAGAGATACCGAGCAACCAGAGCCG CGAAACTGCAGAGGCAGCATTACCTCCAACAAAGACATTCAGCCGTGATC CTGCAGGCTGCATTTAGGGGCATGAAAGCTAGAAGACATCAGAAAAGGAT GCATTCCTCTGCGACCCTTATTCAGAGTAGGTTTAGATCATTAGTGGTGA GGAGAAGATTCCTCTCACTCAAGGAAGCTGCTATTTCTGTTCAGAGGAAA TACCGAGCCACCATTTGTGCCAAGCATCAGTTGCACCAGTTCCTGCAGTT ACGAAAGGCAGCCATTGTGATTCAGTCATCGTACCGAAGACTGATAGTAA AGAGGAAGTTACAAGAAATGCAAAGGGCCGCGGTTCTCATTCAGGCTACT TTCCGAATGCACAGAACATACGTGGCATTTCAGACTTGGAAACAGGCCTC AGTTCTAATTCAGCGACATTATCGGACATATAGAGCTGCAAAATTGCAAA GAGAAAATTATATTAGACGATGGCGTTCTGCCATTGTCATTCAGTCTGCA TACAAAGGAATGAAAGCAAGACAGCTTTTGAGGGAAAGACACAGAGCTGC TGTCATAATACAAAGCACTTATAGAATGTATAGGCACTACTATTTCTACC AAAGGCTTCAGTGGGCTGCAAAAGTAATACAAGAAAAATATAGAGAAAAT AAAAAGAAACAGACAGCTCTTCAACCCGGTGAACTTAAGAAAGCAGCAAC TTTTACTCAGGCAGGTTTTCAGGACATGAACATCAGCAAACACATTCAGA AACAACATCAGGCTGCCATTATTGTTCAGAAGCACTTCAAAACCTTTCAA ATGAGGAGGCATTATCTCCACCTTAGAGCAACAGTAGTTTCTATTCAAAG AAGATACAGAGCACGCGCAGCAATGCGTAACCAAGCAGCTACTTGTATAC AGGCTTCTTACAGAGGCTTTAAGGCACGAAGGCATATACAGCAGATGCAC CTGGCTGCCACACTAATTCAGTCACTCTACCGAATGCACAGGGCCCAAGG TGACTATCGAGCAAAGAAAACTGCAATTGCTATTATACAGAATTATTATA GGTCATATGCCAGTGTGAAAAGGGAACGAAAACAATTTTTAGTGGTTCAG AAATCTGTACGAACCATTCAGGCTGCTTTTAGAGGCATGAAAGTTCGACA GAAATTGAAAACCATATCTGAGGGAAAGACAACAGCCATTGCTAACCAAT CTGCATTCTCCTGTCTCGGAACTGAAACCCAATATGAAACTGTTCAAAGT GGGGGTGTTATGATTCGAAATAGAACTTCACTTGCCAGTTCACAGGAAGC AGAGTATCATTCTCAAAGTACAGCTGCAGTCACAAGGCAAAAAGCTTTTC AGAAAATGGTCACAAGAAAACTGGAAACTCAGAAATGTGCTGCCGTACAA ATTCAGTCCTTTCTTCAGATGGCCATGTGTCGACGAAGGTTCATCCAGCA GAGAAGAGCTGCTGTCACTTTACAGCGTTACTTCAGGACATGGCAAACCA GAAAACAATTTTTACTGTATAGAAAAGCAGTGGTGGTTTTACAACATCAC CACCGAGCCTTTCTGTCTGCCCGACAGCAAAGACAGGTGTATTTACAAAT CAGACGCAACGTTATCATGATTCAAGCTAGAACGAGAGGATTTATACAGA AACGGAAATTTCAGAAAATTAAAAGTAGCACCATAAAAATTCAGGCTGTA TGGAGGAGATATAAAGCCAAAACGTATTTATCTAAAGTGAAAGCTGCCTG CAAAATTCAAGCCTGGTATAGATGTTGGAGAGCACGCAAAGAATATCTAG CTGTATTACAAGCTGTGAGATTTATTCAGGGTTGCATCCGTACCAAATTG GAGAGAGCACGGTTTTTGAATATGAGAGCATCAGCAATTGTCATTCAGAG AAAGTGGAGAGCTACACTTGCTGCAAGACAAGCTCGTGAGCACTTCATAA TGACAAAAAGCCATCGAGCTGCTTGTTTGATCCAAGCACATTTTAGAGGC TATAAAGGAAGGCAGGTCTTCCTTCAGCAGAAATCTGCTGCTTTGATCAT ACACAGATATATACGAGCCAGGGAGGCTGGGAAATATGAAAGGATAAAAT ATGTTGAATTTTAAATATCCACAGTTGTTCTACAAGCACTGGGTTGGTTA GTAAGAAAAAGAATTTTGGAACAGAGAGCCAAAATTCGGCGTCTTCACTT CACAGCAGCTGCCTATTATCACCTGTCTGCTATTAGAATTCAAAGAGCAT ATAAACTTTACATGGCAGTGAAGAATGCTAAAAAGCAGCTTAATTCAGTC ATCTGTATCCAGAGATGGTTTCGAGCAAGAATACAACACAAGAAGATGAT TCAGAAGTCTCATAACGTCATAGAAGTGGAGCATGAAGTTCAAGAACATC TGAACCAGCAACACAGAGCAGCATCAGTAATACAGAAAGCAGTGCGCCAA TTTCTTCTTCACAAAAAACAGGAAAAATTTAATAGTGGAATAACTAAAAT TCAGGCATTGTGGAGAGGCTACTCTTGGAGGAAGAAACATGACTGTACAA AAATTAAAGCTATACGACTAAGTCTTCAACTTGTTAATAGGGAGATTCAA GAAGAAGACAAGCTCTACAAAAGAACCGCACTCGCACTTCATTCCCTGTT GACGTACAAGCACCTTTCTGCCATTCTGGAAGCTTTAAAACACCTAGAGG TGGTAACTAGATTGTCTCCTCTTTGTTGTGAGAACATGGCCCAGAGTGGA GCGATTTCTAAAATATTTGTTTTGATCCGAAGTTGTAATCGTAGTGTTCC TTGTATGGAAGTCATCAGATATGCTGTTCAAGTCTTGCTTAATGTAGCTA AGTACGAGAAAACCACTTCAGCAGTTTATGATGCAGAAAATTGCATAGAT ACACTATTGGAGCTTCTGCAGATATATCGAGAAAAGCCTGGTGACAAAGT CGCAGACAAGGGTGGAAGCATTTTTACAAAAACTTGTTGTTTGTTTGCTG TTTTATTGACAACAACGAATCGAGCCTCTGATGTACGAAGCAGGTCCAAA GTTATTGACCGTATTTATAGTCTCTATAAGCTTACAGCACGTAAACATAA AATTAATACTGAAAGAATAACTTATAAACAAAAGAAGAATCCTTCTCTAA GTATTCCCTTTATTCCAGAAACACCTGTAAGGACCAGAATAGTTTCAAGA CTTAAACCTGATTGGATTTTGAAAAGAGATAAGCTAGAAGAAATAACGAA TCCCCTTCAAGCTATTCAGATGGTGATGGATACCCTTGGCATTCCCTAT |
| Alignment |
| Align specie | Pep length | Pep align begin | Pep align end | Mutaion type and postion |
| Human | 3477 | 33 | 3477 | Premature termination 3080:K->TAA |
Instructions:
*** -> premature termination codon; # -> frame shift
Alignment:
Human pep sequence --->
||||||||||||||||||||||
Treeshrew pep sequence --->
Treeshrew cds sequence --->
AlaSerSerProProValLeuSerLeuSerHisPheCysArgSerProPheLeuCysPhe
||||||||| ||||||||||||||||||||||||||||||||| ||||||
UnkAlaSerProProLeuLeuSerLeuSerHisPheCysArgSerProPheValCysPhe
NNGGCTTCCCCGCCCCTCCTGTCGCTCAGCCACTTCTGCAGATCTCCTTTTGTTTGCTTC
GlyAspValLeuLeuGlyAlaSerArgThrLeuSerLeuAlaLeuAspAsnProAsnGlu
||||||||| |||||| |||||||||||| |||||| |||||||||
GlyAspValArgLeuGlyThrSerArgThrLeuProLeuAlaValGlnAsnProAsnGln
GGGGACGTGCGCCTGGGGACCTCGCGGACGCTGCCTCTGGCGGTGCAGAACCCGAACCAA
GluValAlaGluValLysIleSerHisPheProAlaAlaAspLeuGlyPheSerValSer
||||||||||||||| |||||| |||||||||||||||||||||||| ||||||
GluValAlaGluValArgIleSerGlnPheProAlaAlaAspLeuGlyPheThrValSer
GAGGTGGCCGAAGTGCGGATTTCTCAGTTCCCGGCCGCAGACCTGGGCTTCACCGTGTCG
GlnArgCysPheValLeuGln >>>> Target Intron 1 >>>> ProLysGluL
||| |||||||||||| 3561 bp ||| ||||
ProArgSerPheValLeuGln++ ++ProGluGluL
CCGCGCAGTTTCGTGTTGCAGgt agCCTGAAGAAA
ysIleValIleSerValAsnTrpThrProLeuLysGluGlyArgValArgGluIleMetT
|||||||||||||||||||||||||||||||||||||||||||||||||| |
ysIleValIleSerValAsnTrpThrProLeuLysGluGlyArgValArgAlaThrValT
AAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAGGCCGAGTAAGAGCCACTGTGA
hrPheLeuValAsnAspValLeuLysHisGlnAlaIleLeuLeuGlyAsnAlaGluGluG
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
hrPheLeuValAsnAspValLeuLysHisGlnAlaIleLeuLeuGlyAsnAlaGluGluG
CATTTCTTGTAAATGATGTTCTGAAACACCAAGCCATATTACTAGGAAATGCAGAAGAGC
lnLysLysLysLys >>>> Target Intron 2 >>>> ArgSerLeuTrpAspTh
||||||||||| 159 bp |||||||||||||||||
lnLysLysLysGln-- ++ArgSerLeuTrpAspTh
AGAAAAAGAAACAGaa agAGGAGTCTTTGGGATAC
rIleLysLysLysLysIleSerAlaSerThrSerHisAsnArgArgValSerAsnIleGl
| ||||||||| ||||||||| ||||||||| ||| |||||| ||
rThrAsnLysLysLysSerSerAlaSerSerSerHisAsnLysArgIleSerAsnSerGl
CACTAATAAGAAAAAAAGTTCAGCTTCTTCAAGTCATAACAAAAGGATTTCAAATTCTCA
nAsnValAsnLysThrPheSerValSerGlnLysValAspArgValArgSerProLeuGl
|||| |||||||||||||||||| ||| ||||||||||||||||||||||||||
nAsnIleAsnLysThrPheSerValAlaGlnAsnValAspArgValArgSerProLeuGl
AAATATTAATAAGACATTCAGTGTTGCTCAAAATGTTGATAGAGTTAGGAGCCCACTGCA
nAlaCysGluAsnLeuAlaMetAsnGluGlyGlyProProThrGluAsnAsnSerLeuIl
||||||||||||||||||||||||||||||| ||||||||||||||| |||
nAlaCysGluAsnLeuAlaMetAsnGluGlyCysSerProThrGluAsnAsnPheLeuTh
AGCTTGTGAAAATCTGGCAATGAATGAAGGCTGTTCCCCAACAGAAAACAATTTTTTAAC
eLeuGluGluAsnLysIleProIleSerProIleSerProAlaPheAsnGluCysHisGl
|||||||||||||||||| ||||||||||||||||||||| |||||||||
rLeuGluGluAsnLysIleLeuIleSerProIleSerProAlaLeuLysGluCysHisSe
ACTTGAAGAAAATAAAATTCTTATATCACCCATTAGCCCTGCTTTGAAAGAATGCCACAG
yAlaThrCysLeuProLeuSerValArgArgSerThrThrTyrSerSerLeuHisAlaSe
|||||||||||||||||||||||||||||||||||||||||||||||||||||
rGluIleCysLeuProLeuSerValArgArgSerThrThrTyrSerSerLeuHisAlaSe
TGAAATTTGCTTACCGCTCTCTGTACGTCGATCTACCACCTACTCATCTCTTCATGCCTC
rGluAsnArgGluLeuLeuAsnValHisSerAlaAsnValSerLys<->ValSerPheAs
||||||| ||| ||| |||||| ||| ||
rGluAsnGlyGluThrLeuLysThrGluAsnGlyAsnValAlaLysAspPheAsnCysAs
CGAAAATGGAGAGACGTTGAAAACAGAAAATGGCAACGTCGCAAAAGATTTTAATTGTAA
nGluLysAlaValThrGluThrSerPheAsnSerValAsnValAsnGlyGlnArgGlyGl
|||| |||||| |||||||||||| ||| ||| ||| |||||
nGluGluValIleThrGluArgSerPheAsnSerIleAsnThrAsnAspGlnSerGlyGl
TGAGGAAGTCATAACTGAACGTTCCTTTAATTCCATAAATACTAATGACCAAAGTGGAGA
uAsnSerLysLeuSerLeuThrProAsnCysSerSerThrLeuAsnIleThrGlnSerGl
|||| |||||| |||||||||||| ||||||||||||||||||||||||
uAsn---LysLeuThrLeuThrProAsn---TyrSerThrLeuAsnIleThrGlnSerHi
GAAT---AAACTGACTCTTACCCCAAAC---TACTCAACTTTGAATATTACACAAAGCCA
nIleHisPheLeuSerProAspSerPheValAsnAsnSerHisGlyAlaAsnAsnGluLe
|||||||||||||||||||||||||||||||||||| ||||||||| ||
sThrHisPheLeuSerProAspSerPheValAsnAsnSerArgThrAlaAsnAsnGlyLe
CACACATTTCCTAAGTCCAGATTCTTTTGTAAATAATAGCCGTACAGCTAATAATGGGCT
uGluLeuValThrCysLeuSerSerAspMetPheMetLysAspAsnSerGlnProValHi
||||||||||||||||||| ||| |||||| ||||||||| ||||||
uGluLeuValThrCysLeuThrSerGluThrPheMetArgAspAsnSerLysProValTy
AGAATTAGTGACATGTCTTACATCAGAGACATTTATGAGAGATAATTCAAAGCCTGTATA
sLeuGluSerThrIleAlaHisGluIleTyrGlnLysIleLeuSerProAspSerPheIl
||||||||| ||| ||| |||||||||||| ||||||||
rLeuGluSerAsnThrValArgGluThrTyrArgThrIleLeuSerProAsnSerPheIl
TTTGGAATCTAACACTGTACGTGAAACTTATCGGACAATTTTAAGTCCAAATTCTTTTAT
eLysAspAsnTyrGlyLeuAsnGlnAspLeuGluSerGluSerValAsnProIleLeuSe
| ||| |||||| |||||| ||||||||||||||||||||||||||||||||
eAsnAspSerTyrGlyIleAsnGlnProLeuGluSerGluSerValAsnProIleLeuSe
AAATGATAGTTATGGAATAAATCAACCTCTAGAATCAGAGTCAGTAAATCCCATTTTATC
rProAsnGlnPheLeuLysAspAsnMetAlaTyrMetCysThrSerGlnGlnThrCysLy
|||| |||||| |||||||||||| ||| |||||||||||| ||||||||
rProHisGlnPheValLysAspAsnMetThrTyrIleCysThrSerGlnProThrCysLy
CCCACATCAATTTGTCAAAGACAATATGACATATATATGTACATCTCAGCCAACATGTAA
sValProLeuSerAsnGluAsnSerGlnValProGlnSerProGluAspTrpArgLysSe
| ||| |||||||||||
sLeuLeuSerSerProAsnGluAsnSerGlnIleProGluLeuGlnAsnTrpArgLysSe
ATTGCTATCATCACCAAATGAAAATTCTCAGATCCCAGAGCTTCAGAACTGGAGAAAAAG
rGluValSerProArgIleProGluCysGlnGlySerLysSerProLysAlaIlePheGl
||||||| ||| ||| ||||||||||||||||||||| |||||||||
rGluValLeuProCysIleSerLysCysGlnGlySerLysSerProGlnAlaIlePheLy
TGAAGTTTTGCCATGCATTTCTAAATGTCAGGGTTCAAAGTCTCCCCAAGCTATTTTCAA
uGluLeu<-><->ValGluMetLysSerAsnTyrTyrSerPheIleLysGlnAsnAsnPr
|||||| |||||| ||||||||| |||||| ||||||
sGluLeuLysAlaValGluThrLysSerAsnSerAsnSerPheThrAlaGlnAsnHisSe
AGAACTCAAAGCTGTAGAAACAAAGTCGAATAGCAACAGTTTCACAGCACAAAATCATTC
oLysPheSerAlaValGlnAspIleSerSerHisSerHisAsnLysGlnProLysArgAr
||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
rLysPheSerAlaValGlnAspIleSerSerHisSerHisLysLysGlnProLysArgAr
TAAATTTTCTGCAGTTCAGGATATTTCTAGTCACAGCCACAAAAAACAACCTAAGAGACG
gProIleLeuSerAlaThrValThrLysArgLysAlaThrCysThrArgGluAsnGlnTh
|||||||||||||||||||||||||||||||||| ||||||||| ||
gProIleLeuSerAlaThrValThrLysArgLysLeuIleHisAlaArgGluAsnLysTh
CCCAATACTTTCTGCCACTGTTACTAAAAGGAAGCTTATCCATGCCAGAGAAAACAAAAC
rGluIleAsnLysProLysAlaLysArgCysLeuAsnSerAlaValGlyGluHisGluLy
|||| |||||||||||||||||| ||||||||| |||||||||||| |||||
rGluMetAsnLysProLysAlaLysLysCysLeuAsnAsnAlaValGlyGluCysGluLy
TGAGATGAATAAACCGAAAGCAAAAAAATGTCTCAACAACGCAGTAGGTGAATGTGAAAA
sValIleAsnAsnGlnLysGluLysGluAspPheHisSerTyrLeuProIleIleAspPr
|||| |||||||||||| ||| |||||||||||||||||| ||
sValThrAspThrProLysGluLysGluAlaPheLeuSerTyrLeuProIleIleGluPr
AGTAACAGATACTCCAAAAGAGAAAGAAGCTTTTCTTTCTTATCTTCCAATTATAGAGCC
oIleLeuSerLysSerLysSerTyrLysAsnGluValThrProSerSerThrThrAlaSe
|||||||||||||||||||||||||||| |||||||||||| |||
oIleLeuSerLysSerLysSerTyrLysGluAlaValThrProSerMetValThr-----
AATATTAAGTAAATCTAAGAGTTATAAAGAAGCAGTGACTCCTTCAATGGTTACT-----
rValAlaArgLysArgLysSerAspGlySerMetGluAspAlaAsnValArgValAlaIl
|||||||||||||||||| ||| |||||||||||||||
-------ArgLysArgLysSerAspGluAsnLeuGluAlaAlaAsnValArgValValVa
-------CGTAAAAGAAAGAGTGATGAAAACCTGGAAGCTGCAAATGTGAGGGTTGTGGT
eThrGluHisThrGluValArgGluIleLysArgIleHisPheSerProSerGluProLy
||||||||| ||| ||||||||||||||||||||||||||||||||||||||
lThrGluHisIleGlyValGlnGluIleLysArgIleHisPheSerProSerGluProLy
TACAGAACACATAGGGGTGCAAGAAATCAAAAGAATTCATTTTTCTCCCTCTGAACCCAA
sThrSerAlaValLysLysThrLysAsnValThrThrProIleSerLysArgIleSerAs
||||||| ||||||||||||||| ||| ||||||||||||||| |||||
sThrSerThrValLysLysThrLysLysValIleThrProIleSerLys------SerAs
AACATCAACTGTAAAAAAAACAAAAAAGGTGATAACACCCATCTCAAAA------AGCAA
nArgGluLysLeuAsnLeuLysLysLysThr{A} >>>> Target Intron 3 >>>
||||||||||||| |||||||||||||||{|} 1039 bp
nArgGluLysLeuSerLeuLysLysLysThr{A}++
CAGAGAGAAATTAAGCCTGAAGAAGAAAACT{G}gt
> {sp}LeuSerIlePheArgThrProIleSerLysThrAsnLysArgThrLysProIl
{||} |||||| |||||| |||||| ||||||||||||||||||
++{sp}SerPheIlePheLysThrProThrSerLysProAsnLysArgThrLysProVa
ag{AT}TCATTCATATTCAAAACTCCTACTTCTAAACCAAACAAAAGGACAAAGCCCGT
eIleAlaValAlaGlnSerSerLeuThrPheIleLysProLeuLysThr{A} >>>> T
||||||||||||||||||||||||||||||||||||||||||||||||{|}
lIleAlaValAlaGlnSerSerLeuThrPheIleLysProLeuLysThr{A}+-
TATTGCTGTGGCACAGTCCAGTCTGACCTTCATAAAACCATTAAAAACA{G}gc
arget Intron 4 >>>> {sp}IleProArgHisProMetProPheAlaAlaLysAs
417 bp {||}|||||||||||||||||||||||||||||||||||
++{sp}IleProArgHisProMetProPheAlaAlaLysAs
ag{AT}ATTCCTAGACATCCAATGCCTTTTGCTGCAAAAAA
nMetPheTyrAspGluArgTrpLysGluLysGlnGluGlnGlyPheThrTrpTrpLeuAs
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nMetPheTyrAspGluArgTrpLysGluLysGlnGluGlnGlyPheThrTrpTrpLeuAs
CATGTTTTACGATGAACGTTGGAAGGAAAAACAGGAACAGGGCTTCACTTGGTGGCTAAA
nPheIleLeuThrProAspAspPheThrValLysThrAsnIleSerGlu{V} >>>> T
|||||||||||||||||||||||||||||||||||||||||||||||||{|}
nPheIleLeuThrProAspAspPheThrValLysThrAsnIleSerGlu{V}++
TTTTATATTAACTCCTGATGACTTCACTGTAAAAACAAATATTTCTGAA{G}gt
arget Intron 5 >>>> {al}AsnAlaAlaThrLeuLeuLeuGlyIleGluAsnGl
1253 bp {||}||||||||||||||| |||||| ||||||||
++{al}AsnAlaAlaThrLeuPheLeuGlyValGluAsnGl
ag{TA}AATGCTGCTACTCTCTTTTTGGGAGTAGAGAATCA
nHisLysIleSerValProArgAlaProThrLysGluGluMetSerLeuArgAlaTyrTh
||||||| |||||||||||||||||||||||| ||| |||||||||||||||||
nHisLysThrSerValProArgAlaProThrLysAspGluValSerLeuArgAlaTyrTh
ACATAAAACCAGTGTTCCTAGGGCACCTACGAAAGATGAAGTGTCTCTCCGAGCTTATAC
rAlaArgCysArgLeuAsnArgLeuArgArgAlaAlaCysArgLeuPheThrSerGluLy
||||||||||||| ||||||||||||||||||||||||||||||||||||||||||||
rAlaArgCysArgMetAsnArgLeuArgArgAlaAlaCysArgLeuPheThrSerGluLy
TGCGCGGTGCAGGATGAACAGGTTACGCCGTGCAGCTTGCCGTTTATTTACTTCTGAAAA
sMetValLysAlaIleLysLysLeuGluIleGluIleGluAlaArgArgLeuIleValAr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
sMetValLysAlaIleLysLysLeuGluIleGluIleGluAlaArgArgLeuIleValAr
AATGGTCAAGGCTATTAAAAAGCTTGAAATTGAAATTGAAGCTAGGCGGTTAATCGTTCG
gLysAspArgHisLeuTrpLysAspVal{G} >>>> Target Intron 6 >>>>
||||||||||||||||||||||||| {|} 1356 bp
gLysAspArgHisLeuTrpLysAspIle{G}++ ++
AAAAGATAGACACCTCTGGAAAGATATA{G}gt ag
{ly}GluArgGlnLysValLeuAsnTrpLeuLeuSerTyrAsnProLeuTrpLeuArgIl
{||}||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{ly}GluArgGlnLysValLeuAsnTrpLeuLeuSerTyrAsnProLeuTrpLeuArgIl
{GA}GAACGCCAGAAAGTCTTGAATTGGTTGTTGTCATATAATCCTCTGTGGCTTCGAAT
eGlyLeuGlu >>>> Target Intron 7 >>>> ThrThrTyrGlyGluLeuIle
|||||||||| 1360 bp ||| |||||||||||||||
eGlyLeuGlu++ ++ThrValTyrGlyGluLeuIle
TGGCCTAGAGgt agACAGTTTATGGAGAACTCATA
SerLeuGluAspAsnSerAspValThrGlyLeuAlaMetPheIleLeuAsnArgLeuLeu
|||||| ||||||||||||||||||||||||||||||||||||||||||||||||
AlaLeuGluGlyAsnSerAspValThrGlyLeuAlaMetPheIleLeuAsnArgLeuLeu
GCTTTGGAAGGCAACAGCGATGTCACAGGGCTGGCTATGTTTATTCTGAATCGCTTGCTT
TrpAsnProAspIleAlaAlaGluTyrArgHisProThrValProHisLeuTyrArgAsp
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
TrpAsnProAspIleAlaAlaGluTyrArgHisProSerValProHisLeuTyrArgAsp
TGGAATCCTGATATAGCAGCTGAGTATAGACACCCTTCTGTTCCTCATCTTTACAGAGAT
{G} >>>> Target Intron 8 >>>> {ly}HisGluGluAlaLeuSerLysPhe
{|} 1596 bp {||}||||||||||||||||||||||||
{G}++ ++{ly}HisGluGluAlaLeuSerLysPhe
{G}gt ag{GC}CATGAAGAAGCTTTGTCCAAGTTT
ThrLeuLysLysLeuLeuLeuLeuValCysPheLeuAspTyrAlaLysIleSerArgLeu
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
ThrLeuLysLysLeuLeuLeuLeuValCysPheLeuAspTyrAlaLysIleSerArgLeu
ACACTGAAAAAGTTATTGTTGTTGGTCTGTTTCCTTGACTATGCTAAAATTTCCAGACTT
IleAspHisAspProCysLeuPheCysLysAspAlaGluPheLys >>>> Target I
|||||||||||||||||||||||||||||||||||| |||||| 641
IleAspHisAspProCysLeuPheCysLysAspAlaLysPheLys++
ATTGATCATGATCCTTGTCTCTTCTGTAAAGATGCCAAATTCAAGgt
ntron 9 >>>> AlaSerLysGluIleLeuLeuAlaPheSerArgAspPheLeuSerG
bp ||||||||||||||||||||||||||||||||||||||||||||||
++AlaSerLysGluIleLeuLeuAlaPheSerArgAspPheLeuSerG
agGCAAGTAAGGAAATTCTTCTGGCTTTTTCACGTGATTTCCTAAGTG
lyGluGlyAspLeuSerArgHisLeuGlyLeuLeuGlyLeuProValAsnHisValGlnT
|||||||||||||||||||||||||| ||||||||||||||||||||||||||||
lyGluGlyAspLeuSerArgHisLeuSerPheLeuGlyLeuProValAsnHisValGlnT
GTGAAGGTGACCTTTCTCGTCACCTTAGCTTCCTGGGATTACCTGTTAACCATGTTCAGA
hrProPheAspGluPheAspPheAlaValThrAsnLeuAlaValAspLeuGlnCysGlyV
||||||||||||||||||||||| ||||||||||||||||||||||||||||||||||
hrProPheAspGluPheAspPheSerValThrAsnLeuAlaValAspLeuGlnCysGlyV
CACCATTTGATGAATTTGATTTTTCTGTTACAAATCTTGCTGTAGACTTGCAGTGCGGCG
alArgLeu{Va} >>>> Target Intron 10 >>>> {l}ArgThrMetGluLeu
||||||||{||} 2319 bp {|}|||||||||||||||
alArgLeu{Va}++ ++{l}ArgThrMetGluLeu
TGCGTCTT{GT}gt ag{G}AGAACCATGGAACTT
LeuThrGlnAsnTrpAspLeuSerLysLysLeuArgIleProAlaIleSerArgLeuGln
|||||||||||||||||||||||||||||||||||| |||||||||||||||||||||
LeuThrGlnAsnTrpAspLeuSerLysLysLeuArgLeuProAlaIleSerArgLeuGln
CTCACACAGAATTGGGATCTCTCAAAGAAACTCAGGCTTCCTGCAATAAGTCGTCTTCAA
LysMetHisAsnValAspIleValLeuGlnValLeuLysSerArgGlyIleGluLeuSer
||||||||||||||||||||||||||||||||||||||||||||||||||| |||
LysMetHisAsnValAspIleValLeuGlnValLeuLysSerArgGlyIleGlnLeuAsn
AAGATGCACAACGTGGACATTGTTCTTCAAGTTCTTAAGTCACGAGGAATTCAATTAAAT
AspGluHis{G} >>>> Target Intron 11 >>>> {ly}AsnThrIleLeuSe
|||||||||{|} 85 bp {||}||||||||||||||
AspGluHis{G}++ ++{ly}AsnThrIleLeuSe
GATGAGCAT{G}gt ag{GA}AATACAATTCTATC
rLysAspIleValAspArgHisArgGluLysThrLeuArgLeuLeuTrpLysIleAlaPh
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
rLysAspIleValAspArgHisArgGluLysThrLeuGlyLeuLeuTrpLysIleAlaPh
TAAGGACATAGTAGACAGACACAGAGAAAAAACTCTTGGGCTGCTTTGGAAAATAGCATT
eAlaPheGln >>>> Target Intron 12 >>>> ValAspIleSerLeuAsnLe
|||||||||| 531 bp ||||||||||||||||||||
eAlaPheGln++ ++ValAspIleSerLeuAsnLe
TGCTTTTCAGgt agGTGGATATTTCCCTTAATTT
uAspGlnLeuLysGluGluIleAlaPheLeuLysHisThrLysSerIleLysLysThrIl
|||||||||||||||||||||| ||||||||| |||||||||||||||
uAspGlnLeuLysGluGluIleAspPheLeuLysCysAlaArgSerIleLysLysThrMe
AGACCAATTAAAGGAAGAAATTGACTTTTTAAAATGTGCACGGAGTATAAAGAAAACAAT
eSerLeuLeuSerCysHisSerAspAspLeuIleAsnLysLysLysGlyLysArgAspSe
||| ||||||||| |||||| ||||||||||||||| ||| ||
tSerAlaLeuSerCysArgSerAspAlaValIleAsnLysLysLysGluLysMetAsnSe
GTCTGCACTATCTTGCCGATCTGATGCTGTTATTAATAAGAAAAAAGAAAAAATGAATAG
rGlySerPheGluGlnTyrSerGluAsnIleLysLeuLeuMetAspTrpValAsnAlaVa
|||| |||||||||||||||||| ||| ||||||||||||||||||||||||||
rGlyProPheGluGlnTyrSerGluLysIleAsnLeuLeuMetAspTrpValAsnAlaVa
TGGTCCTTTTGAGCAATATAGTGAAAAAATAAACTTATTGATGGATTGGGTAAATGCTGT
lCysAlaPheTyrAsnLysLys >>>> Target Intron 13 >>>> ValGluAs
||||||||||||||||||| 1926 bp ||||||||
lCysAlaPheTyrAsnLysGln++ ++ValGluAs
TTGTGCCTTCTACAATAAACAAgt agGTGGAGAA
nPheThrValSerPheSerAspGlyArgValLeuCysTyrLeuIleHisHisTyrHisPr
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nPheThrValSerPheSerAspGlyArgValLeuCysTyrLeuIleHisHisTyrHisPr
CTTCACAGTGTCATTCTCTGACGGCCGGGTGTTGTGTTACCTGATCCACCACTACCATCC
oCysTyrValProPheAspAlaIleCysGlnArgThrThrGlnThrValGluCysThrGl
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
oCysTyrValProPheAspAlaIleCysGlnArgThrThrGlnThrValGluCysThrGl
TTGCTATGTGCCTTTTGACGCTATATGCCAGCGCACTACTCAGACTGTGGAGTGCACCCA
nThrGlySerValValLeuAsnSerSerSerGluSerAspAspSerSerLeuAspMetSe
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
nThrGlySerValValLeuAsnSerSerSerGluSerAspAspSerSerLeuAspMetSe
GACCGGTTCCGTGGTGTTAAATTCATCGTCTGAATCCGATGATAGTTCTCTGGATATGTC
rLeuLysAlaPheAspHis{G} >>>> Target Intron 14 >>>> {lu}AsnT
|||||||||| {|} 96 bp {||}|||
rLeuLysAlaSerGluAsn{G}++ ++{lu}AsnA
TCTTAAAGCATCTGAAAAT{G}gt ag{AA}AATA
hrSerGluLeuTyrLysGluLeuLeuGluAsnGluLysLysAsnPheHisLeuValArgS
||| ||||||||||||||||||||||||||||||||||||||||||||| |
snSerGlyLeuTyrLysGluLeuLeuGluAsnGluLysLysAsnPheHisLeuIleSerS
ATTCAGGATTATACAAAGAACTCTTAGAAAATGAAAAGAAAAATTTTCATTTGATTAGCT
erAlaValArgAspLeuGlyGlyIleProAlaMetIleAsnHisSerAspMetSerAsnT
||||||||||||||||||||||| |||||||||||| |||||||||||||||||||
erAlaValArgAspLeuGlyGlyValProAlaMetIleHisHisSerAspMetSerAsnT
CTGCAGTAAGAGACCTTGGTGGAGTACCTGCTATGATTCATCATTCAGACATGTCAAATA
hrIleProAspGluLys >>>> Target Intron 15 >>>> ValValIleThrT
||||||||||||||||| 94 bp |||||||||||||
hrIleProAspGluLys++ ++ValValIleThrT
CAATTCCAGATGAAAAGgt agGTTGTTATTACCT
yrLeuSerPheLeuCysAlaArgLeuLeuAspLeuArgLysGluIleArgAlaAlaArgL
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
yrLeuSerPheLeuCysAlaArgLeuLeuAspLeuArgLysGluIleArgAlaAlaArgL
ATTTGTCGTTTCTTTGTGCAAGGCTTTTGGATCTTCGCAAAGAAATAAGAGCTGCTCGAC
euIleGlnThrThrTrpArgLysTyrLysLeuLysThrAspLeuLysArgHisGln >>
||||||||||| |||||||||||||||||||||||| |||||| ||||||
euIleGlnThrMetTrpArgLysTyrLysLeuLysThrTyrLeuLysTyrHisGln++
TTATACAAACCATGTGGAGAAAATATAAACTAAAAACGTACCTAAAATACCACCAGgt
>> Target Intron 16 >>>> GluArgGluLysAlaAlaArgIleIleGlnLeuA
783 bp |||||| ||||||||||||||||||||| |
++GluArgAspLysAlaAlaArgIleIleGlnSerA
agGAAAGAGACAAAGCTGCAAGAATTATTCAATCAG
laValIleAsnPheLeuAlaLysGlnArgLeuArgLysArgValAsnAlaAlaLeuValI
||||||||||||||||| ||| |||||| ||| ||| ||| |||||||
laValIleAsnPheLeuThrLysArgArgLeuLysLysGluValHisAlaValLeuValI
CTGTAATCAATTTTCTAACCAAACGACGACTGAAAAAAGAGGTTCATGCAGTGCTGGTCA
leGlnLysTyrTrpArgArgValLeuAlaGlnArgLysLeuLeuMetLeuLysLysGluL
|||||||| ||||||||| |||||||||||||||||| |||||||
leGlnLysHisTrpArgArgIleLeuAlaGlnArgLysLeu------------LysGluL
TTCAGAAACACTGGCGAAGAATCTTAGCACAGAGAAAATTA------------AAGGAAA
ysLeuGluLysValGlnAsnLysAlaAlaSerLeuIleGln >>>> Target Intro
||||||||||||||||||||||| |||||| |||||| 4532 bp
ysLeuGluLysValGlnAsnLysSerAlaSerValIleGln++
AACTGGAAAAAGTGCAAAATAAATCAGCATCTGTTATTCAGgt
n 17 >>>> GlyTyrTrpArgArgTyrSerThrArgGlnArgPheLeuLysLeuLysT
|||||||||||||||||||||||| ||||||||||||||||||
++ArgTyrTrpArgArgTyrSerThrArgLysArgPheLeuLysLeuLysH
agAGATATTGGAGAAGATACTCCACTAGAAAAAGATTTCTCAAGTTGAAAC
yrTyrSerIleIleLeuGlnSerArgIleArgMetIleIleAlaValThrSerTyrLysA
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
isTyrSerIleIleLeuGlnSerArgIleArgMetIleIleAlaValThrSerTyrLysA
ATTACTCAATCATCCTGCAATCTAGAATAAGAATGATAATTGCTGTCACATCTTATAAAC
rgTyrLeuTrpAlaThrValThrIleGlnArgHisTrpArgAlaTyrLeuArgArgLysG
|||||||||||||||||||||||||||||||| |||||||||||||||||||||||||
rgTyrLeuTrpAlaThrValThrIleGlnArgTyrTrpArgAlaTyrLeuArgArgLysG
GATATCTGTGGGCAACAGTTACAATTCAGAGATATTGGCGGGCTTATTTAAGAAGAAAAC
lnAspGlnGlnArgTyrGluMetLeuLysSerSerThrLeuIleIleGlnSerMetPheA
|||||||||||||||||||||||||| ||| |||||| |||||| ||||
lnAspGlnGlnArgTyrGluMetLeuArgSerAlaThrLeuValIleGlnAlaArgPheA
AAGATCAACAAAGATATGAAATGCTAAGATCAGCTACCCTTGTAATCCAGGCTAGGTTCA
rgLysTrpLysGlnArgLysMetGlnSerGlnValLysAlaThrValIleLeuGlnArgA
|| |||||| |||||| ||| ||||||||| |||||||||||||
rgArgTrpLysArgCysLysMetLeuLeuGlnIleLysAlaThrArgIleLeuGlnArgA
GAAGATGGAAGCGATGTAAGATGCTATTACAAATAAAAGCTACAAGAATATTACAAAGAG
laPheArgGluTrpHisLeuArgLysGlnAlaLysGluGluAsnSerAlaIleIleIleG
||||||||||||||||| |||||| |||||||||||| |||||| |||||||
laPheArgGluTrpHisPheArgLysArgAlaLysGluGluLysSerAlaValIleIleG
CTTTCAGAGAATGGCATTTCAGGAAACGCGCTAAAGAAGAAAAGTCTGCTGTTATCATAC
lnSerTrpTyrArgMetHisLysGluLeuArgLysTyrIleTyrIleArgSerCysValV
|||||||||||||||||||||||||||||||||||||| ||||||||||||||| |
lnSerTrpTyrArgMetHisLysGluLeuArgLysTyrMetTyrIleArgSerCysIleV
AGTCATGGTATAGAATGCACAAAGAACTGAGGAAATATATGTATATTAGATCTTGTATTG
alIleIleGlnLysArgPheArgCysPheGlnAlaGlnLysLeuTyrLysArgArgLysG
|| |||||| ||||||||||||||||||||||||||||||||||||||| ||||
alThrIleGlnArgArgPheArgCysPheGlnAlaGlnLysLeuTyrLysArgLysLysG
TTACCATTCAGAGAAGATTTCGGTGTTTTCAAGCCCAAAAATTATATAAAAGAAAAAAAG
luSerIleLeuThrIleGlnLysTyrTyrLysAlaTyrLeuLysGlyLysIleGluArgT
|| ||||||||||||||||||||| ||||||||| |||||| |||||||
luCysIleLeuThrIleGlnLysTyrPheArgAlaTyrLeuAsnGlyLysThrGluArgT
AGTGTATACTGACTATTCAGAAGTACTTCAGAGCATATCTGAATGGGAAGACGGAGCGCA
hrAsnTyrLeuGlnLysArgAlaAlaAlaIleGlnLeuGlnAlaAlaPheArgArgLeuL
|| |||||||||||||||||||||||| ||||||||||||||| ||||||
hrLysTyrLeuGlnLysArgAlaAlaAlaLeuGlnLeuGlnAlaAlaTyrArgArgMetG
CCAAGTATTTGCAGAAACGAGCTGCAGCCCTTCAGCTTCAGGCTGCTTATAGGAGAATGC
ysAlaHisAsnLeuCysArgGlnIleArgAlaAlaCysValIleGlnSerTyrTrpArgM
||| |||||| ||| ||||||||| ||| ||||||||||||||||
lnAlaArgAsnLeuHisArgArgAlaArgAlaAlaHisValLeuGlnSerTyrTrpArgM
AAGCTCGTAACTTACACAGACGAGCTAGAGCTGCTCATGTTCTTCAGTCATATTGGAGGA
etArgGlnAspArgValArgPheLeuAsnLeuLysLysThrIleIleLysPheGlnAlaH
|||||||| ||| |||||||||||||||||| |||||| |||||||
etArgGlnValArgLeuGlnPheLeuAsnLeuLysLysValValIleLysMetGlnAlaH
TGAGACAAGTCAGACTGCAATTTTTAAACCTCAAGAAGGTTGTTATCAAAATGCAGGCAC
isValArgLysHisGlnGlnArgGlnLysTyrLysLysMetLysLysAlaAlaValIleI
|| ||||||||||||||| ||||||||||||||||||||| |||||| |
isIleArgLysHisGlnGlnLeuGlnLysTyrLysLysMetLysGluAlaAlaLeuValI
ATATAAGAAAACATCAACAATTACAGAAATATAAGAAGATGAAGGAAGCAGCACTTGTAA
leGlnThrHisPheArgAlaTyrIlePheAlaMetLysValLeuAlaSerTyrGlnLysT
||||||||||||||||||||||| ||| ||||||||||||||||||||||
leGlnThrHisPheArgAlaTyrLeuSerAlaArgArgValLeuAlaSerTyrGlnLysT
TTCAGACCCATTTCCGAGCTTACCTTTCAGCCAGGAGAGTTCTGGCATCTTATCAGAAAA
hrArgSerAlaValIleValLeuGlnSerAlaTyrArgGlyMetGlnAlaArgLysMetT
|||||||||||||||||||||||||||||||||||||| ||| |||||||||
hrArgSerAlaValIleValLeuGlnSerAlaTyrArgArgMetLysAlaArgLysThrP
CTCGTTCTGCTGTCATTGTTTTACAGTCTGCATATAGAAGAATGAAAGCCAGGAAAACAT
yrIleHisIleLeuThrSerValIleLysIleGlnSerTyrTyrArgAlaTyrValSerL
||| ||||||||||||||| ||||||||||||||||||||||||||| |||
heIleArgIleLeuThrSerValValLysIleGlnSerTyrTyrArgAlaTyrIleSerA
TTATTCGGATTCTCACATCTGTTGTAAAGATTCAATCATATTATCGTGCTTATATTTCCA
ysLysGluPheLeuSerLeuLysAsnAlaThrIleLysLeuGlnSerThrValLysMetL
||| ||||||||||||||||||||||||||||||||||||||| ||||||||||
rgLysLysPheLeuSerLeuLysAsnAlaThrIleLysLeuGlnSerIleValLysMetL
GAAAGAAATTTCTGAGCCTGAAAAATGCTACAATAAAATTGCAATCAATTGTCAAGATGA
ysGlnThrArgLysGlnTyrLeuHisLeuArgAlaAlaAlaLeuPheIleGlnGlnCysT
|||||||||||||||||||||||||||||||| |||||| |||||||||||| |
ysGlnThrArgLysGlnTyrLeuHisLeuArgThrAlaAlaValPheIleGlnGlnTrpT
AGCAAACACGTAAACAATATTTACATTTAAGAACAGCTGCAGTGTTTATCCAGCAATGGT
yrArgSerLysLysIleAlaAlaGlnLysArgGluGluTyrMetGlnMetArgGluSerC
|||||||| ||||||||| |||||||||||||||||| ||||||||||||||||
yrArgSerGlnLysIleAlaThrGlnLysArgGluGluTyrThrGlnMetArgGluSerC
ACCGTTCCCAAAAAATAGCTACACAAAAGAGAGAAGAATATACACAGATGCGGGAATCTT
ysIleLysLeuGlnAlaPheValArgGlyTyrLeuValArgLysGlnMetArgLeuGlnA
||||||||||||||||| ||||||||| |||||||||||||||||| |||||||
ysIleLysLeuGlnAlaLeuValArgGlyPheLeuValArgLysGlnMetSerLeuGlnA
GTATCAAGCTGCAAGCTTTGGTTAGAGGCTTCCTGGTCCGAAAGCAGATGAGTTTGCAAA
rgLysAlaValIleSerLeuGlnSerTyrPheArgMetArgLysAlaArgGlnTyrTyrL
|||||||| |||||||||||||||||||||||||||||| |||||| ||||
rgLysAlaAlaValSerLeuGlnSerTyrPheArgMetArgLysMetArgGlnHisTyrL
GAAAAGCTGCTGTTTCACTCCAGTCTTATTTCAGAATGAGAAAGATGCGGCAGCACTACT
euLysMetTyrLysAlaIleIleValIleGlnAsnTyrTyrHisAlaTyrLysAlaGlnV
||||| ||||||||| ||||||||| |||||||||||||||||| |
euLysIleTyrLysAlaThrAlaValIleGlnLysHisTyrHisAlaTyrLysAlaArgV
TGAAAATTTATAAGGCAACTGCTGTCATCCAGAAACACTATCATGCATACAAAGCACGAG
alAsnGlnArgLysAsnPheLeuGlnValLysLysAlaAlaThrCysLeuGlnAlaAlaT
|| |||||||||||||||||||||||| |||||||||||||||||||||||||
alTyrGluArgLysAsnPheLeuGlnValLysArgAlaAlaThrCysLeuGlnAlaAlaT
TCTACGAGAGGAAGAACTTCTTGCAAGTCAAAAGAGCAGCGACTTGTCTGCAAGCAGCTT
yrArgGlyTyrLysValArgGlnLeuIleLysGlnGlnSerIleAlaAlaLeuLysIleG
|||||||||||||||||||||||||||||||| |||||| ||||||||||||||||
yrArgGlyTyrLysValArgGlnLeuIleLysArgGlnSerValAlaAlaLeuLysIleG
ACAGAGGCTATAAAGTGCGCCAACTCATAAAACGACAATCTGTAGCCGCACTTAAAATTC
lnSerAlaPheArgGlyTyrAsnLysArgValLysTyrGlnSerValLeuGlnSerIleI
|| ||||||||| |||||||||||||||||||||||||||||||||
lnAlaValPheArgGlyHisSerLysArgValLysTyrGlnSerValLeuGlnSerAlaV
AAGCTGTCTTTAGGGGGCATAGTAAAAGGGTGAAATATCAGTCTGTGCTGCAGTCTGCTG
leLysIleGlnArgTrpTyrArgAlaTyrLysThrLeuHisAspThrArgThrHisPheL
||||||||||||||||||||||||||||||||| |||||||||||||
alLysIleGlnArgTrpTyrArgAlaTyrLysThrValTyrAsnValArgThrHisPheL
TGAAGATTCAGAGATGGTACAGGGCATACAAGACTGTTTATAATGTAAGAACACATTTTT
euLysThrLysAlaAlaValIleSerLeuGlnSerAlaTyrArgGlyTrpLysValArgL
||||| |||||||||||||||||||||||||||||||||||||||||||||||||
euLysMetArgAlaAlaValIleSerLeuGlnSerAlaTyrArgGlyTrpLysValArgL
TGAAGATGAGAGCAGCTGTGATTTCTCTCCAGTCAGCCTACCGTGGCTGGAAAGTTCGGA
ysGlnIleArgArgGluHisGlnAlaAlaLeuLysIleGlnSerAlaPheArgMetAlaL
||||||||||||||||| ||||||||| |||||||||||| |||||||||
ysGlnIleArgArgGluGlnGlnAlaAlaMetLysIleGlnSerCysPheArgMetValA
AACAGATCAGAAGGGAACAGCAAGCTGCAATGAAGATTCAGTCTTGTTTTAGGATGGTCA
ysAlaGlnLysGlnPheArgLeuPheLysThrAlaAlaLeuValIleGlnGlnAsnPheA
||||||||||||||||||||| ||||||||| |||||||||||| |
rgAlaGlnLysGlnPheArgLeuLeuLysThrAlaValIleValIleGlnGlnHisLeuA
GGGCCCAGAAACAGTTCAGATTGTTAAAAACAGCAGTAATAGTCATCCAACAACATCTGA
rgAlaTrpThrAlaGlyArgLysGlnCysMetGluTyrIleGluLeuArgHisAlaValL
||||||||||||||||| |||||| ||||||||| ||||||||| |||||||
rgAlaTrpThrAlaGlyLysLysGlnArgMetGluTyrLeuGluLeuArgArgAlaValL
GAGCATGGACCGCAGGAAAGAAACAACGTATGGAGTATCTTGAACTCCGTCGTGCAGTCC
euValLeuGlnSerMetTrpLysGlyLysThrLeuArgArgGlnLeuGlnArgGlnHisL
|| ||||||||| ||||||||| ||||||||||||||| |||||||||||||
euIleLeuGlnSerAlaTrpLysGlyArgThrLeuArgArgGlnIleGlnArgGlnHisL
TGATACTTCAGTCTGCCTGGAAGGGAAGGACACTGAGAAGACAGATTCAAAGGCAACACA
ysCysAlaIleIleIleGlnSerTyrTyrArgMetHisValGlnGlnLysLysTrpLysI
|||||||| |||||||||||||||||||||||| ||||||||| |||||||||
ysCysAlaValIleIleGlnSerTyrTyrArgMetTyrValGlnGlnGlnLysTrpLysS
AGTGTGCTGTCATCATTCAGTCATACTATAGGATGTACGTGCAACAACAGAAGTGGAAAT
leMetLysLysAlaAlaLeuLeuIleGlnLysTyrTyrArgAlaTyrSerIleGlyArgG
||||||||||||||||||||||||||| |||||||||||||||||| ||||||
erMetLysLysAlaAlaLeuLeuIleGlnMetTyrTyrArgAlaTyrSerThrGlyArgL
CCATGAAAAAAGCTGCTCTTCTGATTCAAATGTATTATAGGGCTTACAGTACTGGAAGAA
luGlnAsnHisLeuTyrLeuLysThrLysAlaAlaValValThrLeuGlnSerAlaTyrA
||| |||||||||||||||||||||||| ||| ||||||||| ||||
ysGlnHisArgLeuTyrLeuLysThrLysAlaAlaAlaValValLeuGlnSerThrTyrA
AACAGCATCGATTATATCTGAAAACAAAAGCAGCTGCAGTAGTTTTACAGTCCACATATC
rgGlyMetLysValArgLysArgIleLysAspCysAsnLysAlaAlaValThrIleGlnS
||||| |||||||||||||||||||||||||||||||||||||||||||||||||||
rgGlyLysLysValArgLysArgIleLysAspCysAsnLysAlaAlaValThrIleGlnC
GGGGTAAGAAAGTGAGAAAAAGAATAAAGGATTGCAACAAAGCAGCAGTCACTATTCAGT
erLysTyrArgAlaTyrLysThrLysLysLysTyrAlaThrTyrArgAlaSerAlaIleI
||||||||||||||| |||||||||||| ||||||||||||||||||
ysThrTyrArgAlaTyrLysAlaArgLysLysTyrAlaMetTyrArgAlaSerAlaIleT
GTACATATAGAGCTTATAAAGCCAGAAAGAAATATGCAATGTATAGAGCTTCAGCTATTA
leIleGlnArgTrpTyrArgGlyIleLysIleThrAsnHisGlnHisLysGluTyrLeuA
|||||||||||||||||||||||| ||| ||| ||| |||||||||
hrIleGlnArgTrpTyrArgGlyIleThrIleAlaSerHisLeuHisGluGluTyrLeuT
CAATTCAGAGATGGTATAGAGGTATTACAATTGCAAGCCATCTACATGAGGAATATCTTA
snLeuLysLysThrAlaIleLysIleGlnSerValTyrArgGlyIleArgValArgArgH
||||||||||||||| ||||||||| ||||||||||||||||||||||||||||
hrLeuLysLysThrAlaValLysIleGlnAlaValTyrArgGlyIleArgValArgArgH
CTTTAAAGAAGACTGCAGTTAAAATCCAAGCCGTTTATAGAGGGATTAGAGTAAGAAGAC
isIleGlnHisMetHisArgAlaAlaThrPheIleLysAlaMetPheLysMetHisGlnS
||||| ||||||||| ||||||||||||||||||||| ||||||||||||||||
isIleLysHisMetHisMetAlaAlaThrPheIleLysAlaThrPheLysMetHisGlnS
ATATTAAACACATGCACATGGCAGCCACTTTTATTAAAGCCACATTTAAAATGCATCAGT
erArgIleSerTyrHisThrMetArgLysAlaAlaIleValIleGlnValArgCysArgA
||||| |||||| |||||| |||||||||||||||||||||||| ||||
erArgValLysTyrHisLysMetArgThrAlaAlaIleValIleGlnValArgTyrArgA
CAAGAGTGAAATACCATAAAATGAGAACAGCGGCTATTGTCATTCAAGTAAGATATAGAG
laTyrTyrGlnGlyLysMetGlnArgGluLysTyrLeuThrIleLeuLysAlaValLysV
|||||||||||||| ||||||||||||||||||||||||||||||||| |
laTyrTyrGlnGlyArgValGlnArgGluLysTyrLeuThrIleLeuLysAlaIleHisV
CATATTATCAAGGTAGAGTTCAGCGTGAAAAGTATCTGACAATTTTGAAAGCCATCCATG
alLeuGlnAlaSerPheArgGlyValArgValArgArgThrLeuArgLysMetGlnThrA
||||||||||||||||||||||| ||||||||| ||||||||||||||| |
alLeuGlnAlaSerPheArgGlyAlaArgValArgGlnSerLeuArgLysMetGlnIleA
TTCTTCAGGCAAGTTTTAGAGGAGCGAGAGTTAGACAGAGTCTAAGAAAGATGCAGATTG
laAlaThrLeuIleGlnSerAsnTyrArgArgTyrArgGlnGlnThrTyrPheAsnLysL
|||||||||||||||||||| ||||||||| |||||| |||||||||||||
laAlaThrLeuIleGlnSerTyrTyrArgArgHisLysGlnGlnAlaTyrPheAsnLysL
CAGCCACACTCATTCAGTCATACTATAGAAGACACAAACAACAAGCATATTTTAATAAGT
euLysLysIleThrLysThrValGlnGlnArgTyrTrpAlaMetLysGluArgAsnIleG
||||| ||| |||||||||||||||||| ||| |||||||||||| |
euLysArgValThrGluThrValGlnGlnArgTyrArgAlaLeuLysGluArgAsnMetG
TAAAAAGGGTAACAGAAACAGTACAACAAAGATATCGGGCACTGAAGGAAAGAAACATGC
lnPheGlnArgTyrAsnLysLeuArgHisSerValIleTyrIleGlnAlaIlePheArgG
|||||||||||||||||||||||||||||||||||||| ||||||||| |||||||
lnPheGlnArgTyrAsnLysLeuArgHisSerValIleArgIleGlnAlaGlyPheArgG
AGTTTCAAAGGTATAACAAATTGAGGCATTCTGTGATACGCATTCAGGCTGGTTTCAGGG
lyLysLysAlaArgArgHisLeuLysMetMetHisIleAlaAlaThrLeuIleGlnArgA
|| ||| ||||||||||||||| |||||| ||||||||||||||||||||||
lyTrpLysValArgArgHisLeuLysIleMetHisLeuAlaAlaThrLeuIleGlnArgA
GCTGGAAAGTTAGACGACATTTGAAGATTATGCATCTAGCTGCAACCCTTATTCAGAGAA
rgPheArgThrLeuMetMetArgArgArgPheLeuSerLeuLysLysThrAlaIleLeuI
|||||||| |||||||||||||||||||||||||||||| |||||| |
rgPheArgMetLeuMetMetArgArgArgPheLeuSerLeuArgLysThrValValTrpI
GATTTAGAATGCTAATGATGAGAAGAAGATTCCTATCGCTCAGGAAAACTGTTGTTTGGA
leGlnArgLysTyrArgAlaHisLeuCysThrLysHisHisLeu<->GlnPheLeuGlnV
|||||||||||||||||||| ||| ||||||||| |||||||||
leGlnArgLysTyrArgAlaAsnLeuHisAlaArgHisHisLeuArgGlnPheLeuTrpL
TTCAGAGAAAATATCGTGCAAATCTTCATGCCAGACATCACTTACGACAGTTCCTTTGGT
alGlnAsnAlaValIleLysIleGlnSerSerTyrArgArgTrpMetIleArgLysArgM
||| ||||||||||||||| |||||| ||| |||||| |
euArgLysAlaIleIleLysIleGlnSerLeuTyrArgGlyTrpThrValArgLysLysM
TACGAAAGGCAATTATTAAAATCCAGTCATTATACAGAGGATGGACAGTAAGGAAGAAGA
etArgGluMetHisArgAlaAlaThrPheIleGlnSerThrPheArgMetHisArgLeuH
|||||||||||||| |||||| |||||| |||||| |||||||||
etArgGluMetHisMetAlaAlaAlaCysIleGlnAlaThrPheLysMetHisArgAlaA
TGCGAGAGATGCACATGGCTGCTGCTTGTATCCAGGCTACTTTCAAAATGCACAGAGCAC
isMetArgTyrGlnAlaLeuLysGlnAlaSerValValIleGlnGlnGlnTyrGlnAlaA
||| |||||||||||||||||||||||||||||||||||| ||| |||
rgValArgHisGlnAlaLeuLysGlnAlaSerValValIleGlnGlnArgTyrArgAlaT
GTGTGAGACACCAGGCTTTGAAACAGGCCTCAGTCGTGATCCAACAGAGATACCGAGCAA
snArgAlaAlaLysLeuGlnArgGlnHisTyrLeuArgGlnArgHisSerAlaValIleL
||||||||||||||||||||||||||||||||| ||||||||||||||||||||||
hrArgAlaAlaLysLeuGlnArgGlnHisTyrLeuGlnGlnArgHisSerAlaValIleL
CCAGAGCCGCGAAACTGCAGAGGCAGCATTACCTCCAACAAAGACATTCAGCCGTGATCC
euGlnAlaAlaPheArgGlyMetLysThrArgArgHisLeuLysSerMetHisSerSerA
|||||||||||||||||||||||||| ||||||||| ||| |||||||||||||
euGlnAlaAlaPheArgGlyMetLysAlaArgArgHisGlnLysArgMetHisSerSerA
TGCAGGCTGCATTTAGGGGCATGAAAGCTAGAAGACATCAGAAAAGGATGCATTCCTCTG
laThrLeuIleGlnSerArgPheArgSerLeuLeuValArgArgArgPheIleSerLeuL
|||||||||||||||||||||||||||||||| ||||||||||||||| |||||||
laThrLeuIleGlnSerArgPheArgSerLeuValValArgArgArgPheLeuSerLeuL
CGACCCTTATTCAGAGTAGGTTTAGATCATTAGTGGTGAGGAGAAGATTCCTCTCACTCA
ysLysAlaThrIlePheValGlnArgLysTyrArgAlaThrIleCysAlaLysHisLysL
|| ||| ||| ||||||||||||||||||||||||||||||||||||||| |
ysGluAlaAlaIleSerValGlnArgLysTyrArgAlaThrIleCysAlaLysHisGlnL
AGGAAGCTGCTATTTCTGTTCAGAGGAAATACCGAGCCACCATTTGTGCCAAGCATCAGT
euTyrGlnPheLeuHisLeuArgLysAlaAlaIleThrIleGlnSerSerTyrArgArgL
|| ||||||||| |||||||||||||||||| ||||||||||||||||||||||
euHisGlnPheLeuGlnLeuArgLysAlaAlaIleValIleGlnSerSerTyrArgArgL
TGCACCAGTTCCTGCAGTTACGAAAGGCAGCCATTGTGATTCAGTCATCGTACCGAAGAC
euMetValLysLysLysLeuGlnGluMetGlnArgAlaAlaValLeuIleGlnAlaThrP
|| |||||| ||||||||||||||||||||||||||||||||||||||||||||||
euIleValLysArgLysLeuGlnGluMetGlnArgAlaAlaValLeuIleGlnAlaThrP
TGATAGTAAAGAGGAAGTTACAAGAAATGCAAAGGGCCGCGGTTCTCATTCAGGCTACTT
heArgMetTyrArgThrTyrIleThrPheGlnThrTrpLysHisAlaSerIleLeuIleG
|||||||| ||||||||| ||||||||||||||| |||||| |||||||
heArgMetHisArgThrTyrValAlaPheGlnThrTrpLysGlnAlaSerValLeuIleG
TCCGAATGCACAGAACATACGTGGCATTTCAGACTTGGAAACAGGCCTCAGTTCTAATTC
lnGlnHisTyrArgThrTyrArgAlaAlaLysLeuGlnArgGluAsnTyrIleArgGlnT
|| ||||||||||||||||||||||||||||||||||||||||||||||||||| |
lnArgHisTyrArgThrTyrArgAlaAlaLysLeuGlnArgGluAsnTyrIleArgArgT
AGCGACATTATCGGACATATAGAGCTGCAAAATTGCAAAGAGAAAATTATATTAGACGAT
rpHisSerAlaValValIleGlnAlaAlaTyrLysGlyMetLysAlaArgGlnLeuLeuA
|| |||||| ||||||||| ||||||||||||||||||||||||||||||||||
rpArgSerAlaIleValIleGlnSerAlaTyrLysGlyMetLysAlaArgGlnLeuLeuA
GGCGTTCTGCCATTGTCATTCAGTCTGCATACAAAGGAATGAAAGCAAGACAGCTTTTGA
rgGluLysHisLysAlaSerIleValIleGlnSerThrTyrArgMetTyrArgGlnTyrC
||||| ||| ||| ||||||||||||||||||||||||||| |||
rgGluArgHisArgAlaAlaValIleIleGlnSerThrTyrArgMetTyrArgHisTyrT
GGGAAAGACACAGAGCTGCTGTCATAATACAAAGCACTTATAGAATGTATAGGCACTACT
ysPheTyrGlnLysLeuGlnTrpAlaThrLysIleIleGlnGluLysTyrArgAlaAsnL
||||||||| |||||||||||| ||| |||||||||||||||||| ||||
yrPheTyrGlnArgLeuGlnTrpAlaAlaLysValIleGlnGluLysTyrArgGluAsnL
ATTTCTACCAAAGGCTTCAGTGGGCTGCAAAAGTAATACAAGAAAAATATAGAGAAAATA
ysLysLysGlnLysValPheGlnHisAsnGluLeuLysLys<->GluThrCysValGlnA
||||||||||| ||| |||||||||||| ||| ||||
ysLysLysGlnThrAlaLeuGlnProGlyGluLeuLysLysAlaAlaThrPheThrGlnA
AAAAGAAACAGACAGCTCTTCAACCCGGTGAACTTAAGAAAGCAGCAACTTTTACTCAGG
laGlyPheGlnAspMetAsnIleLysLysGlnIleGlnGluGlnHisGlnAlaAlaIleI
||||||||||||||||||||||| ||| |||||| |||||||||||||||||||
laGlyPheGlnAspMetAsnIleSerLysHisIleGlnLysGlnHisGlnAlaAlaIleI
CAGGTTTTCAGGACATGAACATCAGCAAACACATTCAGAAACAACATCAGGCTGCCATTA
leIleGlnLysHisCysLysAlaPheLysIleArgLysHisTyrLeuHisLeuArgAlaT
|| ||||||||| ||| ||| ||| ||||||||||||||||||||||
leValGlnLysHisPheLysThrPheGlnMetArgArgHisTyrLeuHisLeuArgAlaT
TTGTTCAGAAGCACTTCAAAACCTTTCAAATGAGGAGGCATTATCTCCACCTTAGAGCAA
hrValValSerIleGlnArgArgTyrArgLysLeuThrAlaValArgThrGlnAlaValI
||||||||||||||||||||||||||||| ||| ||| ||||||
hrValValSerIleGlnArgArgTyrArgAlaArgAlaAlaMetArgAsnGlnAlaAlaT
CAGTAGTTTCTATTCAAAGAAGATACAGAGCACGCGCAGCAATGCGTAACCAAGCAGCTA
leCysIleGlnSerTyrTyrArgGlyPheLysValArgLysAspIleGlnAsnMetHisA
||||||||| ||||||||||||||| ||| |||||| ||||||
hrCysIleGlnAlaSerTyrArgGlyPheLysAlaArgArgHisIleGlnGlnMetHisL
CTTGTATACAGGCTTCTTACAGAGGCTTTAAGGCACGAAGGCATATACAGCAGATGCACC
rgAlaAlaThrLeuIleGlnSerPheTyrArgMetHisArgAlaLysValAspTyrGluT
||||||||||||||||||||| |||||||||||||||||| ||||||
euAlaAlaThrLeuIleGlnSerLeuTyrArgMetHisArgAlaGlnGlyAspTyrArgA
TGGCTGCCACACTAATTCAGTCACTCTACCGAATGCACAGGGCCCAAGGTGACTATCGAG
hrLysLysThrAlaIleValValIleGlnAsnTyrTyrArgLeuTyrValArgValLysT
||||||||||||||| |||||||||||||||||| ||| ||||||
laLysLysThrAlaIleAlaIleIleGlnAsnTyrTyrArgSerTyrAlaSerValLysA
CAAAGAAAACTGCAATTGCTATTATACAGAATTATTATAGGTCATATGCCAGTGTGAAAA
hrGluArgLysAsnPheLeuAlaValGlnLysSerValArgThrIleGlnAlaAlaPheA
||||||||| |||||| |||||||||||||||||||||||||||||||||||||
rgGluArgLysGlnPheLeuValValGlnLysSerValArgThrIleGlnAlaAlaPheA
GGGAACGAAAACAATTTTTAGTGGTTCAGAAATCTGTACGAACCATTCAGGCTGCTTTTA
rgGlyMetLysValArgGlnLysLeuLysAsnValSerGluGluLysMetAlaAlaIleV
||||||||||||||||||||||||||||| |||||| ||| ||||||
rgGlyMetLysValArgGlnLysLeuLysThrIleSerGluGlyLysThrThrAlaIleA
GAGGCATGAAAGTTCGACAGAAATTGAAAACCATATCTGAGGGAAAGACAACAGCCATTG
alAsnGlnSerAlaLeuCysCysTyrArgSerLysThrGlnTyrGluAlaValGlnSerG
|||||||||||| ||| |||||||||||| |||||||||
laAsnGlnSerAlaPheSerCysLeuGlyThrGluThrGlnTyrGluThrValGlnSerG
CTAACCAATCTGCATTCTCCTGTCTCGGAACTGAAACCCAATATGAAACTGTTCAAAGTG
luGlyValMetIleGlnGluTrpTyrLysAlaSerGlyLeuAlaCysSerGlnGluAlaG
|||||||||||| |||||| |||||||||||||
lyGlyValMetIleArg---------AsnArgThrSerLeuAlaSerSerGlnGluAlaG
GGGGTGTTATGATTCGA---------AATAGAACTTCACTTGCCAGTTCACAGGAAGCAG
luTyrHisSerGlnSerArgAlaAlaValThrIleGlnLysAlaPheCysArgMetValT
||||||||||||||||| |||||||||||| |||||||||||| |||||||
luTyrHisSerGlnSerThrAlaAlaValThrArgGlnLysAlaPheGlnLysMetValT
AGTATCATTCTCAAAGTACAGCTGCAGTCACAAGGCAAAAAGCTTTTCAGAAAATGGTCA
hrArgLysLeuGluThrGlnLysCysAlaAlaLeuArgIleGlnPhePheLeuGlnMetA
|||||||||||||||||||||||||||||||| |||||| |||||||||||||
hrArgLysLeuGluThrGlnLysCysAlaAlaValGlnIleGlnSerPheLeuGlnMetA
CAAGAAAACTGGAAACTCAGAAATGTGCTGCCGTACAAATTCAGTCCTTTCTTCAGATGG
laValTyrArgArgArgPheValGlnGlnLysArgAlaAlaIleThrLeuGlnHisTyrP
|| |||||||||||| |||||| ||||||||| ||||||||| ||||
laMetCysArgArgArgPheIleGlnGlnArgArgAlaAlaValThrLeuGlnArgTyrP
CCATGTGTCGACGAAGGTTCATCCAGCAGAGAAGAGCTGCTGTCACTTTACAGCGTTACT
heArgThrTrpGlnThrArgLysGlnPheLeuLeuTyrArgLysAlaAlaValValLeuG
||||||||||||||||||||||||||||||||||||||||||||||| ||||||||||
heArgThrTrpGlnThrArgLysGlnPheLeuLeuTyrArgLysAlaValValValLeuG
TCAGGACATGGCAAACCAGAAAACAATTTTTACTGTATAGAAAAGCAGTGGTGGTTTTAC
lnAsnHisTyrArgAlaPheLeuSerAlaLysHisGlnArgGlnValTyrLeuGlnIleA
|| ||| |||||||||||||||||| |||||||||||||||||||||||||
lnHisHisHisArgAlaPheLeuSerAlaArgGlnGlnArgGlnValTyrLeuGlnIleA
AACATCACCACCGAGCCTTTCTGTCTGCCCGACAGCAAAGACAGGTGTATTTACAAATCA
rgSerSerValIleIleIleGlnAlaArgSerLysGlyPheIleGlnLysArgLysPheG
|| |||||| |||||||||||| |||||||||||||||||||||||||
rgArgAsnValIleMetIleGlnAlaArgThrArgGlyPheIleGlnLysArgLysPheG
GACGCAACGTTATCATGATTCAAGCTAGAACGAGAGGATTTATACAGAAACGGAAATTTC
lnGluIleLysAsnSerThrIleLysIleGln >>>> Target Intron 18 >>>>
|| |||||| |||||||||||||||||| 3703 bp
lnLysIleLysSerSerThrIleLysIleGln++
AGAAAATTAAAAGTAGCACCATAAAAATTCAGgt
AlaMetTrpArgArgTyrArgAlaLysLysTyrLeuCysLysValLysAlaAlaCysL
||| |||||||||||| |||||| |||||| |||||||||||||||||||
++AlaValTrpArgArgTyrLysAlaLysThrTyrLeuSerLysValLysAlaAlaCysL
agGCTGTATGGAGGAGATATAAAGCCAAAACGTATTTATCTAAAGTGAAAGCTGCCTGCA
ysIleGlnAlaTrpTyrArgCysTrpArgAlaHisLysGluTyrLeuAlaIleLeuLysA
|||||||||||||||||||||||||||||||| ||||||||||||||| ||| |
ysIleGlnAlaTrpTyrArgCysTrpArgAlaArgLysGluTyrLeuAlaValLeuGlnA
AAATTCAAGCCTGGTATAGATGTTGGAGAGCACGCAAAGAATATCTAGCTGTATTACAAG
laValLysIleIleGlnGlyCysPheTyrThrLysLeuGluArgThr{Ar} >>>> Ta
||||| |||||||||||| ||||||||||||||| {||}
laValArgPheIleGlnGlyCysIleArgThrLysLeuGluArgAla{Ar}++
CTGTGAGATTTATTCAGGGTTGCATCCGTACCAAATTGGAGAGAGCA{CG}gt
rget Intron 19 >>>> {g}PheLeuAsnValArgAlaSerAlaIleIleIleGln
1695 bp {|}||||||||| ||||||||||||||| ||||||
++{g}PheLeuAsnMetArgAlaSerAlaIleValIleGln
ag{G}TTTTTGAATATGAGAGCATCAGCAATTGTCATTCAG
ArgLysTrpArgAlaIleLeuProAlaLysIleAlaHisGluHisPheLeuMetIleLys
||||||||||||||| ||| ||| ||| ||||||||| ||| |||
ArgLysTrpArgAlaThrLeuAlaAlaArgGlnAlaArgGluHisPheIleMetThrLys
AGAAAGTGGAGAGCTACACTTGCTGCAAGACAAGCTCGTGAGCACTTCATAATGACAAAA
>>>> Target Intron 20 >>>> ArgHisArgAlaAlaCysLeuIleGlnAla
1140 bp |||||||||||||||||||||||||||
++ ++SerHisArgAlaAlaCysLeuIleGlnAla
gt agAGCCATCGAGCTGCTTGTTTGATCCAAGCA
HisTyrArgGlyTyrLysGlyArgGlnValPheLeuArgGlnLysSerAlaAlaLeuIle
||| |||||||||||||||||||||||||||||| |||||||||||||||||||||
HisPheArgGlyTyrLysGlyArgGlnValPheLeuGlnGlnLysSerAlaAlaLeuIle
CATTTTAGAGGCTATAAAGGAAGGCAGGTCTTCCTTCAGCAGAAATCTGCTGCTTTGATC
IleGlnLysTyrIleArgAlaArgGluAlaGlyLysHisGluArgIleLysTyrIleGlu
||| ||||||||||||||||||||||||||| ||||||||||||||| |||
IleHisArgTyrIleArgAlaArgGluAlaGlyLysTyrGluArgIleLysTyrValGlu
ATACACAGATATATACGAGCCAGGGAGGCTGGGAAATATGAAAGGATAAAATATGTTGAA
PheLysLysSerThrValIleLeuGlnAlaLeuValArgGlyTrpLeuValArgLysArg
||| ||||||||| |||||||||||| |||||||||||||||||||||
Phe***IleSerThrValValLeuGlnAlaLeu------GlyTrpLeuValArgLysArg
TTTTAAATATCCACAGTTGTTCTACAAGCACTG------GGTTGGTTAGTAAGAAAAAGA
>>>> Target Intron 21 >>>> PheLeuGluGlnArgAlaLysIleArgLeu
1835 bp ||||||||||||||||||||||||
++ ++IleLeuGluGlnArgAlaLysIleArgArg
gt agATTTTGGAACAGAGAGCCAAAATTCGGCGT
LeuHisPheThrAlaAlaAlaTyrTyrHisLeuAsnAlaValArgIleGlnArgAlaTyr
||||||||||||||||||||||||||||||||| ||| ||||||||||||||||||
LeuHisPheThrAlaAlaAlaTyrTyrHisLeuSerAlaIleArgIleGlnArgAlaTyr
CTTCACTTCACAGCAGCTGCCTATTATCACCTGTCTGCTATTAGAATTCAAAGAGCATAT
LysLeuTyrLeuAlaValLysAsnAlaAsnLysGlnValAsnSerValIleCysIleGln
||||||||| ||||||||||||||| |||||| |||||||||||||||||||||
LysLeuTyrMetAlaValLysAsnAlaLysLysGlnLeuAsnSerValIleCysIleGln
AAACTTTACATGGCAGTGAAGAATGCTAAAAAGCAGCTTAATTCAGTCATCTGTATCCAG
>>>> Target Intron 22 >>>> ArgTrpPheArgAlaArgLeuGlnGluLys
1124 bp |||||||||||||||||| ||| |||
++ ++ArgTrpPheArgAlaArgIleGlnHisLys
gt agAGATGGTTTCGAGCAAGAATACAACACAAG
ArgPheIleGlnLysTyrHisSerIleLysLysIleGluHisGluGlyGlnGluCysLeu
||||||||| ||| ||||||||| |||||| |||
LysMetIleGlnLysSerHisAsnValIleGluValGluHisGluValGlnGluHisLeu
AAGATGATTCAGAAGTCTCATAACGTCATAGAAGTGGAGCATGAAGTTCAAGAACATCTG
SerGlnArgAsnArgAlaAlaSerValIleGlnLysAlaValArgHisPheLeuLeuArg
||| ||||||||||||||||||||||||||||||||| |||||||||
AsnGlnGlnHisArgAlaAlaSerValIleGlnLysAlaValArgGlnPheLeuLeuHis
AACCAGCAACACAGAGCAGCATCAGTAATACAGAAAGCAGTGCGCCAATTTCTTCTTCAC
LysLysGlnGluLysPheThrSerGlyIleIleLysIleGln >>>> Target Intr
|||||||||||||||||| ||||||||| ||||||||| 467 bp
LysLysGlnGluLysPheAsnSerGlyIleThrLysIleGln++
AAAAAACAGGAAAAATTTAATAGTGGAATAACTAAAATTCAGgt
on 23 >>>> AlaLeuTrpArgGlyTyrSerTrpArgLysLysAsnAspCysThrLys
||||||||||||||||||||||||||||||||| ||||||||||||
++AlaLeuTrpArgGlyTyrSerTrpArgLysLysHisAspCysThrLys
agGCATTGTGGAGAGGCTACTCTTGGAGGAAGAAACATGACTGTACAAAA
IleLysAlaIleArgLeuSerLeuGlnValValAsnArgGluIleArgGluGluAsnLys
||||||||||||||||||||||||||| ||||||||||||||| |||||| |||
IleLysAlaIleArgLeuSerLeuGlnLeuValAsnArgGluIleGlnGluGluAspLys
ATTAAAGCTATACGACTAAGTCTTCAACTTGTTAATAGGGAGATTCAAGAAGAAGACAAG
LeuTyrLysArgThrAlaLeuAlaLeuHisTyrLeuLeuThrTyrLysHisLeuSerAla
|||||||||||||||||||||||||||||| |||||||||||||||||||||||||||
LeuTyrLysArgThrAlaLeuAlaLeuHisSerLeuLeuThrTyrLysHisLeuSerAla
CTCTACAAAAGAACCGCACTCGCACTTCATTCCCTGTTGACGTACAAGCACCTTTCTGCC
IleLeuGluAlaLeuLysHisLeu{G} >>>> Target Intron 24 >>>> {lu
||||||||||||||||||||||||{|} 144 bp {||
IleLeuGluAlaLeuLysHisLeu{G}++ ++{lu
ATTCTGGAAGCTTTAAAACACCTA{G}gt ag{AG
}ValValThrArgLeuSerProLeuCysCysGluAsnMetAlaGlnSerGlyAlaIleSe
}|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
}ValValThrArgLeuSerProLeuCysCysGluAsnMetAlaGlnSerGlyAlaIleSe
}GTGGTAACTAGATTGTCTCCTCTTTGTTGTGAGAACATGGCCCAGAGTGGAGCGATTTC
rLysIlePheValLeuIleArgSerCysAsnArgSerIleProCysMetGluValIleAr
||||||||||||||||||||||||||||||||||||| ||||||||||||||||||||
rLysIlePheValLeuIleArgSerCysAsnArgSerValProCysMetGluValIleAr
TAAAATATTTGTTTTGATCCGAAGTTGTAATCGTAGTGTTCCTTGTATGGAAGTCATCAG
gTyrAlaValGlnValLeuLeuAsnValSerLys >>>> Target Intron 25 >>
|||||||||||||||||||||||||||| ||| 1608 bp
gTyrAlaValGlnValLeuLeuAsnValAlaLys++
ATATGCTGTTCAAGTCTTGCTTAATGTAGCTAAGgt
>> TyrGluLysThrThrSerAlaValTyrAspValGluAsnCysIleAspIleLeuLe
|||||||||||||||||||||||||||||| ||||||||||||||| |||||
++TyrGluLysThrThrSerAlaValTyrAspAlaGluAsnCysIleAspThrLeuLe
agTACGAGAAAACCACTTCAGCAGTTTATGATGCAGAAAATTGCATAGATACACTATT
uGluLeuLeuGlnIleTyrArgGluLysProGlyAsnLysValAlaAspLysGlyGlySe
|||||||||||||||||||||||||||||||||| |||||||||||||||||||||||
uGluLeuLeuGlnIleTyrArgGluLysProGlyAspLysValAlaAspLysGlyGlySe
GGAGCTTCTGCAGATATATCGAGAAAAGCCTGGTGACAAAGTCGCAGACAAGGGTGGAAG
rIlePheThrLysThrCysCysLeuLeuAlaIleLeuLeuLysThrThrAsnArgAlaSe
||||||||||||||||||||||||| ||| |||||| |||||||||||||||||
rIlePheThrLysThrCysCysLeuPheAlaValLeuLeuThrThrThrAsnArgAlaSe
CATTTTTACAAAAACTTGTTGTTTGTTTGCTGTTTTATTGACAACAACGAATCGAGCCTC
r >>>> Target Intron 26 >>>> AspValArgSerArgSerLysValValAs
| 1203 bp |||||||||||||||||||||||| ||
r++ ++AspValArgSerArgSerLysValIleAs
Tgt agGATGTACGAAGCAGGTCCAAAGTTATTGA
pArgIleTyrSerLeuTyrLysLeuThrAlaHisLysHisLysMetAsnThrGluArgIl
||||||||||||||||||||||||||||||| ||||||||| ||||||||||||||
pArgIleTyrSerLeuTyrLysLeuThrAlaArgLysHisLysIleAsnThrGluArgIl
CCGTATTTATAGTCTCTATAAGCTTACAGCACGTAAACATAAAATTAATACTGAAAGAAT
eLeuTyrLysGlnLysLysAsnSerSerIleSerIleProPheIleProGluThrProVa
| |||||||||||||||||| ||| |||||||||||||||||||||||||||||
eThrTyrLysGlnLysLysAsnProSerLeuSerIleProPheIleProGluThrProVa
AACTTATAAACAAAAGAAGAATCCTTCTCTAAGTATTCCCTTTATTCCAGAAACACCTGT
lArgThrArgIleValSer{Ar} >>>> Target Intron 27 >>>> {g}LeuL
|||||||||||||||||||{||} 3000 bp {|}||||
lArgThrArgIleValSer{Ar}++ ++{g}LeuL
AAGGACCAGAATAGTTTCA{AG}gt ag{A}CTTA
ysProAspTrpValLeuArgArgAspAsnMetGluGluIleThrAsnProLeuGlnAlaI
||||||||||| ||| |||||| ||||||||||||||||||||||||||||
ysProAspTrpIleLeuLysArgAspLysLeuGluGluIleThrAsnProLeuGlnAlaI
AACCTGATTGGATTTTGAAAAGAGATAAGCTAGAAGAAATAACGAATCCCCTTCAAGCTA
leGlnMetValMetAspThrLeuGlyIleProTyr
|||||||||||||||||||||||||||||||||||
leGlnMetValMetAspThrLeuGlyIleProTyr
TTCAGATGGTGATGGATACCCTTGGCATTCCCTAT
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