Basic information
Official Symbol ARMCX4
Descriptionarmadillo repeat containing, X-linked 4
Other AliasesLL0XNC01-209G1.1, CXorf35
Other Descriptionarmadillo repeat containing, X-linked 4 pseudogene; armadillo repeat-containing X-linked protein 4
Mutation typeInsert and frame-shift 101-102:R-G^AG
LocationScaffold148073_2:81696 90003 +

  ±  bp flank
WikiWikipedia GeneCard
Sequence
ARMCX4
ATGTCTGCTGCAGGGTTTGAGATCACTGGAAGCAAAGAAACAAGGATACA
TCTGTCTGTATTGCCTGTCTCTAGGTGCAAAGATCTCATGAGTTTATATA
TCTATCTTAGGGTGTATCGCCAAGCACGAGAAATAAAGAGGAGGGAATTG
CCTCGAACCATTGCAGGTCCACCTCCAGTGGCAGCTGTAGTGGCCTTTGA
GTGGCTGAAGACCAGCGCCCTCACAGGCCTACACCCAGACCTACCACCCT
TTTTTCTTAGCCCGAGTGAGCCTCCCCAGTACCTTGTTGGTGACTTCAGC
GGTGATTACATGGGCCGCATTCAGGAAGTGGGCTGGGCGACTGCAGGACT
GATGATCTGGGCTGGCACCTGCTACTACATTTACAAATTAACCAAGGGAA
GAGCCCAAAGTGTGAGGAGACTTTCCAGACATGAGTCCAGTGTCGCAATG
GAGACTGTGGTTGGGGTACAGAACCAGGCCTTGGCCATGAGTGAAGCCAT
GGCTGGGGCTAAGATTGAGACTAGACCCAAGGCCAAGACTGGAGCAGAAA
CTGGAGCAGGATGTGGGCCTGGGGCTGAAGTAGAAACCAAAGCCATTGCT
ATAGCCAGACCCAAAACCAACACTCAGGCCAACACAATAGCTGAGGTAGA
GGTAGAGACCCAATCTGAGGCCAAAGCAGTGTCTGGAACACTGGTCATGA
CAGAAGCAGTGTCCAGTAGCCAGTGGACTGAAGCCAAGGCCGAAGCCAAG
GTCAAAGCCAGGGAAGTGGCTGTGAAAGAGGCAGTGACCCAAACTGATGC
TGAGGCTGGGAAAATAGTCAAAAAGGAGGCAGTGACTCAGACCAAGGCTA
AAACTTGGGCACTGATTGCCAGGGCAGAGACCAAGAAGGAAGCAATGACC
CAGACCAAAGCTGAAGTTCATGTATCGACTGAAAAAGAGGCAAAGATTAA
CAAAGTAGTGGTGGCACAGAGTGAGGCGCTGGCAGTGACCAGAGAAGTGG
TCAAGATGGGGACCATGATCAAGACTGAAACTGTGGCTGAGGACAAGGCA
AGAACCCTGGAAGAGACTGTGAGTGTGGCTAAGACTCAGTCTGAGGCCAG
GCCTGGTGTCACAATTGATGCTAGGGGAAATTCCAATGGCATGTCCAGGG
CAGTGGCTGGAGTGGACATGACGTCCTGTGCACAGTCTCAGGCTGTGGCC
AAGAGCCAGGGTGATAAAATGCCTGGTACTAGGGTTGAGGACAAGGGGAA
TCGCAAAACCATGTCTAAGGCAAGGTCTGGAGCAAATGTGAGGGCTTCTG
CTCAGTCTCAACTTGCTGCCAAGGCCCATGCTGAGGCCATGCTTGGGGCA
AAGATTGATGCTGGGGGTAATACCAATGCCATGTGTAAGACAGGGGCAGA
TATGAGAACTGGTATACAATCTCAGACTGAGGCCAAGAAACAGGCTGAGG
TAATATCTGGTGCCAGAGTTGATGGCAAGGGAAATATCAATGCCATATCC
AAGGCAATGACTGAAGCTGATGTGAGAGCTGCTGCTCAGCCTCAAGCTGT
AGTCAGTGCTCAGGCTGAGGTCATGCCTGATGCCAAGGTTAAAGGCAGAG
GCAATCCCAATGCTGTGGCTAAAGCAGGGGCCAGGACAAACTCGAGAGCT
GGTTCCCAAGCTGAAGCCTTGCCTGATGTCAGGGATAAGACCAAAGACAA
TCCCAGTGTCACGGCCAAGACAGGGCCTGGGACAGATACATTGTCTTATA
CACAGCCTCAGCCTGTGTCCAATGTCCAGGCTGATGCCTTGCCTGGTGGC
AGAATTAAAGCTAAGGGAAATGCCAGCATCATGTCTAAGGAAGGAACTGG
GACAGACACAAAAGCACAGTCTCCTGTTGTGACCCAGAGCCAGGGTGAAG
CCTTACCCAGTACTAGAAGTAAGGGTAGGGGCAAAACCAAAGCCAAGTCT
AAGGCAGGGATTGGGATAGATATGAAAACCTGTGCACGACCTCAGGCTGG
GACCAAGACACAATCTGAGGCCTTGCCTGATTCCAGGGTTGATGGTAAGG
GCTATCTTAATGCTATTTCTAGAGCTGATGCTAAGGCAGACCAGAAAGCC
TGTGGTCAGCCCCAGACTGTGGCGAATTCCCAGGGTGAGGGCTCAGCTGG
TGCCAAGAAGAAAGTCAAGGGTAATCCCAATGCTGTGTCTAAGACAGGGG
TTGGGGAAAATACAACAGGCTCTGTCCAGCCTCAGATTGTGGCCAATCCC
CAGGGTGAGGCCTTGCCCGGTGCCAAAAAGAAAGTCAAGGGTAATCCCAA
TGCTGTGTCTAAGACAGGGGTTGGGGAAAATACAACAGGCTCTGCCCAGC
CTCAGGTTGTGGCCAGTCCCCAGGGTGAGGCCTTGCCTGGTACCAAGAAT
AAAGTCAAGGGTAATCCTAATGCTGTGTCTAAGGCAGAGGCTGGGGCAGG
TACTGTAAGCTCTGCCCAGCCCCAGGTTGTGGCCAATTCTCAGGGTGAGG
CCTTGCCCGGTGCCAAGAAAAAAGTCAAGGGTAATCCTAATTCTGTGTCT
AAGGCAGAGGCTGGGGCAGGTACTGTAAGCTCTGCCCAGCCCCAGGTTGT
GGCCAATTCTCAGGGTGAGGCCTTGCCCGGTGCCAAGAAAAAAGTCAAGG
GTAATCCTAATGCTGTGCCTAAGGCAGGGGCTGGCACTGATATAGTGGGT
CCTACCCAGTCCCAGGATATGGTTAGTTCCCAGGGTGAGGTATTGCCTAG
TGCCAAAAACAAGGTCAGGGGTAATCGCAATGCTGTGCCTAAGGCAGGGG
ACAGGACAGATACAGTGGGCTCTGCCCAGCCCCTAGATATATCCAGGTCC
CAGGATGAGGTCTTGCCTGGTGCCAAGAATAAGGTCAAGGGAAGTCCCAG
TGCTGTGCCTAAAGCAGAAGCTGGGTCAAGTACAGTGGGCTCTGCCCAGT
CTCAGCCTACGGCCAGTTTCCAGGGTAAGGCCTTGCCTGGTGCCAAGAAT
AAGATCAGGAGCAATTCCAATGCCATGTCTAAAGCAGGGGTTGGGACAGA
TACAGTGGGCTCTGCTCAGCCCCAGACTGTGACCAGTTCCCAGAATGAGG
CCTTGTTTGGTACCAAGAATAAGGTCAAGAGCAATACCAATACTGTGTCT
AAGGCAGAGGCTGGGGCAGGTACAATGGGCTCTGCCAAGTCCCAGACTGT
GACCACTTCCCAAAGTGAAACCTTGCTTGGTGCCCGGAATAAGGTCAAGG
GTAATTCTAATATTGTGTCTAAAGCAGAGGCTGGGGCAGGTACATTGAGC
TCTATCCAGAGCCAGGCTGTGGATAGTTTCCTGGGGGAGAACTTGCTTGG
TGCCAGGAATAAGGTCAGAGGCAATGCTAATGCTGCTCCTAAAACAGGGG
CTGGGGCAAATAGAAGGGGCTCTACCCAGCCCCAAACTGTGGGAAGTTCC
CAGGGTGAAGTCTTGCCTAGGGCAAGGGACAAAGCTATGCCTAGTTCTGA
GGTGGAAGCCACAACAGAAGGTGAGGTCTATCCAAAGCGAGAAGCTCTGG
CAGTGTCCACTTCTGAGAGTGAGGGTGTGACAGGTGCTGAGGCCTCTAGA
AAGACTCAGACTGATATCCATGACTACTACTGGAATGGAATTGGTGTTGA
AGATTGGATTGCTGCTGAGCGGTGGATCAAATTTAGGTTTCAGGCCATGG
ATGGAGATTGGGAGAATAATATGTCTTGGGCTGATGATGAGAATGAAATT
AATGTTGGGGCCTGGAGTGGGTCTTCTGACAAGGCTGGTATTATTAGGTC
CTGGACTATGGCTTTTTCTGGGGCCAGCATTAAGTCCTGGACTGGGAATG
AGGTTGCTCTTGGGTCCTGGGCTGGACCTGGGGACCAGGCCTGTGGAGGA
CTCTGGGCTGGGGGTCAGGCTAGTGAGGGGTCCTGGGCTGGGGACAAGGC
CAGTGGGGGTTCTTGGACTGGGATTGAGAACCAGGACAGTGGTGGGTCTT
GGGCTTCTGGAAACCAGGCCATTGGAGGGCCCTGGGCTGGGGGTCAGGCC
AGTGAAGGGTCTTGGCCTGGGGGCCAGACCAGTGGGATCTCCTGGGCTGG
GGAAGAGGCTATTGGAGGGTCTTGGACTGGGAACCAGGACAGTGGAGGAT
CTTGGGCTGGGACTGGGGCTGGGAATATGGGTACTATTGGGTACTGGACT
GGGGGTGTGGATCAGGCTAGTGGTGGGTCCTGGGCTGGGACTGATCATCA
ATCTGGGGGTGGGTCCAAGCCTGTATTTATGGATCAGGCTAATGAAAAAG
AATCTTGGGCTGGGACTGGTGGCCAGGCCAGTGAAGGGTCCAGGTTGGGT
CCTGAGAACCAGTCTAGTGGAAGGTCTTGGGCTGGGACTGTGGACCGAGT
CAGTGGAGGGTCTAGGCTGGGGCTTGTAGACCAGTCCAGTGGAAGTCCCT
GGGCTGACACTGAGGACCAGGCTGGTGGAGGGTCTAAGCCAGGGTCCATG
GACCAACCAGGTGGAGAGCCCTGGGCTGGGACAGGTAACCAGTCTAGTGG
TGGATCTAAACCTAGATTTGAGAATCAGGCCAGTGAAGAAGGGTCCTGGA
CTGGAGCTGTTTGCCAGAGTGGTGGTGGGTCCAAGTCTGGACCCGAGGAC
CAGTCCAGTGGAACATCCTGGGGTGACTCCAGGAACCAAATCAGTGGAGG
ATTCTTGATTGGGGCTGTGAATCAGGCCAGTGGAGATTCCTGGGTTGCTA
CTGGGGACCAGGCCAGTGGATGGTTTTGTGTTTACACTGGGAGTCAGGCT
AGTGGAGGAGGTTCTTGGGTTGGTGCTGGTGGCCAGGATGTTGGAGAGTC
TAGGCTGGAGTTCACAAACCAGTCCGGTAGTGGGTCTTGGGCAGGCACTG
GGAATCAGGTCAGTGGAGGGTCCTGGACTGGGACTGGGGATCAAGCTGGT
GGGTGTTCCAAACCTGGATTTGAGGATCAGACCATTGGAGGAGGGTTCTG
GTCTAGTGCTGGGGATCAGGCCAGTGGAGGGTCTAGTCTGGGGCCTGAAG
ATCAGCCCAGTGGAGGAGGTTCCTGGGATGGGATTTGTGGCCAGGTCATT
GGAGAATCAAGGCCAGAGCCTGCAGACAAGTCCAGTGGTGGGACCTGGGC
TGGCACTGCCAGTCAGGCCAGTGGAAGGTCCTGGGTTGGGCCTGGGGATC
AGGTTGATGGCTGTCCCAAATCTGGATTTGAAGACCAGGCCTGTGGAGGA
AGCTCCTGGGCTGGTGTTGGGAACCAAGCCAGTGGAGAATCTTGGACTGG
CTCTAGGCCTGTGAATGAAGTCAGTGGAGAATCTGGATTGGAGCCTGAGG
ATCAAGCCAGTGGAGGGTCCTGGGCTAGGTCTGAGGACCAGACCAGTGGA
AGGTTTCAGGTCACTGCTGAGACAGAGGCCAATGAAGGATTCTGGTTTGG
GCCTGGGAGTGAAGCCTGTATAGGGACTTGGTGCTGGACAGGGGAAAAGG
CTGTTATTATGCCCAGTTCTCATGCCAAGGATGAGGCCAGTACTGAATCC
AGATCAGGGGCTGAAGAGGAGGTCATCACAAATTCTAGTGTTGGGGCTGA
GAATAAGACTAGTGTTGGGTCCTGGATTGGATCTGAGGAGGCAGCTTACA
TGGGTTCCTGTCGGGGGGCTGAGGGTGGGGCTGAGGCTGGGTCTGAAGCG
AGAATGGGGTCTTGGTCCTGGAACGGAGATACAACCACTATAGAGTCTAG
GCTTGGGGCTGGGGAAGAGGCTGGCATAGAGTCCTGGACTTTGGCTAGGG
ATGTAGATGAGGATGAGCTAAGCAGAACGTCCAGCCCTGATATTGAGGAG
ATCAGTTTAAGGTCTTTGTTTTGGGCTGAGAGTGAGAATAACAATGAATT
CAGATCCAAGAGTGGGAAAGATGTCCATTTTGAGTCTGGGGCTGGAGAAA
AGGCCAGCATCCAGGATAAGTTTGAGGCTGCTGGTGGAGTTGATATAAGA
TCTTGGTTCTGTGCTGAAAGTGAAAACAGAAGTGAGGACAAATCTGCACC
TAAGACTAAAGCCAAAAAGTCAGCTGAGTCAAGAGGCACATACCCATCCA
TGGTCCCCGGGGCAGGAATGGGGTCATGGGATGGAGCCATGATCTGGTCA
GAAACAAAGTTTCCACACCAAAGTGACGCCAGCTACCCAGTTGAAGATGA
GTTCAGAAAGCAGGTCAGGACTGGGGAGAAAATTCGGCCCGGGTCCTGCC
GCTGTAAACGTGATGCTAATATGGATCCACGAGAGCTTGAAAAACTCATT
TGCATGATTGAGATGACTGAAGATCCTTCTGTTCATGAAATAGCCAATAA
TGCTCTATATAACAGTGCTGATTATCCTTATTCCCACGAAGTTGTTCGTA
ATGTAGGTGGAATCTCAGTTATTGAAAGCTTACTCAATAATCCCCACCCC
AGTGTTAGGCAGAAGGCTTTAAATGCATTGAATAATATCTCAGTTGCTGC
TGAAAACCATAGGAAGGTTAAAACATATTTAAATCAAGTCTGTGAAGACA
CAGTCACCTATCCCTTGAATTCAAATGTGCAGCTGGCTGGACTAAGATTG
ATAAGGCATCTGACTATTACTAGTGAATATCAGCATATGGTTACAAACTA
TATCTCAGAATTTCTTCGTTTGTTAACTGTGGGAAGTGGAGAAACTAAAG
ACCATGTTTTGGGAATGCTCTTGAATTTCTCAAAAAATCCATCTATGACA
AAAGACTTGCTCATTGCTAATGCTCCAACAACACTAATGAATATTTTTAG
CAAGAAAGAGACAAAAGAGAATATTCTTAATGCTCTTTCGTTATTTGAAA
ATATAAATTACCACTTTAAAAGAAGAGCAAAAGCATTTACTCAGGACAAG
TTTAATAAAAATTCCCTTTATTTCCTATTCCAACGACCTAAAGCATGTGC
CAAGAAACTTCGAGTCTTAGCAGCAGAATGTAATGACCCTGAGGTGAAAG
AAAGAGTTGAGCTATTAATAAGTAAACTC

Alignment
Align speciePep lengthPep align beginPep align endMutaion type and postion
Human239412394Insert and frame-shift 101-102:R-G^AG
 Instructions:
 *** -> premature termination codon;  # -> frame shift 

 Alignment:
 Human     pep sequence --->
 ||||||||||||||||||||||
 Treeshrew pep sequence --->
 Treeshrew cds sequence --->
  
 MetSerAlaAlaGlyLeuLysIleThrGlySerLysGluThrLysArg  >>>> Targe
 |||||||||||||||      |||||||||||||||||||||                  
 MetSerAlaAlaGlyPheGluIleThrGlySerLysGluThrArgIle-+          
 ATGTCTGCTGCAGGGTTTGAGATCACTGGAAGCAAAGAAACAAGGATAtt          

 t Intron 1 >>>>  ArgLeuLeuLeuIleSerIleAspTrpSerArgAspLeuMetA
 306 bp              |||                           ||||||||| 
                +-HisLeuSerValLeuProValSerArgCysLysAspLeuMetS
                acCATCTGTCTGTATTGCCTGTCTCTAGGTGCAAAGATCTCATGA

 snLeuCysIleTyrPheArgValTyrCysGlnGluLysGlnGluGluArgArgGluLeuP
   |||   ||||||   |||||||||   |||               |||||||||||||
 erLeuTyrIleTyrLeuArgValTyrArgGlnAlaArgGluIleLysArgArgGluLeuP
 GTTTATATATCTATCTTAGGGTGTATCGCCAAGCACGAGAAATAAAGAGGAGGGAATTGC

 roArgIleIleThr{G}  >>>> Target Intron 2 >>>>  {ly}ProProProG
 |||||   |||   {|}            341 bp           {||}||||||||| 
 roArgThrIleAla{G}++                         ++{ly}ProProProV
 CTCGAACCATTGCA{G}gt                         ag{GT}CCACCTCCAG

 luAlaAlaValValAlaPheGluTrpLeuLysThrSerThrLeuThrGlyLeuHisProG
   ||||||||||||||||||||||||||||||||||||   |||||||||||||||||| 
 alAlaAlaValValAlaPheGluTrpLeuLysThrSerAlaLeuThrGlyLeuHisProA
 TGGCAGCTGTAGTGGCCTTTGAGTGGCTGAAGACCAGCGCCCTCACAGGCCTACACCCAG

 lnLeuProLeuSerLeuProGlnProGluCysAlaLeuProTyrLeuValArgAlaPheS
   ||||||               |||               |||||||||      ||||
 spLeuProProPhePheLeuSerProSerGluProProGlnTyrLeuValGlyAspPheS
 ACCTACCACCCTTTTTTCTTAGCCCGAGTGAGCCTCCCCAGTACCTTGTTGGTGACTTCA

 erArg--GlyAspTyrMetGlyArgIleGlnGluValGlyTrpValThrAlaGlyLeuVa
 ||   ##||||||||||||||||||||||||||||||||||||   ||||||||||||  
 er---##GlyAspTyrMetGlyArgIleGlnGluValGlyTrpAlaThrAlaGlyLeuMe
 GC---AGGGTGATTACATGGGCCGCATTCAGGAAGTGGGCTGGGCGACTGCAGGACTGAT

 lIleTrpAlaGlyThrCysTyrTyrIleTyrLysPheThrLysGlyArgAlaGlnSerVa
  |||||||||||||||||||||||||||||||||   |||||||||||||||||||||||
 tIleTrpAlaGlyThrCysTyrTyrIleTyrLysLeuThrLysGlyArgAlaGlnSerVa
 GATCTGGGCTGGCACCTGCTACTACATTTACAAATTAACCAAGGGAAGAGCCCAAAGTGT

 lArgThrLeuAlaArgAsnGlySerThrValLysMetGluThrValValGlyValGlnSe
 ||||   |||   |||      |||   |||   ||||||||||||||||||||||||  
 lArgArgLeuSerArgHisGluSerSerValAlaMetGluThrValValGlyValGlnAs
 GAGGAGACTTTCCAGACATGAGTCCAGTGTCGCAATGGAGACTGTGGTTGGGGTACAGAA

 rGlnThrLeuAlaIleAsnGlu<-><-><-><->AlaGluIleLysThrLysProGlnVa
  |||   ||||||      |||            |||   |||   |||   |||     
 nGlnAlaLeuAlaMetSerGluAlaMetAlaGlyAlaLysIleGluThrArgProLysAl
 CCAGGCCTTGGCCATGAGTGAAGCCATGGCTGGGGCTAAGATTGAGACTAGACCCAAGGC

 lGluIleGlyAlaGluThrGlyAlaArgSerGlyProArgAlaGluValGluThrLysAl
        ||||||||||||||||||      ||||||   ||||||||||||||||||||
 aLysThrGlyAlaGluThrGlyAlaGlyCysGlyProGlyAlaGluValGluThrLysAl
 CAAGACTGGAGCAGAAACTGGAGCAGGATGTGGGCCTGGGGCTGAAGTAGAAACCAAAGC

 aThrAlaIleAlaIleHisArgAlaAsnSerGlnAlaLysAlaMetValGlyAlaGluPr
 |   |||||||||            |||   ||||||                  |||  
 aIleAlaIleAlaArgProLysThrAsnThrGlnAlaAsnThrIleAlaGluValGluVa
 CATTGCTATAGCCAGACCCAAAACCAACACTCAGGCCAACACAATAGCTGAGGTAGAGGT

 oGluThrGlnSerGluSerLysValValAlaGlyThrLeuValMetThrGluAlaValTh
  |||||||||||||||   |||   |||   |||||||||||||||||||||||||||  
 lGluThrGlnSerGluAlaLysAlaValSerGlyThrLeuValMetThrGluAlaValSe
 AGAGACCCAATCTGAGGCCAAAGCAGTGTCTGGAACACTGGTCATGACAGAAGCAGTGTC

 rLeuThr<-><-><-><-><-><-><->GluValLysAlaLysAlaArgGluValAlaMe
                             |||   |||   ||||||||||||||||||  
 rSerSerGlnTrpThrGluAlaLysAlaGluAlaLysValLysAlaArgGluValAlaVa
 CAGTAGCCAGTGGACTGAAGCCAAGGCCGAAGCCAAGGTCAAAGCCAGGGAAGTGGCTGT

 tLysGluAlaValThrGlnThrAspAlaGluAlaGlyLysIleValLysLysGluAlaVa
  |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 lLysGluAlaValThrGlnThrAspAlaGluAlaGlyLysIleValLysLysGluAlaVa
 GAAAGAGGCAGTGACCCAAACTGATGCTGAGGCTGGGAAAATAGTCAAAAAGGAGGCAGT

 lThrGlnThrLysAlaLysAlaTrpAlaLeuValAlaLysThrGluAlaLysArgGluAl
 |||||||||||||||||||   |||||||||   |||      |||   |||   |||||
 lThrGlnThrLysAlaLysThrTrpAlaLeuIleAlaArgAlaGluThrLysLysGluAl
 GACTCAGACCAAGGCTAAAACTTGGGCACTGATTGCCAGGGCAGAGACCAAGAAGGAAGC

 aMetThrGlnThrLysAlaGluThrHisIleLeuAlaGluLysGluThrGluIleAsnAr
 ||||||||||||||||||||||   |||         |||||||||      ||||||  
 aMetThrGlnThrLysAlaGluValHisValSerThrGluLysGluAlaLysIleAsnLy
 AATGACCCAGACCAAAGCTGAAGTTCATGTATCGACTGAAAAAGAGGCAAAGATTAACAA

 gValMetValThrGlnSerGluThrLeuAlaValProArgGluValAlaLysMetGlyAl
  |||   |||   |||||||||   |||||||||   |||||||||   |||||||||  
 sValValValAlaGlnSerGluAlaLeuAlaValThrArgGluValValLysMetGlyTh
 AGTAGTGGTGGCACAGAGTGAGGCGCTGGCAGTGACCAGAGAAGTGGTCAAGATGGGGAC

 aThrAsnLysThrGlyIleValAspGluThrLysThrArgAlaLeuGluGluThrValSe
        ||||||      |||   |||   |||   |||   |||||||||||||||||
 rMetIleLysThrGluThrValAlaGluAspLysAlaArgThrLeuGluGluThrValSe
 CATGATCAAGACTGAAACTGTGGCTGAGGACAAGGCAAGAACCCTGGAAGAGACTGTGAG

 rValAlaLysThrGlnSerGluAlaArgProGlyAlaThrValAspAlaArgGlyAsnPr
 ||||||||||||||||||||||||||||||||||   |||   |||||||||||||||  
 rValAlaLysThrGlnSerGluAlaArgProGlyValThrIleAspAlaArgGlyAsnSe
 TGTGGCTAAGACTCAGTCTGAGGCCAGGCCTGGTGTCACAATTGATGCTAGGGGAAATTC

 oAsnGlyMetSerArgGluValAlaGlyValAspMetLysSerCysAlaGlnSerGlnAl
  |||||||||||||||   ||||||||||||||||||   ||||||||||||||||||||
 rAsnGlyMetSerArgAlaValAlaGlyValAspMetThrSerCysAlaGlnSerGlnAl
 CAATGGCATGTCCAGGGCAGTGGCTGGAGTGGACATGACGTCCTGTGCACAGTCTCAGGC

 aValThrLysIleGlnGlyAspAspMetProGlyThrGlyValGluAspMetGlyAsnCy
 ||||   |||   |||||||||   ||||||||||||   |||||||||   ||||||  
 aValAlaLysSerGlnGlyAspLysMetProGlyThrArgValGluAspLysGlyAsnAr
 TGTGGCCAAGAGCCAGGGTGATAAAATGCCTGGTACTAGGGTTGAGGACAAGGGGAATCG

 sLysThrMetSerArgAlaGluSerGlyAlaAspThrArgAlaSerAlaGlnProGlnIl
  ||||||||||||   |||   |||||||||      |||||||||||||||   |||  
 gLysThrMetSerLysAlaArgSerGlyAlaAsnValArgAlaSerAlaGlnSerGlnLe
 CAAAACCATGTCTAAGGCAAGGTCTGGAGCAAATGTGAGGGCTTCTGCTCAGTCTCAACT

 ePheAlaLysThrGlnThrGluAlaIleProGlyAlaLysIleAspAlaGlyGlyAsnTh
     ||||||         ||||||      |||||||||||||||||||||||||||||
 uAlaAlaLysAlaHisAlaGluAlaMetLeuGlyAlaLysIleAspAlaGlyGlyAsnTh
 TGCTGCCAAGGCCCATGCTGAGGCCATGCTTGGGGCAAAGATTGATGCTGGGGGTAATAC

 rAsnAlaMetCysLysValGlyAlaGlyAlaAspValArgAlaCysIleGlnProGlnTh
 ||||||||||||||||         |||||||||   |||      ||||||   |||||
 rAsnAlaMetCysLys------ThrGlyAlaAspMetArgThrGlyIleGlnSerGlnTh
 CAATGCCATGTGTAAG------ACAGGGGCAGATATGAGAACTGGTATACAATCTCAGAC

 rValAlaLysLysGlnAlaGluValThrSerGlyAlaArgValAspGlyArgGlyAsnTh
 |   |||||||||||||||||||||   |||||||||||||||||||||   ||||||  
 rGluAlaLysLysGlnAlaGluValIleSerGlyAlaArgValAspGlyLysGlyAsnIl
 TGAGGCCAAGAAACAGGCTGAGGTAATATCTGGTGCCAGAGTTGATGGCAAGGGAAATAT

 rAsnValIleSerLysAlaIleThrGlyAlaAspMetArgAlaAlaAlaGlnProGlnAl
  |||   ||||||||||||   |||   ||||||   |||||||||||||||||||||||
 eAsnAlaIleSerLysAlaMetThrGluAlaAspValArgAlaAlaAlaGlnProGlnAl
 CAATGCCATATCCAAGGCAATGACTGAAGCTGATGTGAGAGCTGCTGCTCAGCCTCAAGC

 aValAlaSerThrHisAlaGluAlaMetSerAspAlaLysValLysAsnArgGlyAsnPr
 ||||   |||      ||||||   |||   |||||||||||||||   |||||||||||
 aValValSerAlaGlnAlaGluValMetProAspAlaLysValLysGlyArgGlyAsnPr
 TGTAGTCAGTGCTCAGGCTGAGGTCATGCCTGATGCCAAGGTTAAAGGCAGAGGCAATCC

 oAsnAlaMetThrLysAlaGlyAlaLysAlaAsnLeuArgAlaAsnSerGlnValGluAl
 |||||||      ||||||||||||      |||   ||||||   ||||||   |||||
 oAsnAlaValAlaLysAlaGlyAlaArgThrAsnSerArgAlaGlySerGlnAlaGluAl
 CAATGCTGTGGCTAAAGCAGGGGCCAGGACAAACTCGAGAGCTGGTTCCCAAGCTGAAGC

 aLeuProAspAlaArgAspLysSerArgGlyAsnProAsnValMetAlaLysValGlyAs
 ||||||||||   |||||||||         ||||||   |||   ||||||   |||  
 aLeuProAspValArgAspLysThrLysAspAsnProSerValThrAlaLysThrGlyPr
 CTTGCCTGATGTCAGGGATAAGACCAAAGACAATCCCAGTGTCACGGCCAAGACAGGGCC

 pGlyThrAspMetLeuSerCysThrGlnProGlnLeuValAlaSerValGlnAlaAspTh
  |||||||||   ||||||   ||||||||||||   |||      ||||||||||||  
 oGlyThrAspThrLeuSerTyrThrGlnProGlnProValSerAsnValGlnAlaAspAl
 TGGGACAGATACATTGTCTTATACACAGCCTCAGCCTGTGTCCAATGTCCAGGCTGATGC

 rLeuSerAspGlyLysIleLysValArgGlyAsnValAsnThrMetProLysGluGlyAl
  |||      |||   ||||||      ||||||         |||   |||||||||  
 aLeuProGlyGlyArgIleLysAlaLysGlyAsnAlaSerIleMetSerLysGluGlyTh
 CTTGCCTGGTGGCAGAATTAAAGCTAAGGGAAATGCCAGCATCATGTCTAAGGAAGGAAC

 aGlyValAspMetLysAlaGlnGly<-><->MetAlaGlnSerGlnGlyGluAlaLeuPr
  |||   |||   |||||||||               |||||||||||||||||||||||
 rGlyThrAspThrLysAlaGlnSerProValValThrGlnSerGlnGlyGluAlaLeuPr
 TGGGACAGACACAAAAGCACAGTCTCCTGTTGTGACCCAGAGCCAGGGTGAAGCCTTACC

 oAsnThrArgGlyLysAlaArgGlyLysAlaLysAlaLysCysLysThrGlyProGlyMe
 |   ||||||   |||   |||||||||   |||||||||   |||   |||   |||  
 oSerThrArgSerLysGlyArgGlyLysThrLysAlaLysSerLysAlaGlyIleGlyIl
 CAGTACTAGAAGTAAGGGTAGGGGCAAAACCAAAGCCAAGTCTAAGGCAGGGATTGGGAT

 tAspMetLysThrCysThrGlnProGlnAlaGlyValLysThrProAlaGluAlaLeuLe
  |||||||||||||||      ||||||||||||   ||||||      |||||||||  
 eAspMetLysThrCysAlaArgProGlnAlaGlyThrLysThrGlnSerGluAlaLeuPr
 AGATATGAAAACCTGTGCACGACCTCAGGCTGGGACCAAGACACAATCTGAGGCCTTGCC

 uAspSerArgValAspGlyArgGlyAsnProAsnAlaThrSerLysAlaGlyThrLysAl
  ||||||||||||||||||   |||      ||||||   |||   |||      |||||
 oAspSerArgValAspGlyLysGlyTyrLeuAsnAlaIleSerArgAlaAspAlaLysAl
 TGATTCCAGGGTTGATGGTAAGGGCTATCTTAATGCTATTTCTAGAGCTGATGCTAAGGC

 aAspGlnArgValCysGlyGlnProLeuValValAlaAsnProGlnGlyGluAlaLeuPr
 |||||||      ||||||||||||      |||||||||   |||||||||        
 aAspGlnLysAlaCysGlyGlnProGlnThrValAlaAsnSerGlnGlyGluGlySerAl
 AGACCAGAAAGCCTGTGGTCAGCCCCAGACTGTGGCGAATTCCCAGGGTGAGGGCTCAGC

 oGlyAlaLysAsnLysValLysGlyAsnProHisThrValLeuLysValGlyAlaGlyGl
  |||||||||   ||||||||||||||||||      |||   |||   |||   |||||
 aGlyAlaLysLysLysValLysGlyAsnProAsnAlaValSerLysThrGlyValGlyGl
 TGGTGCCAAGAAGAAAGTCAAGGGTAATCCCAATGCTGTGTCTAAGACAGGGGTTGGGGA

 uGlyThrThrAspSerAlaGlnProGluAlaValValSerPheGlnGlyGluAlaLeuLe
 |   ||||||   |||   ||||||      |||         |||||||||||||||  
 uAsnThrThrGlySerValGlnProGlnIleValAlaAsnProGlnGlyGluAlaLeuPr
 AAATACAACAGGCTCTGTCCAGCCTCAGATTGTGGCCAATCCCCAGGGTGAGGCCTTGCC

 uGlyThrLysAsnLysValLysGlyAsnProAsnValValLeuLysAlaGluValGlyGl
  |||   |||   |||||||||||||||||||||   |||   |||      ||||||||
 oGlyAlaLysLysLysValLysGlyAsnProAsnAlaValSerLysThrGlyValGlyGl
 CGGTGCCAAAAAGAAAGTCAAGGGTAATCCCAATGCTGTGTCTAAGACAGGGGTTGGGGA

 uGlyAlaMetGlyThrAlaGlnLeuGlnIleMetAlaSerSerLysGlyGluAlaLeuLe
 |         |||   ||||||   |||      ||||||      ||||||||||||  
 uAsnThrThrGlySerAlaGlnProGlnValValAlaSerProGlnGlyGluAlaLeuPr
 AAATACAACAGGCTCTGCCCAGCCTCAGGTTGTGGCCAGTCCCCAGGGTGAGGCCTTGCC

 uAspSerLysAsnLysValLysGlyAsnSerAsnAlaValSerLysAlaGlyAlaGlyTh
        |||||||||||||||||||||   ||||||||||||||||||   ||||||  
 oGlyThrLysAsnLysValLysGlyAsnProAsnAlaValSerLysAlaGluAlaGlyAl
 TGGTACCAAGAATAAAGTCAAGGGTAATCCTAATGCTGTGTCTAAGGCAGAGGCTGGGGC

 rAspThrThrGlySerValGlnProGlnIleValAlaAsnSerGlnGlyGluValLeuPr
     |||      |||   |||||||||   |||||||||||||||||||||   |||||
 aGlyThrValSerSerAlaGlnProGlnValValAlaAsnSerGlnGlyGluAlaLeuPr
 AGGTACTGTAAGCTCTGCCCAGCCCCAGGTTGTGGCCAATTCTCAGGGTGAGGCCTTGCC

 oGlyAlaLysAsnLysIleArgGlyAsnProThrThrValProAsnSerGlyValGlyPr
 ||||||||||   |||      |||||||||      |||               |||  
 oGlyAlaLysLysLysValLysGlyAsnProAsnSerValSerLysAlaGluAlaGlyAl
 CGGTGCCAAGAAAAAAGTCAAGGGTAATCCTAATTCTGTGTCTAAGGCAGAGGCTGGGGC

 oTyrThrThrAspSerAlaArgLeuGlnAlaValAlaAsnSerGlnGlyGluValLeuPr
     |||      ||||||      |||   |||||||||||||||||||||   |||||
 aGlyThrValSerSerAlaGlnProGlnValValAlaAsnSerGlnGlyGluAlaLeuPr
 AGGTACTGTAAGCTCTGCCCAGCCCCAGGTTGTGGCCAATTCTCAGGGTGAGGCCTTGCC

 oGlyAlaLysAsnLysValLysAlaAsnLeuAsnAlaValSerLysAlaGluAlaGlyMe
 ||||||||||   |||||||||   |||   |||||||||   ||||||   ||||||  
 oGlyAlaLysLysLysValLysGlyAsnProAsnAlaValProLysAlaGlyAlaGlyTh
 CGGTGCCAAGAAAAAAGTCAAGGGTAATCCTAATGCTGTGCCTAAGGCAGGGGCTGGCAC

 tGlyAlaThrGlySerValGlnProGlnAlaValAlaAsnSerHisCysGluThrLeuPr
           |||      |||   |||            |||      |||   |||||
 rAspIleValGlyProThrGlnSerGlnAspMetValSerSerGlnGlyGluValLeuPr
 TGATATAGTGGGTCCTACCCAGTCCCAGGATATGGTTAGTTCCCAGGGTGAGGTATTGCC

 oGlyAlaLysAsnLysValArgGlyAsnTrpAsnAlaValSerLysAlaGlyAlaGlyMe
 |   ||||||||||||||||||||||||   |||||||||   |||||||||        
 oSerAlaLysAsnLysValArgGlyAsnArgAsnAlaValProLysAlaGlyAspArgTh
 TAGTGCCAAAAACAAGGTCAGGGGTAATCGCAATGCTGTGCCTAAGGCAGGGGACAGGAC

 tAspThrArgGlySerAlaGlnProGlnAlaValAlaAsnSerGlnGlyGluValLeuPr
  ||||||   |||||||||||||||               ||||||   |||||||||||
 rAspThrValGlySerAlaGlnProLeuAspIleSerArgSerGlnAspGluValLeuPr
 AGATACAGTGGGCTCTGCCCAGCCCCTAGATATATCCAGGTCCCAGGATGAGGTCTTGCC

 oGlyAlaLysAsnLysValLysGlyAsnProAsnValValSerLysAlaGlyAlaArgGl
 |||||||||||||||||||||||||   |||      |||   ||||||   |||     
 oGlyAlaLysAsnLysValLysGlySerProSerAlaValProLysAlaGluAlaGlySe
 TGGTGCCAAGAATAAGGTCAAGGGAAGTCCCAGTGCTGTGCCTAAAGCAGAAGCTGGGTC

 uAspThrValGlySerThrGlnProGlnValLeuAlaSerSerGlnArgGluThrLeuPr
     ||||||||||||   |||   |||      ||||||   |||         |||||
 rSerThrValGlySerAlaGlnSerGlnProThrAlaSerPheGlnGlyLysAlaLeuPr
 AAGTACAGTGGGCTCTGCCCAGTCTCAGCCTACGGCCAGTTTCCAGGGTAAGGCCTTGCC

 oGlyAlaArgAsnLysValLysGlyAsnSerAsnValValSerLysAlaGlyAlaArgGl
 |||||||   ||||||         |||||||||      ||||||||||||        
 oGlyAlaLysAsnLysIleArgSerAsnSerAsnAlaMetSerLysAlaGlyValGlyTh
 TGGTGCCAAGAATAAGATCAGGAGCAATTCCAATGCCATGTCTAAAGCAGGGGTTGGGAC

 uAspThrMetGlySerAlaGlnProGlnValValAlaAsnSerGln{A}  >>>> Targ
  ||||||   ||||||||||||||||||   |||      ||||||{ }           
 rAspThrValGlySerAlaGlnProGlnThrValThrSerSerGln{A}++         
 AGATACAGTGGGCTCTGCTCAGCCCCAGACTGTGACCAGTTCCCAG{A}gt         

 et Intron 3 >>>>  {rg}GluThrLeuProGlyAlaArgAsnLysValLysGlyAs
  552 bp           {  }|||   |||   |||      ||||||||||||   ||
                 -+{sn}GluAlaLeuPheGlyThrLysAsnLysValLysSerAs
                 gg{AT}GAGGCCTTGTTTGGTACCAAGAATAAGGTCAAGAGCAA

 nSerAsnAlaIleSerLysAlaGluAlaGlyAlaGlyIleMetGlySerValGlnValGl
 |   |||      ||||||||||||||||||||||||   |||||||||         ||
 nThrAsnThrValSerLysAlaGluAlaGlyAlaGlyThrMetGlySerAlaLysSerGl
 TACCAATACTGTGTCTAAGGCAGAGGCTGGGGCAGGTACAATGGGCTCTGCCAAGTCCCA

 nValValAlaSerPheGlnGlyGluValLeuProGlyAlaLysAsnLysValArgGlyAs
 |   |||         |||   |||   |||   ||||||   |||||||||   |||||
 nThrValThrThrSerGlnSerGluThrLeuLeuGlyAlaArgAsnLysValLysGlyAs
 GACTGTGACCACTTCCCAAAGTGAAACCTTGCTTGGTGCCCGGAATAAGGTCAAGGGTAA

 nSerAsnAlaValProLysAlaGluAlaGlyAlaAspThrValGlySerAlaGlnProGl
 |||||||   |||   ||||||||||||||||||   |||      |||   |||   ||
 nSerAsnIleValSerLysAlaGluAlaGlyAlaGlyThrLeuSerSerIleGlnSerGl
 TTCTAATATTGTGTCTAAAGCAGAGGCTGGGGCAGGTACATTGAGCTCTATCCAGAGCCA

 nAlaValAlaAsnSerGlnSerGluThrLeuLeuGlyAlaArgAsnLysValLysGlyAs
 |||||||               |||   ||||||||||||||||||||||||   |||||
 nAlaValAspSerPheLeuGlyGluAsnLeuLeuGlyAlaArgAsnLysValArgGlyAs
 GGCTGTGGATAGTTTCCTGGGGGAGAACTTGCTTGGTGCCAGGAATAAGGTCAGAGGCAA

 nThrIleAlaValProLysAlaGlyThrGlyAlaGlyThrArgHisSerAlaGlnProGl
 |      |||   ||||||   |||   ||||||      |||   |||   ||||||||
 nAlaAsnAlaAlaProLysThrGlyAlaGlyAlaAsnArgArgGlySerThrGlnProGl
 TGCTAATGCTGCTCCTAAAACAGGGGCTGGGGCAAATAGAAGGGGCTCTACCCAGCCCCA

 nIleValAlaGlySerGlnGlyGluThrLeuProGlyAlaArgAspLysSerMetSerTh
 |   |||      ||||||||||||   ||||||   ||||||||||||   |||     
 nThrValGlySerSerGlnGlyGluValLeuProArgAlaArgAspLysAlaMetProSe
 AACTGTGGGAAGTTCCCAGGGTGAAGTCTTGCCTAGGGCAAGGGACAAAGCTATGCCTAG

 rSerGluAlaGluAlaThrAlaGluAspGluAlaTyrAlaLysProGluAlaGluAlaMe
  ||||||   |||||||||   |||   |||   |||   |||   ||||||   |||  
 rSerGluValGluAlaThrThrGluGlyGluValTyrProLysArgGluAlaLeuAlaVa
 TTCTGAGGTGGAAGCCACAACAGAAGGTGAGGTCTATCCAAAGCGAGAAGCTCTGGCAGT

 tProThrSerGluSerGluGlyGlySerGlyThrGlnAlaCysArgLysThrGlnProAs
     ||||||||||||||||||      |||      |||   ||||||||||||     
 lSerThrSerGluSerGluGlyValThrGlyAlaGluAlaSerArgLysThrGlnThrAs
 GTCCACTTCTGAGAGTGAGGGTGTGACAGGTGCTGAGGCCTCTAGAAAGACTCAGACTGA

 nIleHisAspTyrTyrTrpAsnGlyIleGlyValGluAspTrpIleAlaAlaGluArgTr
  |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 pIleHisAspTyrTyrTrpAsnGlyIleGlyValGluAspTrpIleAlaAlaGluArgTr
 TATCCATGACTACTACTGGAATGGAATTGGTGTTGAAGATTGGATTGCTGCTGAGCGGTG

 pIleLysPheArgPheGlnThrMetAspGlyAspTrpGluAsnSerValSerTrpAlaAs
 |||||||||||||||||||   |||||||||||||||||||||      |||||||||||
 pIleLysPheArgPheGlnAlaMetAspGlyAspTrpGluAsnAsnMetSerTrpAlaAs
 GATCAAATTTAGGTTTCAGGCCATGGATGGAGATTGGGAGAATAATATGTCTTGGGCTGA

 pAspGluAsnGluAlaSerIleGlySerTrpSerGlyAlaSerAspLysAlaGlyIleIl
 |||||||||||||         |||   |||||||||   ||||||||||||||||||||
 pAspGluAsnGluIleAsnValGlyAlaTrpSerGlySerSerAspLysAlaGlyIleIl
 TGATGAGAATGAAATTAATGTTGGGGCCTGGAGTGGGTCTTCTGACAAGGCTGGTATTAT

 eArgSerTrpAlaValAlaCysAspGluThrSerValLysSerTrpAlaGlyAlaArgAl
 ||||||||||      |||            |||   |||||||||   |||        
 eArgSerTrpThrMetAlaPheSerGlyAlaSerIleLysSerTrpThrGly--------
 TAGGTCCTGGACTATGGCTTTTTCTGGGGCCAGCATTAAGTCCTGGACTGGG--------

 aGluAsnValValGlyIleGlyThrTrpAlaArgAlaGlyGluGlnAlaSerGlyGlyLe
     |||   |||      |||   ||||||      |||   ||||||   ||||||||
 ----AsnGluValAlaLeuGlySerTrpAlaGlyProGlyAspGlnAlaCysGlyGlyLe
 ----AATGAGGTTGCTCTTGGGTCCTGGGCTGGACCTGGGGACCAGGCCTGTGGAGGACT

 uTrpAlaGlyGlyGlnThrSerGluGlyThrTrpAlaGlyAspLysAlaSerGlyGlyAl
 ||||||||||||||||   |||||||||   |||||||||||||||||||||||||||  
 uTrpAlaGlyGlyGlnAlaSerGluGlySerTrpAlaGlyAspLysAlaSerGlyGlySe
 CTGGGCTGGGGGTCAGGCTAGTGAGGGGTCCTGGGCTGGGGACAAGGCCAGTGGGGGTTC

 a{Tr}  >>>> Target Intron 4 >>>>  {p}ThrGlyAlaGluAsnGlnAlaSe
  {||}            36 bp            {|}||||||   |||||||||   ||
 r{Tr}+-                         -+{p}ThrGlyIleGluAsnGlnAspSe
 T{TG}gg                         tg{G}ACTGGGATTGAGAACCAGGACAG

 rGlyGlySerTrpAlaLeuAlaGlyAsnGlnAlaIleGlyGluLeuTrpAlaAlaGlyGl
 ||||||||||||||||      ||||||||||||||||||      ||||||   |||||
 rGlyGlySerTrpAla---SerGlyAsnGlnAlaIleGlyGlyProTrpAlaGlyGlyGl
 TGGTGGGTCTTGGGCT---TCTGGAAACCAGGCCATTGGAGGGCCCTGGGCTGGGGGTCA

 nAlaSerAspGlySerTrpProGlyGlyGlnAlaSerGlyValSerTrpValGlyGluGl
 |||||||   |||||||||||||||||||||   ||||||   ||||||   ||||||||
 nAlaSerGluGlySerTrpProGlyGlyGlnThrSerGlyIleSerTrpAlaGlyGluGl
 GGCCAGTGAAGGGTCTTGGCCTGGGGGCCAGACCAGTGGGATCTCCTGGGCTGGGGAAGA

 uAlaIleGlyGlySerTrpThrGlyAlaGluAsnGlnAlaSerGluGlySerTrpAlaGl
 |||||||||||||||||||||||||      ||||||   |||   ||||||||||||||
 uAlaIleGlyGlySerTrpThrGly------AsnGlnAspSerGlyGlySerTrpAlaGl
 GGCTATTGGAGGGTCTTGGACTGGG------AACCAGGACAGTGGAGGATCTTGGGCTGG

 yAlaGlyAlaGlyAsnMetSerSerValSerTyrTrpAlaGlyValValAspGlnAlaGl
 |   |||||||||||||||            ||||||   |||   ||||||||||||  
 yThrGlyAlaGlyAsnMetGlyThrIleGlyTyrTrpThrGlyGlyValAspGlnAlaSe
 GACTGGGGCTGGGAATATGGGTACTATTGGGTACTGGACTGGGGGTGTGGATCAGGCTAG

 yGlyGlySerTrpAlaGlyThrSerAspGlnSerGlyGlyGlySerLysProArgPheGl
  |||||||||||||||||||||      ||||||||||||||||||||||||   |||  
 rGlyGlySerTrpAlaGlyThrAspHisGlnSerGlyGlyGlySerLysProValPheMe
 TGGTGGGTCCTGGGCTGGGACTGATCATCAATCTGGGGGTGGGTCCAAGCCTGTATTTAT

 uAspGlnAlaSerGlyGluGlySerTrpAlaGlyAlaGlyGlyGlnAlaSerGlyGlySe
  |||||||||            ||||||||||||   |||||||||||||||   |||||
 tAspGlnAlaAsnGluLysGluSerTrpAlaGlyThrGlyGlyGlnAlaSerGluGlySe
 GGATCAGGCTAATGAAAAAGAATCTTGGGCTGGGACTGGTGGCCAGGCCAGTGAAGGGTC

 rMetLeuGlyProGluAspGlnSerSerGlyArgSerTrpAlaAspThrAlaAspGlnAl
 |   ||||||||||||   ||||||||||||||||||||||||   |||   |||     
 rArgLeuGlyProGluAsnGlnSerSerGlyArgSerTrpAlaGlyThrValAspArgVa
 CAGGTTGGGTCCTGAGAACCAGTCTAGTGGAAGGTCTTGGGCTGGGACTGTGGACCGAGT

 aSerGlyGlySerArgLeuGlyHisValAspGlnSerSerGlyGlyAlaTrpAlaGlyTh
  |||||||||||||||||||||   ||||||||||||||||||      ||||||   ||
 lSerGlyGlySerArgLeuGlyLeuValAspGlnSerSerGlySerProTrpAlaAspTh
 CAGTGGAGGGTCTAGGCTGGGGCTTGTAGACCAGTCCAGTGGAAGTCCCTGGGCTGACAC

 rLeuAspGlnSerGlyGlyGlySerLysProArgPheGluAsnGlnThrThrGluGluGl
 |   ||||||   ||||||||||||||||||            |||         |||  
 rGluAspGlnAlaGlyGlyGlySerLysProGlySerMetAspGlnProGlyGlyGluPr
 TGAGGACCAGGCTGGTGGAGGGTCTAAGCCAGGGTCCATGGACCAACCAGGTGGAGAGCC

 ySerTrpAlaGlyAlaGlyGlyGlnAlaGlyGlyGlySerLysValGlyProGluAspGl
                             ||||||   ||||||         |||   ||
 oTrpAlaGlyThrGlyAsnGlnSerSerGlyGly---SerLysProArgPheGluAsnGl
 CTGGGCTGGGACAGGTAACCAGTCTAGTGGTGGA---TCTAAACCTAGATTTGAGAATCA

 nSerSerGlyArgSerTrpAlaAsnSerGlyAspGlnIleSerGlyGlyPheLeuValGl
 |   |||                                                     
 nAlaSer-----------------------------------------   //